Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(5 products)
- Caspase(151 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(105 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(58 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6043 products of "Apoptosis"
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Prexasertib mesylate
CAS:Prexasertib (LY2606368), a Chk1/2 inhibitor, enhances therapy in acute lymphoblastic leukemia, causing DNA damage and antitumor effects.Formula:C19H23N7O5SPurity:98%Color and Shape:SolidMolecular weight:461.49Verrucarin J
CAS:Verrucarin J, a Myrothecium fungus metabolite, triggers apoptosis in some cancer cells and fights Candida, Mucor, and JUNV (IC50: 1.2 ng/mL).Formula:C27H32O8Color and Shape:SolidMolecular weight:484.54PAK4-IN-2
CAS:PAK4-IN-2 inhibits PAK4 with IC50 2.7 nM, arrests MV4-11 cells at G0/G1, and induces apoptosis, promising for cancer research.Formula:C18H21ClN6Color and Shape:SolidMolecular weight:356.85PARP-1-IN-2
CAS:PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM).PARP-1-IN-2 showed significant antiproliferative activity against
Formula:C22H15Cl2N3O2Purity:98.82%Color and Shape:SolidMolecular weight:424.28Erasin
Erasin is a STAT3 inhibitor induces apoptosis in various cancer cell lines (e.g., MDA-MB-231, HCC-827) and against Erlotinib-resistant cancer cells.Formula:C20H19N3O3Color and Shape:SolidMolecular weight:349.38PD180970
CAS:PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit.Formula:C21H15Cl2FN4OPurity:98.67%Color and Shape:SolidMolecular weight:429.27NSC745887
CAS:NSC745887 (compound 25) is an anticancer agent that demonstrates dose-dependent inhibition of proliferation across 60 cancer cell lines [1].Formula:C16H8N2O2Color and Shape:SolidMolecular weight:260.25SMU127
CAS:SMU127 is an agonist of the toll-like receptor 1/2 (TLR1/2) heterodimer.Formula:C16H23N3O3SColor and Shape:SolidMolecular weight:337.44PBOX-15
CAS:PBOX-15 induces apoptosis, regulates death receptors, enhances TRAIL effects, and inhibits T cell migration in myeloma cells.Formula:C28H19NO3Color and Shape:SolidMolecular weight:417.46Paclitaxel Ceribate
CAS:Paclitaxel Ceribate is a mitotic inhibitor used in cancer chemotherapy.Formula:C51H57NO18Color and Shape:SolidMolecular weight:971.99C1A
CAS:C1A is an inhibitor of HDAC6 which modulates downstream autophagy substrates and leads to growth inhibition of a diverse set of cancer cell lines.Formula:C22H25Cl2N3O4SColor and Shape:SolidMolecular weight:498.42APX2009
CAS:APX2009, a 2nd-gen APE1/Ref-1 inhibitor, curbs NFkB activity, survivin, and prostate cancer cell growth; induces cell cycle arrest.Formula:C21H25NO4Color and Shape:SolidMolecular weight:355.43Ceranib-2
CAS:Ceranib-2, a ceramidase inhibitor (IC50: 28 μM, SKOV3), reduces sphingosine/S1P and promotes apoptosis, showing anticancer properties.
Formula:C25H19NO3Purity:98.49%Color and Shape:SolidMolecular weight:381.42MSN-50
CAS:MSN-50, an inhibitor of Bax and Bak oligomerization, inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection.Formula:C36H38BrN3O6Color and Shape:SolidMolecular weight:688.61F5446
CAS:F5446 is a selective small molecule SUV39H1 methyltransferase inhibitor, promotes apoptosis in colorectal cancer cells by inhibiting the deposition of H3K9me3.Formula:C26H17ClN2O8SPurity:98.56%Color and Shape:SolidMolecular weight:552.94BEPP monohydrochloride
CAS:BEPP monohydrochloride is a double-strand RNA-dependent protein kinase (PKR) activator.Formula:C23H24ClN3O2Color and Shape:SolidMolecular weight:409.91LY5
CAS:LY5 is an inhibitor of STAT3 that acts by inhibiting cell viability, cell migration, and angiogenesis in medulloblastoma cells.Formula:C15H11N3O4SPurity:98%Color and Shape:SolidMolecular weight:329.33IMM-02
CAS:IMM-02 is a DID-DAD binding inhibitor.Formula:C13H17F2N3OSPurity:98%Color and Shape:SolidMolecular weight:301.36Sparfosic acid trisodium
CAS:Sparfosic acid trisodium is a CAD (carbamoyl-phosphate synthetase 2) inhibitor and also an aspartate transcarbamoyl transferase inhibitor with antitumourFormula:C6H9NNaO8PPurity:98%Color and Shape:SolidMolecular weight:277.1IHMT-TRK-284
CAS:IHMT-TRK-284: Oral type II TRK inhibitor; targets TRKA, TRKB, TRKC (IC50s: 10.5, 0.7, 2.6 nM); selective and anti-tumor effective.Formula:C25H27N7OSColor and Shape:SolidMolecular weight:473.59
