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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 6059 products of "Apoptosis"

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  • CHS-828 nicotinate

    CAS:
    CHS-828, or GMX-1778, is a potent NAMPT inhibitor with anticancer properties, active against tumors and enhanced by certain drugs.
    Formula:C25H27ClN6O3
    Color and Shape:Solid
    Molecular weight:494.97
  • CAM 833

    CAS:
    <p>CAM 833 inhibits BRCA2-RAD51 interaction; Kd for ChimRAD51 is 366 nM, disrupts RAD51 oligocoagulation, and induces apoptosis in G2/M cells.</p>
    Formula:C26H26ClFN4O5
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:528.96
  • Topoisomerase IIα-IN-3

    CAS:
    Topoisomerase IIα-IN-3 is a DNA-inserting topoisomerase-Iiα inhibitor that blocks the cell cycle in G0/G1 phase and induces apoptosis.
    Formula:C29H20N6O2S
    Color and Shape:Solid
    Molecular weight:516.57
  • HL271

    CAS:
    HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment.
    Formula:C13H17ClF3N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:351.76
  • KY1022

    CAS:
    KY1022 is a ras destabilizer. KY1022 targets the Wnt/ß-catenin pathway and inhibits development of metastatic colorectal cancer.
    Formula:C17H19N3OS
    Color and Shape:Solid
    Molecular weight:313.42
  • ML132

    CAS:
    ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM).
    Formula:C22H28ClN5O5
    Color and Shape:Solid
    Molecular weight:477.94
  • NSC405640

    CAS:
    NSC405640 selectively inhibits MDM2-p53 interaction, restoring mutated p53 structure; halts growth of cells with normal p53. [1]
    Formula:C12H10Cl2Sn
    Color and Shape:Solid
    Molecular weight:343.82
  • MBM-17

    CAS:
    MBM-17 is a potent inhibitor of NIMA-related kinase 2 (Nek2,IC50 of 3 nM).
    Formula:C28H28N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:480.56
  • TH1834 dihydrochloride

    CAS:
    TH1834 dihydrochloride is a specific Tip60 histone acetyltransferase inhibitor.
    Formula:C33H42Cl2N6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:641.63
  • MpsBAY2a

    CAS:
    carcinoma cell proliferation.
    Formula:C29H28N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:476.57
  • CTX1

    CAS:
    CTX1 is a small molecule activator of p53.
    Formula:C14H10N4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:234.26
  • pan-HER-IN-1

    CAS:
    <p>Compound C5: Irreversible, oral pan-HER inhibitor with low IC50s for EGFR/HERs; induces apoptosis and has antitumor effects.</p>
    Formula:C19H14BrN5O
    Color and Shape:Solid
    Molecular weight:408.25
  • SLMP53-2

    CAS:
    SLMP53-2 is a mutant p53 reactivator that restores the wild-type-like conformation and DNA-binding ability of mutp53-Y220C through enhanced interaction with
    Formula:C26H22N2O2
    Color and Shape:Solid
    Molecular weight:394.47
  • Epirubicin

    CAS:
    Epirubicin, a doxorubicin derivative, is an antineoplastic, inhibits topoisomerase, DNA/RNA synthesis, and Foxp3, reducing T cell activity.
    Formula:C27H29NO11
    Color and Shape:Solid
    Molecular weight:543.52
  • Antitumor agent-81

    CAS:
    Antitumor agent-81, a P62-RNF168 agonist, reduces H2A ubiquitination, hinders DNA repair, and inhibits tumor growth.
    Formula:C19H19N7O3
    Color and Shape:Solid
    Molecular weight:393.4
  • MYRA-A

    CAS:
    MYRA-A is an inducer of apoptosis in a Myc-dependent manner that acts by inhibiting Myc-driven transformation and disrupting MYC-Max interaction.
    Formula:C19H20N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:340.37
  • W146 TFA

    CAS:
    W146 TFA is a selective sphingosine-1-phosphate receptor 1 ( S1PR1 ) antagonist with an EC 50 value of 398 nM.
    Formula:C18H28F3N2O6P
    Color and Shape:Solid
    Molecular weight:456.399
  • 2-chloro Palmitic Acid

    CAS:
    2-chloro Palmitic acid triggers NETosis, elevates COX-2, adhesion molecules in HCAECs, and induces apoptosis and caspase-3 in THP-1 cells/monocytes.
    Formula:C16H31ClO2
    Color and Shape:Solid
    Molecular weight:290.87
  • Psammaplysene A

    CAS:
    Psammaplysene A is a FOXO1a nuclear export inhibitor.
    Formula:C27H35Br4N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:769.2
  • CDK8/19-IN-1

    CAS:
    CDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, and 270 nM for CDK8, CDK19, and CDK9).
    Formula:C19H18N4O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:430.5