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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 6063 products of "Apoptosis"

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  • SHP2-IN-8

    CAS:
    SHP2-IN-8: reversible, selective SHP2 inhibitor; IC50=23 nM; induces AKT dephosphorylation and Hela cell apoptosis.
    Formula:C17H21Cl2N5S
    Color and Shape:Solid
    Molecular weight:398.35
  • Flupenthixol

    CAS:
    Flupentixol is a typical antipsychotic drug of the thioxanthene class. Flupentixol is also used in low doses as an antidepressant.
    Formula:C23H25F3N2OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:434.52
  • KRAS G12D inhibitor 14

    CAS:
    <p>KRAS G12D inhibitor 14 is a potent inhibitor of KRAS G12D that binds KRAS G12D protein (Kd: 33 nM).</p>
    Formula:C20H19F3N4OS
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:420.45
  • HDAC-IN-39

    CAS:
    <p>HDAC-IN-39 inhibits HDAC1-3 (IC50: 1.07-2.27 μM), arrests G2/M phase, hinders microtubule polymerization, and is effective against drug-resistant cancers.</p>
    Formula:C27H26N4O4S
    Color and Shape:Solid
    Molecular weight:502.58
  • 3-ATA

    CAS:
    <p>3-ATA is a selective cyclin-dependent kinase 4 (Cdk4) inhibitor, attenuating kainic acid-induced apoptosis in neurons.</p>
    Formula:C13H10N2S
    Color and Shape:Solid
    Molecular weight:226.3
  • S130

    CAS:
    S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 μM).It suppresses autophagy flux.
    Formula:C24H25N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:387.47
  • Topoisomerase II inhibitor 9

    CAS:
    <p>Topoisomerase II inhibitor 9: Topo II blocker (IC50: 0.97 μM), DNA intercalator (IC50: 43.51 μM), arrests G2/M in Hep G-2 cells and triggers apoptosis.</p>
    Formula:C22H17N7O3S2
    Color and Shape:Solid
    Molecular weight:491.55
  • OT-82

    CAS:
    OT-82 is a NAMPT inhibitor with anticancer activity and cytotoxicity and is used in the study of leukemias.
    Formula:C26H21FN4O
    Purity:98.91% - 99.315%
    Color and Shape:Solid
    Molecular weight:424.47
  • Nimustine

    CAS:
    Nimustine: treats brain tumors, used with other drugs or radiotherapy for neoplasms.
    Formula:C9H13ClN6O2
    Color and Shape:Solid
    Molecular weight:272.69
  • HS56

    CAS:
    HS56: ATP-competitive Pim/DAPK3 inhibitor, Ki: DAPK3 (0.26μM), Pim-3 (0.208μM), Pim-1 (2.94μM), Pim-2 (>100μM), reduces hypertension in mice.
    Formula:C13H8ClN5OS
    Color and Shape:Solid
    Molecular weight:317.75
  • WK-298

    CAS:
    WK-298 is an effective MDM2/MDMX-p53 interaction inhibitor.
    Formula:C35H38Cl2N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:629.62
  • NSC-741909

    CAS:
    NSC-741909 is an anticancer agent that acts by suppressing the growth of several cell lines.
    Formula:C16H14ClNO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:271.74
  • ATB-337

    CAS:
    S-Diclofenac, an NSAID with H2S-releasing moiety, protects gastric mucosa while inhibiting prostaglandins.
    Formula:C23H15Cl2NO2S3
    Color and Shape:Solid
    Molecular weight:504.47
  • KF24345

    CAS:
    KF24345 is an inhibitor of adenosine uptake.
    Formula:C31H38N6O5
    Color and Shape:Solid
    Molecular weight:574.67
  • Merck-22-6

    CAS:
    Merck-22-6 is an allosteric dual inhibitor of Akt1, Akt2.
    Formula:C40H43N7O2
    Color and Shape:Solid
    Molecular weight:653.82
  • NU-8165

    CAS:
    NU-8165 is an MDM2-p53 protein-protein interaction inhibitor.
    Formula:C24H22ClNO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:407.89
  • Dabuzalgron HCl

    CAS:
    Dabuzalgron, an adrenoceptor agonist, is used potentially for the treatment of urinary incontinence.
    Formula:C12H17Cl2N3O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:354.25
  • SMI-6860766

    CAS:
    SMI-6860766 is a CD40-Traf6 interactions blocker that acts by ameliorating the complications of diet-induced obesity in mice.
    Formula:C15H11BrClNO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:336.61
  • BPTQ

    CAS:
    BPTQ: DNA intercalator, halts cancer cell growth by blocking S/G2/M phases.
    Formula:C17H16N4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:308.4
  • Anticancer agent 57

    CAS:
    Anticancer agent 57 blocks TNBC cell growth with IC50: 6.43-8 μM, induces apoptosis, and shrinks tumors in mice.
    Formula:C20H21Cl2NO2
    Color and Shape:Solid
    Molecular weight:378.29