Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(17 products)
- Survivin(14 products)
- TNF(90 products)
- c-RET(61 products)
- p53(63 products)
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Found 6170 products of "Apoptosis"
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PTD-p65-P1 Peptide TFA
Ptd-p65-p1 Peptide TFA inhibits NF-kappaB, has a cell-penetrating antennapedia sequence, and selectively blocks NF-kappaB activation.
Formula:C170H276F3N57O46SPurity:98%Color and Shape:SolidMolecular weight:3943.52Tubulin inhibitor 34
Tubulin Inhibitor 34 (compound b5), a potent anticancer agent, inhibits tubulin polymerization and induces G2/M arrest and apoptosis.Formula:C21H22N4O3SColor and Shape:SolidMolecular weight:410.492,5-Dimethylcyclohexa-2,5-diene-1,4-dione
CAS:2,5-Dimethylcyclohexa-2,5-diene-1,4-dione inhibits the viability of HL60 and K562 cells and exhibits antibacterial and anticancer properties.Formula:C8H8O2Purity:99.80%Color and Shape:SolidMolecular weight:136.15Apoptosis inducer 37
Apoptosis inducer37 (Derivative 10) is an agent that induces apoptosis and exhibits anticancer properties by causing cell cycle arrest at the S-G2/M phase and promoting cell apoptosis. It significantly inhibits HCT116, SKOV3, and HepG2 cancer cells with IC50 values of 24.98 μM, 26.15 μM, and 23.09 μM, respectively. Apoptosis inducer37 demonstrates antitumor activity and can be utilized in ovarian cancer research.Formula:C27H37BrN2O4SColor and Shape:SolidMolecular weight:564.16574JPS014 TFA
JPS014 TFA, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDACFormula:C48H60F3N7O9SPurity:98%Color and Shape:SolidMolecular weight:968.09Aspidin BB
CAS:Aspidin BB, a phloroglucinol from Dryopteris, inhibits cancer by causing cell cycle arrest and apoptosis in HO-8910 cells.Formula:C25H32O8Color and Shape:SolidMolecular weight:460.52WEHI-3773
WEHI-3773 is an inhibitor of the interaction between VDAC2 and either BAK or BAX. It prevents BAX-mediated apoptosis (Apoptosis) by blocking the recruitment of BAX to the mitochondria through VDAC2. Conversely, WEHI-3773 promotes BAK-mediated apoptosis (Apoptosis) by limiting VDAC2's inhibitory sequestration of BAK. This compound shows promise for research in the field of cancer therapy.Color and Shape:Odour Solidc-JUN peptide
CAS:Peptide from c-Jun (33-57) blocks JNK binding, inhibits phosphorylation, upregulates p21, and induces HeLa cell apoptosis.
Formula:C121H210N36O34SPurity:98%Color and Shape:SolidMolecular weight:2743.55Pralnacasan
CAS:Pralnacasan blocks IL-18, IL-1β, IFN-γ. It’s a potent oral enzyme inhibitor with use in arthritis therapy (Ki: 1.4 nM).Formula:C26H29N5O7Purity:98%Color and Shape:SolidMolecular weight:523.54NCT-58
CAS:NCT-58 is a potent HSP90 inhibitor that blocks Akt, downregulates HER family, and induces apoptosis in HER2+ breast cancer without triggering HSR.Formula:C27H34N2O5Purity:99.55%Color and Shape:SolidMolecular weight:466.57Ref: TM-T9996
2mg43.00€5mg80.00€10mg119.00€25mg245.00€50mg394.00€100mg627.00€200mg842.00€1mL*10mM (DMSO)197.00€4-oxo-27-TBDMS Withaferin A
CAS:4-oxo-27-TBDMS Withaferin A, a withaferin A derivative, is an anticancer agent cytotoxic to A2780, not A2780/CP70.Formula:C34H50O6SiColor and Shape:SolidMolecular weight:582.853Dehydroaltenusin
CAS:Dehydroaltenusin is a selective eukaryotic DNA polymerase α inhibitor and a type of antibiotic produced by a fungus (IC50: 0.68 μM).Formula:C15H12O6Purity:98%Color and Shape:SolidMolecular weight:288.255VEGFR-2-IN-36
VEGFR-2-IN-36 (compound 15) serves as a potent VEGFR-2 inhibitor, exhibiting an IC50 value of 0.067 μM, and acts as an apoptosis inducer with demonstratedFormula:C24H23N7O5Purity:98%Color and Shape:SolidMolecular weight:489.48Thalidomide-O-PEG4-azide
CAS:Thalidomide-O-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].Formula:C23H29N5O9Purity:98%Color and Shape:SolidMolecular weight:519.5Aromatase-IN-5
Aromatase-IN-5 (Compound 10) is a potent inhibitor of aromatase with an IC50 value of 0.06 μM. It effectively blocks estrogen production and inhibits the proliferation of breast cancer cell lines such as MCF-7, arresting the cell cycle in the G1 phase and inducing apoptosis. Aromatase-IN-5 shows promise for breast cancer research.Color and Shape:Odour SolidThalidomide-5,6-Cl
CAS:Thalidomide-5,6-Cl is a cereblon ligand derivative that recruits CRBN protein and forms PROTACs with a linker.Formula:C13H8Cl2N2O4Color and Shape:SolidMolecular weight:327.12P1D-34
P1D-34 is a Pin1 PROTAC degrader with a DC50 value of 177 nM. It downregulates Pin1 substrate proteins, including Cyclin D1, Rb, Mcl-1, Akt, and c-Myc. Additionally, P1D-34 exhibits antiproliferative activity across various acute myeloid leukemia (AML) cell lines and induces DNA damage and apoptosis by generating reactive oxygen species (ROS).Color and Shape:Odour SolidCALP1
CAS:Cell-permeable CaM agonist; activates phosphodiesterase, binds to Ca2+ channels, inhibits cytotoxicity (IC50=52μM), protects cells, reduces inflammation.Formula:C40H75N9O10Purity:98%Color and Shape:SolidMolecular weight:842.09Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2
CAS:Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate compound that combines a Thalidomide-based cereblon ligand and a linker, which is commonly
Formula:C25H34N4O9Purity:98%Color and Shape:SolidMolecular weight:534.566Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA
CAS:Arg-Gly-Asp-D-Phe-Val (TFA) has anti-tumor activity and is an inhibitor of integrin αvβ3.Formula:C28H39F3N8O9Purity:98%Color and Shape:SolidMolecular weight:688.662
