Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5600 products of "Apoptosis"
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SSE1806
<p>SSE1806, a podophyllotoxin derivative (a natural antimitotic agent), functions as a microtubule/tubulin inhibitor, exhibiting potent anticancer and</p>Formula:C21H18N2O5Color and Shape:SolidMolecular weight:378.38MY-943
<p>MY-943, a potent inhibitor of tubulin polymerization and LSD1, exhibits anticancer properties by inducing G2/M phase arrest, promoting apoptosis, and</p>Formula:C30H36N4O6S2Color and Shape:SolidMolecular weight:612.763-Hydroxyterphenyllin
CAS:<p>3-Hydroxyterphenyllin from A. candidus is a fungal compound with antioxidant, anticancer, antibacterial, and antiviral effects.</p>Formula:C20H18O6Color and Shape:SolidMolecular weight:354.35Petromurin C
CAS:<p>Petromurin C, a bis-indolyl benzenoid from P. muricatus, is cytotoxic to NS-1 cells (IC50=33μg/ml) and active against T. foetus (IC50=100μg/ml).</p>Formula:C26H24N2O5Color and Shape:SolidMolecular weight:444.487eIF4E-IN-5
<p>eIF4E-IN-5 (Compound 6n) is a cell-permeable eIF4E inhibitor that binds to capped mRNA, thereby inhibiting cap-dependent translation [1].</p>Formula:C30H39Cl2N6O8PColor and Shape:SolidMolecular weight:713.55Terrein
CAS:<p>Terrain (NSC 291308), a fungal metabolite, reduces age-related inflammation via Nrf2/ERK1/2/HO-1 and inhibits IL-6 in human fibroblasts.</p>Formula:C8H10O3Color and Shape:SolidMolecular weight:154.16PROTAC NCOA4 degrader-1
<p>PROTACNCOA4 degrader-1 (Compound V3) is a PROTAC-based degrader of NCOA4, exhibiting a DC50 of 3 nM in HeLa cells. Besides acting as a ferroptosis inhibitor, this compound effectively reduces the levels of NCOA4 and decreases intracellular ferrous (Fe2+) levels. Moreover, PROTACNCOA4 degrader-1 ameliorates liver damage in a CCl4-induced acute liver injury model.</p>Color and Shape:Odour SolidHuman PD-L1 inhibitor II
CAS:<p>Human PD-L1 inhibitor II is a potent PD-L1 inhibitor with anti-cancer activity.</p>Formula:C103H151N25O30Color and Shape:SolidMolecular weight:2219.486Human PD-L1 inhibitor I
CAS:<p>Human PD-L1 inhibitor I, a peptide, blocks PD-L1/PD-1 interaction with 3.39 μM affinity.</p>Formula:C110H152N26O32Color and Shape:SolidMolecular weight:2350.576CDC20-IN-2
<p>CDC20-IN-2 (14c) is an inhibitor of Cdc20 with a KD of 7.65 μM, inducing G2/M phase arrest, promoting DNA damage accumulation, and stabilizing key substrates such as Cyclin B1 and Bim. This leads to enhanced apoptosis, as well as inhibition of tumor cell proliferation and migration.</p>Color and Shape:Odour SolidFOXO4-DRI
CAS:<p>FOXO4-DRI: a peptide blocking FOXO4/p53 interaction; induces senescent cells' apoptosis.</p>Formula:C228H388N86O64Color and Shape:SolidMolecular weight:5358.06PDE4B-IN-4
<p>PDE4B-IN-4 is an inhibitor of PDE4B (IC50: 2.82 nM) and TNF-α (IC50: 7.20 nM). It demonstrates anti-inflammatory properties by reducing neutrophilia in a mouse model of lipopolysaccharide (LPS)-induced sepsis.</p>Formula:C26H27N5O5Color and Shape:SolidMolecular weight:489.52Antitumor agent-145
CAS:Compound Ir5 (Antitumor agent-145) serves as a tumor inhibitor characterized by significant fluorescence and mitochondrial targeting. It promotes anti-cancer activity by inducing necroptosis and stimulating the necroptosis-related immune response [1].Formula:C44H34IrN5OSColor and Shape:SolidMolecular weight:873.06XIAP BIR2/BIR2-3 inhibitor-3
CAS:<p>XIAP BIR2/BIR2-3 Inhibitor-3 functions as a dual inhibitor targeting both BIR2 and BIR2-3 domains, exhibiting potent activity with IC50 values below 1 nM. This compound is utilized in cancer research [1].</p>Formula:C86H106N18O16S2Color and Shape:SolidMolecular weight:1712Atibuclimab
CAS:<p>Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region.</p>Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:145.28 kDaGSK-1070916
CAS:<p>GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM.</p>Formula:C30H33N7OPurity:99.73%Color and Shape:SolidMolecular weight:507.634-Nitrothalidomide
CAS:<p>4-Nitrothalidomide is a modified form of thalidomide that inhibits the growth and proliferation of HUVEC cells and is commonly used in the synthesis of pomalidomide, which has anticancer potential.</p>Formula:C13H9N3O6Purity:99.94%Color and Shape:SolidMolecular weight:303.23MMRi62
CAS:<p>MMRi62, a MDM2-MDM4 inhibitor, induces ferroptosis and autophagy in PDAC, degrades FTH1 and mutant p53, and inhibits KRAS/TP53 mutant PDAC in mice.</p>Formula:C21H15Cl2N3OPurity:99.87%Color and Shape:SoildMolecular weight:396.27IRF1-IN-2
CAS:<p>IRF1-IN-2 is a small molecule IRF1 inhibitor that suppresses pyroptosis, protecting against radiation-induced skin damage.</p>Formula:C18H20N2O4SPurity:99.85%Color and Shape:SolidMolecular weight:360.43FL118
CAS:<p>FL118 is a novel survivin inhibitor that inhibits cancer stem cell-like properties.FL118 is a novel camptothecin analog with anticancer activity that inhibits</p>Formula:C21H16N2O6Purity:98.99%Color and Shape:SoildMolecular weight:392.36
