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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 6059 products of "Apoptosis"

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  • PBOX-15

    CAS:
    PBOX-15 induces apoptosis, regulates death receptors, enhances TRAIL effects, and inhibits T cell migration in myeloma cells.
    Formula:C28H19NO3
    Color and Shape:Solid
    Molecular weight:417.46
  • Paclitaxel Ceribate

    CAS:
    Paclitaxel Ceribate is a mitotic inhibitor used in cancer chemotherapy.
    Formula:C51H57NO18
    Color and Shape:Solid
    Molecular weight:971.99
  • C1A

    CAS:
    C1A is an inhibitor of HDAC6 which modulates downstream autophagy substrates and leads to growth inhibition of a diverse set of cancer cell lines.
    Formula:C22H25Cl2N3O4S
    Color and Shape:Solid
    Molecular weight:498.42
  • S65487

    CAS:
    S65487 (VOB560) inhibits Bcl-2, including G101V and D103Y variants, while sparing MCL-1, BFL-1, and BCL-XL, supporting its anticancer potential.
    Formula:C41H41ClN6O4
    Purity:99.034%
    Color and Shape:Solid
    Molecular weight:717.26
  • APX2009

    CAS:
    APX2009, a 2nd-gen APE1/Ref-1 inhibitor, curbs NFkB activity, survivin, and prostate cancer cell growth; induces cell cycle arrest.
    Formula:C21H25NO4
    Color and Shape:Solid
    Molecular weight:355.43
  • Ceranib-2

    CAS:
    <p>Ceranib-2, a ceramidase inhibitor (IC50: 28 μM, SKOV3), reduces sphingosine/S1P and promotes apoptosis, showing anticancer properties.</p>
    Formula:C25H19NO3
    Purity:98.49%
    Color and Shape:Solid
    Molecular weight:381.42
  • F5446

    CAS:
    F5446 is a selective small molecule SUV39H1 methyltransferase inhibitor, promotes apoptosis in colorectal cancer cells by inhibiting the deposition of H3K9me3.
    Formula:C26H17ClN2O8S
    Purity:98.56%
    Color and Shape:Solid
    Molecular weight:552.94
  • BEPP monohydrochloride

    CAS:
    BEPP monohydrochloride is a double-strand RNA-dependent protein kinase (PKR) activator.
    Formula:C23H24ClN3O2
    Color and Shape:Solid
    Molecular weight:409.91
  • TNF-α-IN-10

    CAS:
    TNF-α-IN-10 (compound 8a) acts as an inhibitor of IL-6 and TNF-α, demonstrating anti-inflammatory activity [1].
    Formula:C17H14O4
    Color and Shape:Solid
    Molecular weight:282.29
  • Methylisothiazolinone

    CAS:
    Methylisothiazolinone (MI) is a powerful synthetic biocide and preservative within the group of isothiazolinones.
    Formula:C4H5NOS
    Purity:99.78%
    Color and Shape:Colorless Prisms Liquid
    Molecular weight:115.15
  • CMLD010509

    CAS:
    CMLD010509 (SDS-1-021) inhibits oncogenic proteins MDM2, CCND1, MYC, MAF, MCL-1 in multiple myeloma.
    Formula:C27H26BrNO7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:556.4
  • Topoisomerase I inhibitor 5

    CAS:
    <p>Topoisomerase I inhibitor 5 halts DNA replication, induces MCF-7 cell apoptosis, and overcomes drug resistance. IC50 value is noted.</p>
    Formula:C24H24N2O2
    Color and Shape:Solid
    Molecular weight:372.46
  • HDAC1/2 and CDK2-IN-1

    CAS:
    Compound 14d inhibits HDAC1 (IC50=70.7μM), HDAC2 (23.1μM), CDK2 (0.80μM), blocks cell cycle, induces apoptosis, and shows in vivo anti-tumor effects.
    Formula:C26H22ClN7O
    Color and Shape:Solid
    Molecular weight:483.95
  • CMLD012073

    CAS:
    CMLD012073: Potent eIF4A inhibitor, halts eukaryotic translation; IC50 10 nM in NIH/3T3 cells.
    Formula:C30H30N2O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:530.57
  • RET-IN-22

    CAS:
    RET-IN-22 (compound 17b) is a potent, selective, and orally active inhibitor of RET, exhibiting IC50 values of 20.9 nM for wild-type RET and 18.3 nM for RET-
    Formula:C29H31F3N6O4
    Color and Shape:Solid
    Molecular weight:584.59
  • Nampt-IN-8

    CAS:
    Nampt-IN-8 is a NAMPT inhibitor (IC50: 0.183 μM) and a good substrate for NQO1. Nampt-IN-8 induces reactive oxygen species (ROS) production and apoptosis.
    Formula:C36H35N3O4
    Color and Shape:Solid
    Molecular weight:573.68
  • NVX-207

    CAS:
    NVX-207 is a derivative of betulinic acid. It has anti-cancer activity.
    Formula:C36H59NO6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:601.86
  • IMM-02

    CAS:
    IMM-02 is a DID-DAD binding inhibitor.
    Formula:C13H17F2N3OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:301.36
  • ARN5187

    CAS:
    ARN5187, a lysosomal REV-ERB β ligand, inhibits transcription and autophagy, shows efficacy, cytotoxicity, and induces apoptosis.
    Formula:C24H32FN3O
    Color and Shape:Solid
    Molecular weight:397.53
  • Clidanac

    CAS:
    Clidanac is a potent anti-inflammatory drug and is found to uncouple the oxidative phosphorylation.
    Formula:C16H19ClO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:278.77