Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(8 products)
- Caspase(145 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(140 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(92 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6109 products of "Apoptosis"
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cRIPGBM chloride
CAS:cRIPGBM chloride is a pro-apoptotic derivative found in GBM cancer stem cells with anti-tumor activity, inducing caspase-1-dependent apoptosis.Formula:C26H20ClFN2O2Purity:99.75%Color and Shape:SolidMolecular weight:446.9Sarmustine
CAS:<p>SarCNU is an alkylating anticancer drug targeting prostate cancer through p53 pathways and selects P140K MGMT-transduced CD34(+) cells.</p>Formula:C6H11ClN4O3Purity:98.29% - 99.71%Color and Shape:SolidMolecular weight:222.63NM-3
CAS:NM-3, an oral anti-angiogenic and anti-tumor agent, modulates radiation and blocks VEGF to curb endothelial growth and induce apoptosis.Formula:C13H12O6Purity:99.89%Color and Shape:SolidMolecular weight:264.23Ref: TM-T33701
1mg180.00€5mg457.00€10mg652.00€25mg1,026.00€50mg1,406.00€100mg1,890.00€500mg3,725.00€1mL*10mM (DMSO)416.00€AQ4
CAS:AQ4 is a topoisomerase II inhibitor and DNA-inserting agent that inhibits proliferation and induces apoptosis in two cell lines.Formula:C22H28N4O4Purity:96.28% - 97.15%Color and Shape:SolidMolecular weight:412.48GSK854
CAS:GSK854 is a selective TNNI3K inhibitor reducing heart damage and stress post-infarction in mice.Formula:C18H19ClN6O4S2Purity:98.91%Color and Shape:SolidMolecular weight:482.96Ref: TM-T24115
1mg97.00€5mg235.00€10mg378.00€25mg748.00€50mg1,121.00€100mg1,776.00€500mg3,562.00€1mL*10mM (DMSO)259.00€NecroX-7
CAS:NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor.Formula:C24H29N3O3SPurity:98.22%Color and Shape:SolidMolecular weight:439.57STAT3-IN-13
CAS:STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.Formula:C21H20N6O3SPurity:98.89%Color and Shape:SolidMolecular weight:436.49KR-33493
CAS:<p>KR-33493 is a FAS-associated factor 1 (FAF1) inhibitor and can be used in studies about Parkinson's disease.</p>Formula:C20H18BrN3O3SPurity:99.96%Color and Shape:SolidMolecular weight:460.34HS-276
CAS:HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; potential for RA research.Formula:C24H29N5O2Purity:97.67% - 98.81%Color and Shape:SolidMolecular weight:419.52Ref: TM-T62209
1mg66.00€5mg144.00€10mg219.00€25mg430.00€50mg690.00€100mg1,064.00€200mg1,434.00€1mL*10mM (DMSO)170.00€Deferitazole
CAS:Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.Formula:C18H25NO7SPurity:99.48%Color and Shape:SolidMolecular weight:399.46MJN68390
CAS:MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.Formula:C24H28ClN3O3Purity:98.86%Color and Shape:SolidMolecular weight:441.95FA16
FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16Formula:C22H27F3N4O2SPurity:99.44%Color and Shape:SolidMolecular weight:468.54VAS 3947
CAS:VAS 3947: NOX inhibitor, induces platelet apoptosis via UPR, not linked to NOX inhibition.Formula:C14H10N6OSPurity:99.25%Color and Shape:SolidMolecular weight:310.33Ref: TM-T29097
1mg48.00€5mg97.00€10mg170.00€25mg295.00€50mg424.00€100mg562.00€200mg743.00€1mL*10mM (DMSO)105.00€EGFR-IN-11
CAS:EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.Formula:C29H35N9O2SPurity:99.93%Color and Shape:SolidMolecular weight:573.71CMLD-2
CAS:CMLD-2 is a HuR-ARE inhibitor (Ki: 350 nM) that promotes apoptosis, has antitumor properties, and reduces thyroid cancer cell viability.Formula:C31H31NO6Purity:99.99%Color and Shape:SolidMolecular weight:513.58Ref: TM-T36493
1mg97.00€5mg235.00€10mg393.00€25mg642.00€50mg895.00€100mg1,206.00€500mg2,403.00€1mL*10mM (DMSO)259.00€CCT018159
CAS:<p>CCT018159: ATP-competitive HSP90 inhibitor, IC50 3.2 μM (human), 6.6 μM (yeast), blocks invasion, angiogenesis, induces G1 arrest and apoptosis.</p>Formula:C20H20N2O4Purity:98.78% - 99.79%Color and Shape:SolidMolecular weight:352.38Mitazalimab
CAS:Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.Purity:95.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 95.1% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:LiquidNSC49652
CAS:NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.Formula:C14H11NO2Purity:98.98%Color and Shape:SolidMolecular weight:225.24Ref: TM-T28206
1mg34.00€5mg74.00€10mg113.00€25mg222.00€50mg353.00€100mg530.00€500mg1,153.00€1mL*10mM (DMSO)82.00€Stemazole
CAS:Stemazole activates human stem cell growth, boosts survival, reduces cell death, and aids myelin repair, with therapeutic potential in demyelinating diseases.Formula:C9H9N5OS2Purity:98.59%Color and Shape:SolidMolecular weight:267.33Ref: TM-T28866
1mg52.00€5mg101.00€10mg164.00€25mg334.00€50mg532.00€100mg858.00€200mg1,149.00€1mL*10mM (DMSO)95.00€RO-5963
CAS:RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively).Formula:C24H21ClF2N4O5Purity:99.28%Color and Shape:SolidMolecular weight:518.9Ref: TM-T16771
1mg70.00€5mg197.00€10mg284.00€25mg434.00€50mg562.00€100mg780.00€200mg1,035.00€1mL*10mM (DMSO)224.00€
