Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(6 products)
- Caspase(151 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(106 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(59 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6043 products of "Apoptosis"
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Bcl-2-IN-13
CAS:Bcl-2-IN-13 is a potent inhibitor of Bcl-2, exhibiting an IC50 of 17 nM, and holds potential for use in cancer research [1].Formula:C42H44ClN7O6S3Color and Shape:SolidMolecular weight:874.49MI-888 free base
CAS:MI-888 is the most potent MDM2 inhibitor (Ki = 0.44 nM), with high oral efficacy in human cancer models and optimal pharmacokinetics.Formula:C28H32Cl2FN3O3Color and Shape:SolidMolecular weight:548.48Eeyarestatin I
CAS:Eeyarestatin I blocks ER protein degradation, hinders p97/atx3 processes, and induces anticancer proteins.Formula:C27H25Cl2N7O7Purity:98% - 98.99%Color and Shape:SolidMolecular weight:630.44MY-673
CAS:MY-673, a colchicine binding site inhibitor (CBSI), impedes tubulin polymerization and disrupts the ERK signaling pathway, consequently modulating SMAD4 proteinFormula:C18H14N2O4Color and Shape:SolidMolecular weight:322.31SWS1
CAS:SWS1, a d-(+)-biotin-conjugated PD-L1 inhibitor (IC50: 1.8 nM), displays anticancer activity by augmenting tumor-infiltrating lymphocytes and demonstrating antiFormula:C47H53ClN6O5SPurity:98%Color and Shape:SolidMolecular weight:849.48CA-170
CAS:PD-1-IN-1 is a programmed cell dealth-1inhibitor. PD-1-IN-1 can be used as an immune modulator.Formula:C12H20N6O7Purity:98%Color and Shape:SolidMolecular weight:360.32SW IV-52
CAS:SW IV-52 is an XIAP-inhibitor that acts as a second mitochondria-derived activator of caspases (SMAC) mimetic.Formula:C25H39ClN4O3Purity:98%Color and Shape:SolidMolecular weight:479.05Anticancer agent 118
CAS:Anticancer Agent 118, an N‑acylated ciprofloxacin derivative, exhibits antibacterial efficacy against Gram-positive strains and antiproliferative effects onFormula:C19H19ClFN3O4Color and Shape:SolidMolecular weight:407.82Thaspine acetate
CAS:Thaspine: inhibits topoisomerase IB, reduces VEGF, stops endothelial cell growth via PI3K/MAPK pathways.Formula:C22H23NO8Color and Shape:SolidMolecular weight:429.425Siremadlin (R Enantiomer)
CAS:Siremadlin R Enantiomer is the R enantiomer of Siremadlin. Siremadlin is a potent and highly specific inhibitor of MDM-2/p53.Formula:C26H24Cl2N6O4Purity:98%Color and Shape:SolidMolecular weight:555.4115-Deoxy-Δ12,14-prostaglandin A1
CAS:15-Deoxy-Δ12,14-Prostaglandin A1, a deoxyanalog of prostaglandins, inhibits NF-κB signaling and induces apoptosis. It also prevents TNF-α-induced upregulation of inflammatory endothelial cell adhesion molecules (CAM) and reduces monocyte arrest [1].Formula:C20H30O3Color and Shape:SolidMolecular weight:318.457(Rac)-Lisaftoclax
CAS:(Rac)-Lisaftoclax ((Rac)-APG-2575), a Bcl-2 inhibitor, is utilized in hematologic malignancy research (CN112898295A) [1].Formula:C45H48ClN7O8SColor and Shape:SolidMolecular weight:882.42Ezatiostat hydrochloride
CAS:Ezatiostat HCl (TLK199) inhibits glutathione S-transferase, GSTP1-1 specifically, and may treat cytopenias.Formula:C27H36ClN3O6SPurity:98%Color and Shape:SolidMolecular weight:566.11Ref: TM-T22776
2mg58.00€5mg82.00€10mg120.00€25mg200.00€50mg306.00€100mg517.00€200mg777.00€500mg1,165.00€1mL*10mM (DMSO)118.00€IM156
CAS:IM156, a Metformin derivative, activates AMPK, enhances cognition in aging animals, and inhibits OXPHOS in solid tumor research.Formula:C13H16F3N5OPurity:99.67%Color and Shape:SolidMolecular weight:315.29BCL6-IN-4
CAS:BCL6-IN-4, a potent inhibitor of B-cell lymphoma 6 (BCL6), exhibits anti-tumor activities with an inhibitory concentration 50 (IC50) value of 97 nM[1].Formula:C25H35ClN6O3Color and Shape:SolidMolecular weight:503.04EP1013
CAS:EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.Formula:C18H23FN2O6Purity:98%Color and Shape:SolidMolecular weight:382.38PLK1/BRD4-IN-1
CAS:PLK1/BRD4-IN-1 (9b) is an orally active dual inhibitor of PLK1 (IC50: 22 nM) and BRD4 (IC50: 109 nM).Formula:C31H43N9O2Color and Shape:SolidMolecular weight:573.73BAI1 hydrochloride
CAS:BAI1 hydrochloride is a selective inhibitor of the apoptosis factor BAX, functioning through an allosteric mechanism. By binding to BAX, it allosterically inhibits its activation, showcasing potential applications in the research of diseases mediated by BAX-dependent cell death [1].Formula:C19H23Br2Cl2N3OColor and Shape:SolidMolecular weight:540.12GSK-2245035 maleate
CAS:GSK-2245035 maleate is a selective Toll-like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties.Formula:C24H38N6O6Color and Shape:SolidMolecular weight:506.6Ac-YVAD-pNA
CAS:Ac-YVAD-pNA, a specific substrate for Caspase-1, serves to detect Caspase-1 activity, a crucial mediator of inflammatory processes [1] [2].Formula:C29H36N6O10Color and Shape:SolidMolecular weight:628.639
