CymitQuimica logo
Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

Show 6 more subcategories

Found 5622 products of "Apoptosis"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • CHMFL-48
    Targetmol
    + Info

    CHMFL-48

    CAS:
    <p>CHMFL-48, an orally active inhibitor of BCR-ABL kinase, demonstrates efficacy against both the wild-type (wt) and various imatinib-resistant mutants. It exhibits potent inhibitory activity, with IC 50 values of 1 nM for the ABL wild-type and 0.8 nM for the ABL T315I mutant. CHMFL-48 operates by inhibiting the autophosphorylation of both wild-type and mutant BCR-ABL, affecting downstream signaling mediators including STAT5 and CRKL. This disruption leads to cell cycle arrest and triggers apoptosis. Given its properties, CHMFL-48 is a promising candidate for research on chronic myeloid leukemia (CML).</p>
    Formula:C31H30F3N7O
    Color and Shape:Solid
    Molecular weight:573.61

    Ref: TM-T89947

    10mg
    Discontinued
    50mg
    Discontinued
    Discontinued product
  • DETD-35
    Targetmol
    + Info

    DETD-35

    CAS:
    <p>DETD-35 is a promising chemical compound in anti-melanoma therapy, functioning as an inhibitor of the MEK-ERK, Akt, and STAT3 signaling pathways. It enhances cancer cell apoptosis (Apoptosis) and diminishes resistance to Vemurafenib in cancer cells. The compound exhibits IC 50 values of 2.7, 6.0, 3.9, 3.1, and 2.5 μM against melanoma cell lines B16-F10, MeWo, SK-MEL-2, A2058c, and A375c, respectively. DETD-35 offers significant potential for advancing research in melanoma treatment strategies.</p>
    Formula:C27H24O6
    Color and Shape:Solid
    Molecular weight:444.48

    Ref: TM-T89997

    10mg
    Discontinued
    50mg
    Discontinued
    Discontinued product