CymitQuimica logo
Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

Show 6 more subcategories

Found 5593 products of "Apoptosis"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • CymitQuimica logo
    Targetmol
    + Info

    TRBP-IN-1

    <p>TRBP-IN-1 (Compound 13j) is an orally active inhibitor of TAR RNA-binding protein 2 (TRBP) with an IC50 of 12.72 μM. It exhibits significant anti-hepatocellular carcinoma (HCC) activity, effectively suppressing proliferation and metastasis of HCC cells [HCCLM3 cells (IC50: 18.96 μM) and SK-Hep-1 cells (IC50: 16.45 μM)]. TRBP-IN-1 modulates miRNA biosynthesis by targeting TRBP, inhibiting the expression of oncogenic miRNAs. It induces apoptosis and pyroptosis in HCC cells by decreasing miRNA levels. TRBP-IN-1 is suitable for research on targeted HCC therapy.</p>
    Formula:C25H23F3N2O5S
    Color and Shape:Solid
    Molecular weight:520.12798

    Ref: TM-T207594

  • Boanmycin
    Targetmol
    + Info

    Boanmycin

    CAS:
    <p>Boanmycin, an antibiotic exhibiting antitumor activity, induces cellular senescence and apoptosis [1] [2] [3].</p>
    Formula:C60H96N20O21S2
    Color and Shape:Solid
    Molecular weight:1497.66

    Ref: TM-T74590

  • PCC0208017
    Targetmol
    + Info

    PCC0208017

    CAS:
    <p>PCC0208017 is an inhibitor of MARK3 and MARK4 with IC50s of 1.8 and 2.01 nM. PCC0208017 disrupts microtubule dynamics and displays potent antitumor activity.</p>
    Formula:C19H20F3N7
    Purity:99.48%
    Color and Shape:Solid
    Molecular weight:403.4

    Ref: TM-T40249

  • UZH1a
    Targetmol
    + Info

    UZH1a

    CAS:
    <p>UZH1a: METTL3 inhibitor, IC50 280 nM, used for epitranscriptomic modulation and has antitumor properties.</p>
    Formula:C32H42N6O3
    Color and Shape:Soild
    Molecular weight:558.71

    Ref: TM-T37448

  • AKN-028
    Targetmol
    + Info

    AKN-028

    CAS:
    <p>AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.</p>
    Formula:C17H14N6
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:302.33

    Ref: TM-T38562

  • P53R3
    Targetmol
    + Info

    P53R3

    CAS:
    <p>P53R3 is a potent reactivator of p53, effectively restoring sequence-specific DNA binding to several p53 hot spot mutants, namely p53 R175H, p53 R248W, and p53</p>
    Formula:C32H35Cl2N5O2
    Purity:98.8%
    Color and Shape:Solid
    Molecular weight:592.56

    Ref: TM-T41068

  • CymitQuimica logo
    Targetmol
    + Info

    PROTAC 20S proteasome subunit β5 degrader 1

    <p>PROTAC 20S proteasome subunit β5 degrader 1 (compound 12f) serves as a targeted degrader of the 20S proteasome subunit β5, exhibiting a DC50 value of 0.11 μM in FaDu cells. This compound disrupts the cell cycle and promotes apoptosis (apoptosis), while inhibiting cell proliferation and migration in both FaDu and KM3/BTZ cells. It is applicable for research into resistance to Bortezomib in pharyngeal carcinoma and multiple myeloma.</p>
    Color and Shape:Odour Solid

    Ref: TM-T200715

  • CPTH2 (hydrochloride) (357649-93-5 free base)
    Targetmol
    + Info

    CPTH2 (hydrochloride) (357649-93-5 free base)

    CAS:
    <p>CPTH2 is an inhibitor of the HAT activity of Gcn5.</p>
    Formula:C14H15Cl2N3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:328.26

    Ref: TM-T22693

  • CymitQuimica logo
    Targetmol
    + Info

    Pamrevlumab

    CAS:
    <p>FG-3019 (Pamrevlumab), a human antibody, targets CTGF, potentially treating idiopathic pulmonary fibrosis.</p>
    Purity:100% (SEC-HPLC) - 95%
    Color and Shape:Liquid

    Ref: TM-T76804

  • PF-543
    Targetmol
    + Info

    PF-543

    CAS:
    <p>PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.</p>
    Formula:C27H31NO4S
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:465.6

    Ref: TM-T6085

  • Cefatrizine
    Targetmol
    + Info

    Cefatrizine

    CAS:
    <p>Cefatrizine inhibits eEF-2 kinase, affecting apoptosis, autophagy, and ER stress in cancers.</p>
    Formula:C18H18N6O5S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:462.5

    Ref: TM-T26973

  • PROTAC FLT-3 degrader 1
    Targetmol
    + Info

    PROTAC FLT-3 degrader 1

    CAS:
    <p>PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD)(IC50 0.6 nM),with anti-proliferative activity.</p>
    Formula:C52H61N9O9S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1020.23

    Ref: TM-T12555

  • CymitQuimica logo
    Targetmol
    + Info

    FLT3/HDAC-IN-1

    <p>FLT3/HDAC-IN-1 is a dual inhibitor targeting FLT3 and HDAC, with IC50 values of 30.4 nM for FLT3 and 52.4, 14.7 nM for HDAC1/3, respectively. It induces apoptosis in MV-4-11 cells and exhibits antiproliferative effects against BaF3 cells transformed by FLT3 mutations. FLT3/HDAC-IN-1 is useful for research on refractory solid tumors and hematological malignancies.</p>
    Color and Shape:Odour Solid

    Ref: TM-T200434

  • CymitQuimica logo
    Targetmol
    + Info

    FD2157

    <p>FD2157, a photosensitive PI3K inhibitor, exhibits inhibitory IC50 values of 43 nM for PI3Kα, 83 nM for PI3Kβ, 84 nM for PI3Kγ, and 14 nM for PI3Kδ.</p>
    Formula:C27H21ClN6O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:625.01

    Ref: TM-T79669

  • CymitQuimica logo
    Targetmol
    + Info

    KSRP-IN-1

    <p>KSRP-IN-1 (compound 8) acts as an inhibitor of KSRP, inducing cell cycle arrest and apoptosis (Apoptosis). This compound demonstrates antitumor activity.</p>
    Color and Shape:Odour Solid

    Ref: TM-T200555

  • KB02-SLF
    Targetmol
    + Info

    KB02-SLF

    <p>KB02-SLF, a molecular glue, degrades nuclear FKBP12 by modifying E3 ligase DCAF16 and extends protein degradation.</p>
    Formula:C50H65ClN4O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:949.52

    Ref: TM-T18061

  • Fosbretabulin [free base]
    Targetmol
    + Info

    Fosbretabulin [free base]

    CAS:
    <p>Fosbretabulin is a natural cis-stilbene that interferes with cellular tubulin dynamics and selectively destroys tumor blood vessels.</p>
    Formula:C18H21O8P
    Color and Shape:Solid
    Molecular weight:396.33

    Ref: TM-T31857

  • Thalidomide-O-C8-NH2
    Targetmol
    + Info

    Thalidomide-O-C8-NH2

    CAS:
    <p>Thalidomide-O-C8-NH2 is a synthetic cereblon ligand &amp; PROTAC linker, serving as an E3 ligase ligand-linker.</p>
    Formula:C21H27N3O5
    Color and Shape:Solid
    Molecular weight:401.463

    Ref: TM-T39376

  • CymitQuimica logo
    Targetmol
    + Info

    Anticancer agent 106

    <p>Compound 106 (compound 10ic) induces apoptosis in B16-F10 melanoma cells and potently inhibits metastatic nodules in mouse models of lung metastatic melanoma,</p>
    Formula:C26H25N3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:475.56

    Ref: TM-T78958

  • CQ-Mito
    Targetmol
    + Info

    CQ-Mito

    <p>CQ-Mito, a derivative of CQ, demonstrates excellent phototherapeutic efficacy with a PI value of 167. This compound induces cell death through mechanisms such as apoptosis and ferroptosis. It mediates mitochondrial dysfunction, characterized by alterations in mitochondrial morphology and loss of MMP. Additionally, CQ-Mito effectively inhibits tumor growth in 3D multicellular tumor spheroid models.</p>
    Formula:C45H42BrN6O4P
    Color and Shape:Solid
    Molecular weight:841.73

    Ref: TM-T201498