Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(127 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(91 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5618 products of "Apoptosis"
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Apolizumab
CAS:<p>Apolizumab (Hu1D10) is a humanized antibody targeting HLA-DR beta-chain; induces apoptosis in CLL cells in vitro.</p>Color and Shape:LiquidMcl-1 inhibitor 3
CAS:<p>Mcl-1 inhibitor 3 shows good pharmacokinetic properties and excellent in vivo efficacy without toxicity.Mcl-1 inhibitor 3 is a highly potent and orally activate</p>Formula:C40H52ClF2N5O7SPurity:98%Color and Shape:SolidMolecular weight:820.39Topoisomerase IIα-IN-10
<p>TopoisomeraseIIα-IN-10 (Compound 13r) is a topoisomerase IIα inhibitor that binds to the active site of DNA when complexed with topoisomerase IIα. This binding is stabilized through interactions with DNA base pairs and amino acid residues. By intercalating into DNA, TopoisomeraseIIα-IN-10 induces apoptosis and disrupts the mitochondrial membrane potential in HCT116 cells, effectively inhibiting their growth with an IC50 of 4.37 μM. It is applicable for cancer research studies.</p>Formula:C32H27N3O3Color and Shape:SolidMolecular weight:501.575TTQ-SA
<p>TTQ-SA is a near-infrared spiraling aggregation-induced emitter capable of converting near-infrared light (NIR) into thermal energy, resulting in thermal damage and death of tumor cells. In cancer cells MF-7, TTQ-SA shows cell uptake and targeting capabilities. TTQ-SA binds with DNAzyme to inhibit the expression of the survivin gene, enhancing the sensitivity of tumor cells to photothermal therapy.</p>Formula:C78H53N7SColor and Shape:SolidMolecular weight:1120.37VEGFR-2-IN-61
<p>VEGFR-2-IN-61 (Compound 7b) is an inhibitor of VEGFR-2 with an IC50 of 2.83 µM. It effectively inhibits the proliferation of various cancer cells, including MCF-7 cells, with an IC50 of 2.12 µM. Additionally, VEGFR-2-IN-61 suppresses cell migration and induces oxidative stress and apoptosis in MCF-7 cells.</p>Formula:C27H25N5OColor and Shape:SolidMolecular weight:435.52PROTAC Bcl-xL ligand-1
<p>PROTAC Bcl-xL ligand-1 serves as a ligand targeting Bcl-xL, essential in synthesizing PROTACs [1].</p>Formula:C32H29IN4O4S2Color and Shape:SolidMolecular weight:724.63XY221
<p>XY221 (Compound 16o) selectively inhibits BRD4 BD2 with an IC50 of 5.8 nM. It demonstrates high selectivity for pan-BD2 and BRD4 BD2 domains, being 667 times more selective than for BRD4 BD1, and 9-32 times more selective than for BRD2/3/T BD2. XY221 can induce apoptosis in MV4-11 cells and exhibits anti-cancer activity.</p>Formula:C32H34FN3O5Color and Shape:SolidMolecular weight:559.628Dual Galectin-3/EGFR-IN-1
<p>Dual Galectin-3/EGFR-IN-1 (Compound 29) is a dual inhibitor targeting Galectin-3 and EGFR, with dissociation constants (KD) of 52.29 μM and 3.31 μM, respectively. It inhibits TGF-β-induced hepatic stellate cell (HSC) activation, induces apoptosis in LX-2 cells, and shows antifibrotic activity in the liver.</p>Formula:C32H41N7O10Color and Shape:SolidMolecular weight:683.709AZD5153
CAS:AZD5153 is an orally active and selective BET/BRD4 bromodomain inhibitor with an IC50 value of 1.7nM for BRD4.Formula:C25H33N7O3Purity:99.25%Color and Shape:SolidMolecular weight:479.57Antitumor agent-36
<p>Antitumor agent-36: potent anti-cancer; causes DNA damage, triggers apoptosis, enhances immune response by upregulating T cells.</p>Formula:C32H30Cl2N2O6PtColor and Shape:SolidMolecular weight:804.58Pim-1 kinase inhibitor 4
<p>Pim-1 kinase inhibitor 4 is a potent Pim-1 kinase inhibitor with an IC50 value of 17.01 nM.Pim-1 kinase inhibitor 4 also possesses antioxidant activity and</p>Formula:C19H12ClN3OPurity:97.72%Color and Shape:SolidMolecular weight:333.77CTP-347
CAS:CTP-347, a deuterated version of paroxetine, is potentially the best non-hormonal drug in its class for the treatment of hot flashes.Formula:C19H20FNO3Molecular weight:331.38BOC-D-FMK
CAS:<p>Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 μM).</p>Formula:C11H18FNO5Purity:97.02%Color and Shape:SolidMolecular weight:263.26Giloralimab
CAS:<p>Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.</p>Purity:95.6% (SDS-PAGE); 95.1% (SEC-HPLC) - 95.6% (SDS-PAGE); 95.1% (SEC-HPLC)Color and Shape:LiquidUrelumab
CAS:<p>"Urelumab (BMS-66513), a humanized IgG4 mAb CD137 agonist, boosts T-cell/NK cell-mediated cytotoxicity and anti-tumor activity."</p>Purity:97.70%Color and Shape:LiquidMolecular weight:145.90 kDaHKB99
CAS:<p>HKB99 suppresses NSCLC growth, metastasis, and overcomes erlotinib resistance.</p>Formula:C23H18N2O6SPurity:97.35% - 97.35%Color and Shape:SolidMolecular weight:450.465α-dihydro Levonorgestrel
CAS:<p>5α-dihydro Levonorgestrel is a metabolite of the synthetic progestin levonorgestrel .</p>Formula:C21H30O2Color and Shape:SolidMolecular weight:314.469Tralokinumab
CAS:<p>Tralokinumab: human IgG4 monoclonal antibody, blocks IL-13, may treat atopic dermatitis.</p>Purity:SDS-PAGE:95% SEC-HPLC:99.99%Color and Shape:LiquidMolecular weight:144.14 kDaOpucolimab
CAS:<p>Opucolimab is a human antibody targeting PD-L1, used in advanced solid tumor research and antibody-drug conjugate synthesis.</p>Color and Shape:LiquidDaporinad hydrochloride
CAS:Daporinad hydrochloride (FK 866 hydrochloride) is a NAMPT inhibitor with antitumor and antiangiogenic activity that induces apoptosis in tumor cells.Formula:C24H30ClN3O2Purity:98.99%Color and Shape:SolidMolecular weight:427.97
