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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 6039 products of "Apoptosis"

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  • Tubulin polymerization-IN-9
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    Tubulin polymerization-IN-9

    CAS:
    Tubulin-IN-9 inhibits tubulin (IC50: 1.82 μM), halts K562 cells in G2/M, induces apoptosis, and has anti-cancer effects.
    Formula:C19H19NO5Se
    Color and Shape:Solid
    Molecular weight:420.32

    Ref: TM-T62217

  • (S)-JDQ-443
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    (S)-JDQ-443

    CAS:
    <p>(S)-JDQ-443, an isomer of JDQ-443, is a selective, potent oral KRAS G12C inhibitor with antitumor properties.</p>
    Formula:C29H28ClN7O
    Color and Shape:Solid
    Molecular weight:526.03

    Ref: TM-T72971

  • Tubulin inhibitor 13
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    Tubulin inhibitor 13

    CAS:
    Tubulin inhibitor 13 (E27), IC50 16.1 μM, blocks tubulin polymerization, cancer cell migration, and invasion, induces apoptosis.
    Formula:C25H21N3O4
    Color and Shape:Solid
    Molecular weight:427.45

    Ref: TM-T62332

  • (S)-Purvalanol B
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    (S)-Purvalanol B

    CAS:
    (S)-Purvalanol B is the S enantiomer of Purvalanol B. Purvalanol B is an inhibitor of cyclin-dependent kinase(CDK) .
    Formula:C20H25ClN6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:432.9

    Ref: TM-T13454

  • MAPK-IN-5
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    MAPK-IN-5

    CAS:
    MAPK-IN-5 is a potent inhibitor of MAPK, with an IC50 value of 1.35 μM in HeLa cells. It induces ROS-mediated DNA damage and mitochondrial apoptosis (apoptosis) via the MAPK pathway. MAPK-IN-5 significantly inhibits colony formation in HeLa cells, reduces viable cell numbers, suppresses cell migration, and arrests the cell cycle at the G2/M phase. It is applicable in cervical cancer research.
    Formula:C30H29F3N6O4
    Color and Shape:Solid
    Molecular weight:594.58

    Ref: TM-T211815

  • BRD4/CK2-IN-1
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    BRD4/CK2-IN-1

    CAS:
    BRD4/CK2-IN-1 is a small-molecule inhibitor targeting BRD4 and CK2, inducing apoptosis and autophagy-related cell death.
    Formula:C29H30ClN5O5
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:564.03

    Ref: TM-T63991

  • NLRP3-IN-72
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    NLRP3-IN-72

    CAS:
    NLRP3-IN-72 (Compound 2) is a benzimidazole derivative. It exhibits anti-inflammatory and antioxidant properties, with an IC50 of 0.3 μM for NLRP3 IL-1β, a PD50 of 0.4 μM for protection against cell pyroptosis, and an EC50 of 0.6 μM for inducing HO-1.
    Formula:C19H20FN5O
    Color and Shape:Solid
    Molecular weight:353.393

    Ref: TM-T205657

  • FLT3-IN-32
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    FLT3-IN-32

    CAS:
    FLT3-IN-32 is a potent FLT3 inhibitor with high selectivity, effectively suppressing FLT3 activating mutations and inducing apoptosis. It demonstrates good tolerance in non-tumor-bearing mice. In NOD/SCID mice loaded with MV4-11 cells, FLT3-IN-32 exhibits outstanding antitumor efficacy, significantly extending mouse survival. FLT3-IN-32 is applicable for acute myeloid leukemia research.
    Formula:C28H29N5O5
    Color and Shape:Solid
    Molecular weight:515.56

    Ref: TM-T210598

  • Antitumor agent-76
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    Antitumor agent-76

    CAS:
    Antitumor agent-76 is a water-soluble, orally active, rapid-release prodrug of Triptolide that exhibits anticancer effects.
    Formula:C28H36ClNO10
    Color and Shape:Solid
    Molecular weight:582.04

    Ref: TM-T64111

  • RET-IN-10
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    RET-IN-10

    CAS:
    RET-IN-10: Potent RET inhibitor, may treat congenital megacolon and tumors (Patent WO2021135938A1, compound 18).
    Formula:C29H28N8OS
    Color and Shape:Solid
    Molecular weight:536.65

    Ref: TM-T63782

  • Topoisomerase II inhibitor 20 TFA
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    Topoisomerase II inhibitor 20 TFA

    TopoisomeraseII Inhibitor 20 TFA is a potent inhibitor of topoisomerase II with an IC50 of 0.98 µM. It can induce cell apoptosis and exhibits broad-spectrum anticancer activity.
    Formula:C24H24F5N5O4S
    Color and Shape:Solid
    Molecular weight:573.54

    Ref: TM-T201655

  • HP590
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    HP590

    CAS:
    HP590: potent oral STAT3 inhibitor, IC50=27.8 nM, blocks ATP, IC50=24.7 nM, hinders gastric cancer growth, triggers cell death.
    Formula:C29H24F6N4O3
    Color and Shape:Solid
    Molecular weight:590.52

    Ref: TM-T64182

  • CymitQuimica logo
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    ASCT2-IN-1

    CAS:
    ASCT2-IN-1 (compound 20k) is an inhibitor of ASCT2, demonstrating IC50 values of 5.6 μM in A549 cells and 3.5 μM in HEK293 cells. It induces apoptosis and inhibits tumor growth.
    Formula:C36H32Cl2N2O4
    Molecular weight:627.56

    Ref: TM-T209188

  • Ferroptosis-IN-6
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    Ferroptosis-IN-6

    CAS:
    Ferroptosis-IN-6 is an efficient ferroptosis inhibitor, protecting cells from cell death induced by ferroptosis inducers, and inhibiting STY-BODIPY oxidation.
    Formula:C15H17NO
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:227.3

    Ref: TM-T86417

  • FTO-IN-13
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    FTO-IN-13

    CAS:
    <p>FTO-IN-13 (compound 8t) is a potent FTO inhibitor with antiproliferative properties. It induces apoptosis (cell apoptosis) and reduces the expression of Bcl-2 and Caspase 3 active proteins. Additionally, FTO-IN-13 lowers the expression of MYC and CEBPA genes and demonstrates anticancer activity.</p>
    Formula:C18H12Br2N2O4
    Color and Shape:Solid
    Molecular weight:480.107

    Ref: TM-T204333

  • eIF4A-IN-1
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    eIF4A-IN-1

    CAS:
    eIF4A-IN-1 is an eIF4A inhibitor used in tumor research.
    Formula:C31H33N3O5
    Color and Shape:Solid
    Molecular weight:527.61

    Ref: TM-T212212

  • ADH-6
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    ADH-6

    CAS:
    ADH-6, a tripyridylamide, disrupts mutant p53 aggregates in cancer cells, reviving its function and inducing apoptosis.
    Formula:C29H36N8O9
    Color and Shape:Solid
    Molecular weight:640.64

    Ref: TM-T73533

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    PD-1/PD-L1-IN-15

    PD-1/PD-L1-IN-15 is a potent inhibitor of PD-1/PD-L1 (IC50: 60.1 nM) and has shown investigational potential for tumor immunotherapy.
    Formula:C32H30N4O3
    Color and Shape:Solid
    Molecular weight:518.61

    Ref: TM-T63614

  • Microtubulin-IN-1
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    Microtubulin-IN-1

    CAS:
    <p>Microtubulin-IN-1 (Compound 8g) is an inhibitor of microtubulin, targeting the colchicine-binding site to disrupt tubulin integrity and induce upregulation of p53 protein expression. It exhibits antiproliferative activity across various cancer cell lines, including NCI-H460, BxPC-3, and HT-29, with IC50 values of 2.4, 1.6, and 2.07 nM, respectively. Additionally, Microtubulin-IN-1 induces cell cycle arrest at the G2/M phase and apoptosis in NCI-H460 cells.</p>
    Formula:C25H21FN4O3
    Color and Shape:Solid
    Molecular weight:444.458

    Ref: TM-T206493

  • NVP-CGM097 sulfate
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    NVP-CGM097 sulfate

    CAS:
    NVP-CGM097 sulfate is a potent and selective inhibitor of MDM2 (hMDM2, IC50 of 1.7±0.1 nM).
    Formula:C38H49ClN4O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:757.34

    Ref: TM-T12273