Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(6 products)
- Caspase(151 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(106 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(59 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6043 products of "Apoptosis"
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Mcl-1 inhibitor 10
CAS:Mcl-1 inhibitor10 (compound 43) is a relatively potent MCL-1 inhibitor with an IC50 of 0.67 μM. It interacts with a specific binding site on the MCL-1 protein, disrupting its pro-survival signals and inducing apoptosis in cancer cells. This compound is useful for research on MCL-1-dependent cancers.Formula:C21H15F3O4Color and Shape:SolidMolecular weight:388.34PDK4-IN-1
CAS:PDK4-IN-1 is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4)(IC50 value of 84 nM).Formula:C22H19N3O2Purity:98%Color and Shape:SolidMolecular weight:357.41LLL3
CAS:LLL3 is a small molecule STAT3 inhibitor.Formula:C16H10O4Color and Shape:SolidMolecular weight:266.25W1131
CAS:W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.Formula:C23H19N5O4Color and Shape:SolidMolecular weight:429.43Erasin
Erasin is a STAT3 inhibitor induces apoptosis in various cancer cell lines (e.g., MDA-MB-231, HCC-827) and against Erlotinib-resistant cancer cells.Formula:C20H19N3O3Color and Shape:SolidMolecular weight:349.38N1,N11-Diethylnorspermine
CAS:DENSPM: potent anticancer, spurs polyamine breakdown, triggers cytochrome c release and caspase 3, kills GBM via SSAT & H2O2.Formula:C13H32N4Color and Shape:SolidMolecular weight:244.42Lemuteporfin
CAS:Lemuteporfin is a light-activated photosensitizing agent confers cytotoxic upon light activation.reduce sebaceous gland volume in animal studies.Formula:C44H48N4O10Purity:97.14% - 99.44%Color and Shape:SolidMolecular weight:792.87R-8507
CAS:R-8507: TNF-αRI antagonist, blocks ICAM-1, halts receptor complex internalization, EC50: 2.45 μM (TNF-α), 3.79 μM (IL-1β).Formula:C16H8ClF3N4Color and Shape:SolidMolecular weight:348.71PARP1-IN-31
CAS:PARP1-IN-31 (compound 11f) is a PARP1 inhibitor with an IC₅₀ of 97 nM. It induces apoptosis and inhibits proliferation in lung cancer cell lines (e.g., A549).Formula:C22H15ClFN3O2Purity:98.99%Color and Shape:SolidMolecular weight:407.83GRI977143
CAS:GRI977143: selective LPA2 agonist (EC50=3.3μM), blocks caspases 3/7/8/9, limits DNA fragmentation.Formula:C22H17NO4SPurity:99.08%Color and Shape:SolidMolecular weight:391.44NKP-1339
CAS:NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.Formula:C14H12Cl4N4NaRuPurity:98%Color and Shape:SolidMolecular weight:502.14Flonoltinib
CAS:Flonoltinib (JAK2/FLT3-IN-1) is an orally active and efficient JAK2/FLT3 inhibitor with anti-cancer properties.
Formula:C25H34FN7OPurity:99.52%Color and Shape:SolidMolecular weight:467.58BR102375
CAS:BR102375 is a non-TZD PPAR γ full agonist (EC50: 0.28 μM) for the treatment of type 2 diabetes.Formula:C31H34N6O4Purity:98%Color and Shape:SolidMolecular weight:554.64Antitumor agent-44
CAS:Antitumor agent-44 (Compound 5n) elicits potent antitumor effects by inducing disruption of mitochondrial homeostasis, cell cycle arrest, and apoptosis in humanFormula:C24H15N3O3Color and Shape:SolidMolecular weight:393.39Sparfosic acid trisodium
CAS:Sparfosic acid trisodium is a CAD (carbamoyl-phosphate synthetase 2) inhibitor and also an aspartate transcarbamoyl transferase inhibitor with antitumourFormula:C6H9NNaO8PPurity:98%Color and Shape:SolidMolecular weight:277.1ATAD2-IN-1
CAS:ATAD2-IN-1 (compound 19f) serves as a potent ATAD2 inhibitor (IC 50: 0.27 μM), capable of inducing apoptosis. Additionally, it suppresses c-Myc activation and impedes the migration of BT-549 cells [1].Formula:C22H26N6O5Color and Shape:SolidMolecular weight:454.48RET-IN-12
CAS:RET-IN-12 is a RET inhibitor capable of acting on RET(WT) (IC50: 0.3 nM) and RET(V804M) (IC50: 1 nM).Formula:C30H30F3N5O4Color and Shape:SolidMolecular weight:581.59PDE5/HDAC-IN-1
CAS:PDE5/HDAC-IN-1 is a potent inhibitor of phosphodiesterase 5 (PDE5) and HDAC, with IC50 values of 46.3 nM and 14.5 nM, respectively.Formula:C27H29BrN4O4Color and Shape:SolidMolecular weight:553.45Cinnabarinic acid
CAS:mGlu4 receptor agonistFormula:C14H8N2O6Purity:98%Color and Shape:SolidMolecular weight:300.22Tezacitabine
CAS:Tezacitabine, a nucleoside analogue, inhibits ribonucleotide reductase, disrupts DNA replication, and induces apoptosis in tumor cells.Formula:C10H12FN3O4Color and Shape:SolidMolecular weight:257.22
