Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(5 products)
- Caspase(151 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(105 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(58 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6043 products of "Apoptosis"
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N-Oleoyl serinol
CAS:N-Oleoyl serinol, a ceramide analog, plays a crucial role in stem cell therapy by inhibiting the development of teratomas in stem cells. It triggers apoptosis in remaining pluripotent embryoid body-derived cells (EBCs), thwarts teratoma formation, and promotes the enrichment of EBC cells that proceed to neural differentiation post-transplantation [1].Formula:C21H41NO3Color and Shape:SolidMolecular weight:355.563HS148
CAS:HS148 selectively inhibits DAPK3 (Ki 119 nM), reducing gastric cancer progression via ULK1-dependent autophagy and tumor suppression pathways.Formula:C15H14FN5O2SPurity:98.024%Color and Shape:SolidMolecular weight:347.37ICL-CCIC-0019
CAS:ICL-CCIC-0019 inhibits ChoKα, causes G1 arrest, ER stress, and cancer cell apoptosis.Formula:C26H44Br2N4Purity:99.54%Color and Shape:SolidMolecular weight:572.46Ref: TM-T27579
2mg43.00€5mg70.00€10mg92.00€25mg132.00€50mg200.00€100mg344.00€200mg505.00€1mL*10mM (DMSO)88.00€Lacutoclax
CAS:Lacutoclax (LP-108) is an orally active and selective Bcl-2 inhibitor with antitumor activity both in vivo and ex vivo，lymphoma and leukemia.Formula:C48H55ClN8O7SColor and Shape:SolidMolecular weight:923.52MK-2206 free base
CAS:MK-2206 free base is an allosteric Akt inhibitor that is both potent and selective, administered orally, exhibiting IC50 values of 8, 12, and 65 nM for Akt1,Formula:C25H21N5OPurity:98%Color and Shape:SolidMolecular weight:407.47Antitumor agent-60
CAS:Antitumor agent-60 inhibits growth by targeting RAS-RAF, binding CRAF (Kd: 721.3 nM), boosting p53/ROS, causing apoptosis, and arresting G2/M phase.Formula:C24H28O10SColor and Shape:SolidMolecular weight:508.54Cerivastatin
CAS:Cerivastatin is an HMG-CoA reductase inhibitor with anticancer and lipid-lowering effects and can be used to study primary hyperlipidemia.Formula:C26H34FNO5Purity:97.80% - 99.56%Color and Shape:SolidMolecular weight:459.55Ogremorphin
CAS:Ogremorphin (GPR68-IN-1) is a potent inhibitor of GPR68, exhibiting an EC50 of 170 nM.it is utilized in the study of autoimmune chronic inflammatory diseases [1Formula:C21H17N3OSPurity:99.65% - 99.65%Color and Shape:SolidMolecular weight:359.44NSC194598
CAS:NSC194598 is a p53 DNA-binding inhibitor, demonstrating an in vitro IC50 of 180 nM and an in vivo range of 2-40 μM.Formula:C20H19N3OColor and Shape:SolidMolecular weight:317.38GNE-900
CAS:GNE-900 is an ATP-competitive ChK1 inhibitor with selective and oral activity.GNE-900 inhibits ChKl and ChK2 with IC50 values of 0.0011 and 1.5 µM, respectivelyFormula:C23H21N5Purity:99.20%Color and Shape:SolidMolecular weight:367.45TC ASK 10
CAS:TC ASK 10 is a potent, selective and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1,IC50 = 14 nM). The IC50 value for ASK2 is 0.51 μM.Formula:C21H23Cl2N5OPurity:99.86%Color and Shape:SolidMolecular weight:432.35Ref: TM-T13099
1mg33.00€5mg86.00€10mg124.00€25mg236.00€50mg371.00€100mg532.00€200mg705.00€1mL*10mM (DMSO)95.00€NSC 689534
CAS:NSC 689534 forms a chelate with copper (Cu 2+), resulting in the NSC 689534/Cu 2+ complex, which is a potent inducer of oxidative stress and exhibits antitumor activity [1].Formula:C19H18N6SColor and Shape:SolidMolecular weight:362.45PDK4-IN-1 hydrochloride
CAS:PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4, IC50 value = 84 nM).Formula:C22H20ClN3O2Purity:99.67%Color and Shape:SolidMolecular weight:393.87Ref: TM-T12412L
1mg70.00€5mg150.00€10mg215.00€25mg358.00€50mg515.00€100mg707.00€200mg1,009.00€1mL*10mM (DMSO)165.00€Immunosuppressant-1
CAS:Immunosuppressant-1 (Compound 31) suppresses T-cell proliferation triggered by anti-CD3/anti-CD28 co-stimulation and demonstrates immunosuppressive effects,Formula:C14H12BrNO3Purity:98%Color and Shape:SolidMolecular weight:322.15RUNX-IN-2
CAS:RUNX-IN-2 (Compound Conjugate 3) covalently attaches to RUNX-binding sequences, preventing RUNX proteins from associating with their targets, thereby inhibitingFormula:C71H88Cl2N24O11Purity:98%Color and Shape:SolidMolecular weight:1524.52ST1074
CAS:ST1074, a dual inhibitor of CerS2 and CerS4, promotes apoptosis and is applicable in cancer research [1].Formula:C20H36ClNO3Purity:98%Color and Shape:SolidMolecular weight:373.96DC_AC50
CAS:"DC_AC50 inhibits Atox1/CCS to reduce cancer cell growth and prevent chemotherapy resistance."Formula:C17H12BrF2N3OSPurity:99.84% - 99.9%Color and Shape:SolidMolecular weight:424.26Ro 41-5253
CAS:Ro 41-5253 is a RARα antagonist with antitumor activity that inhibits the proliferation of ZR-75.1 estrogen receptor-positive breast cancer cells.Formula:C28H36O5SPurity:98%Color and Shape:SolidMolecular weight:484.65MS-177
CAS:MS-177 is a PROTAC EZH2 degrader that promotes cholangiocarcinoma growth through the EZH2-mediated WNT7B/β-catenin pathway.Formula:C48H55N11O8Color and Shape:SolidMolecular weight:914.02Ref: TM-T69771
1mg84.00€5mg177.00€10mg281.00€25mg557.00€50mg893.00€100mg1,341.00€1mL*10mM (DMSO)358.00€Ferroptocide
CAS:Ferroptocide is a thioredoxin inhibitor that induces iron death in cancer cells and can be used in breast cancer research.Formula:C30H36ClN3O7Color and Shape:SolidMolecular weight:586.08
