Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(91 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6039 products of "Apoptosis"
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WF-47-JS03
<p>WF-47-JS03: RET kinase inhibitor, crosses blood-brain barrier, 500x more selective for KDR, IC50: 1.7 nM in Ba/F3 cells, 5.3 nM in LC-2/ad lung cancer cells.</p>Formula:C30H38N6O2Color and Shape:SolidMolecular weight:514.66Samuraciclib
CAS:Samuraciclib (CT7001) is an oral CDK7 inhibitor with 41 nM IC50, notable for its high selectivity and potency against breast cancer cells.Formula:C22H30N6OColor and Shape:SolidMolecular weight:394.51Anticancer agent 44
Anticancer agent 44 induces apoptosis, is selective, cytotoxic to cancer cells, and minimally toxic to human lymphocytes.Formula:C22H13Cl2N3O5S2Color and Shape:SolidMolecular weight:534.39Sinulatumolin E
CAS:Sinulatumolin E, a terpenoid, inhibits TNF-α (IC 50: 3.6 μM); has anti-inflammatory properties.Formula:C15H22O2Color and Shape:SolidMolecular weight:234.33ASK1-IN-8
CAS:<p>ASK1-IN-8 (Compound 35) is an orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 value of 1.8 nM. In a mouse liver injury model induced by Acetaminophen, ASK1-IN-8 significantly reduces plasma alanine aminotransferase (ALT) levels, offering liver protection. This compound is useful for research in liver disease-related fields.</p>Formula:C26H32N8O2Color and Shape:SolidMolecular weight:488.585PIM-1/HDAC-IN-1
PIM-1/HDAC-IN-1 (4d): inhibits PIM-1 (IC50: 343.87nM), HDAC1 (63.65nM), HDAC6 (62.39nM); induces apoptosis in MCF-7 cells.Formula:C22H19N3O3Color and Shape:SolidMolecular weight:373.4EGFR-IN-161
CAS:EGFR-IN-161 (Compound DD-8) is a potent and reversible inhibitor of the L858R/T790M/C797S mutant EGFR kinase, with an IC50 value of 0.87 nM. EGFR-IN-161 effectively inhibits tumor cell apoptosis, G1 phase arrest, and migration.Formula:C33H36Cl2N8O2Color and Shape:SolidMolecular weight:647.597LL-Z 1640-4
CAS:A signal-specific JNK/p38 pathway and TAK 1 inhibitorFormula:C19H24O7Purity:98%Color and Shape:SolidMolecular weight:364.39STAT3-IN-9
STAT3-IN-9 hinders STAT3 at Tyr705, doesn't affect STAT1 Tyr701, induces apoptosis, and arrests cells in G2/M phase.Formula:C22H21N3O4Color and Shape:SolidMolecular weight:391.42Laulimalide
CAS:Microtubule stabilizer; halts cancer cell growth (IC50: 3-30 nM); arrests cells in prometaphase; prevents bipolar spindle formation.Formula:C30H42O7Color and Shape:SolidMolecular weight:514.65M3258
CAS:LMP7-IN-1 may used in the research of inflammatory and autoimmune diseases, neurodegenerative diseases, proliferative diseases and cancer, is an inhibitor ofFormula:C17H20BNO5Purity:98%Color and Shape:SolidMolecular weight:329.16EGFR-IN-62
EGFR-IN-62: IC50 of 10-242 nM for various EGFR mutations, blocks A549/H1975 cell cycle, induces apoptosis, and inhibits cell motility and proliferation.Formula:C30H33N9O2Color and Shape:SolidMolecular weight:551.64APD-94
CAS:APD-94 is a dual inhibitor targeting tubulin and Bmi-1. It disrupts the normal polymerization of tubulin and suppresses the expression of Bmi-1. This compound induces cell cycle arrest at the G2/M phase and triggers apoptosis, thereby inhibiting cancer cell proliferation. Additionally, APD-94 inhibits the growth of HT29 cell xenograft tumors in NOD/SCID mice and is applicable to colorectal cancer research.Formula:C18H17N3O4Color and Shape:SolidMolecular weight:339.345HSP90-IN-10
HSP90-IN-10 is a potent HSP90 inhibitor, targeting HCC1954 cells (IC50: 6 μM) and inducing apoptosis, sparing normal cells.Formula:C30H26FN3O6Color and Shape:SolidMolecular weight:543.54Bafilomycin C1
CAS:vacuolar H+-ATPases (V-ATPases) inhibitorFormula:C39H60O12Purity:98%Color and Shape:Light Tan SolidMolecular weight:720.89Topo I-IN-1
Topo I-IN-1 (14d) is a powerful Topo I inhibitor with antitumor effects and DNA intercalation, inducing apoptosis.Formula:C20H14BrN3O2Color and Shape:SolidMolecular weight:408.25PROTAC FKBP Degrader-3
CAS:PROTAC FKBP Degrader-3, with FKBP and VHL binding groups linked, is a potent FKBP degrader.Formula:C68H90N6O17SPurity:98%Color and Shape:SolidMolecular weight:1295.54Ph-Ph+
Ph-Ph+ is a dimerized phenanthroline derivative with antitumor, antibacterial, and antifungal effects.Formula:C24H17N4Color and Shape:SolidMolecular weight:361.42PARP10/15-IN-2
CAS:PARP10/15-IN-2 (Compound 8h) blocks PARP10/15, has IC50s: 0.15μM/0.37μM, cell-permeable, prevents apoptosis.Formula:C15H11FN2O3Color and Shape:SolidMolecular weight:286.26CDK4/6-IN-10
CDK4/6-IN-10: Oral CDK4 (IC50: 22 nM) & CDK6 (IC50: 10 nM) inhibitor with anti-cancer potential for MM research.Color and Shape:Solid
