Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(17 products)
- Survivin(14 products)
- TNF(91 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6170 products of "Apoptosis"
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DB2115 tertahydrochloride
CAS:DB2115 (tertahydrochloride) inhibits PU.1, key in leukemia; potential for cancer research.
Formula:C32H34Cl4N8O2Color and Shape:SolidMolecular weight:704.48XZ338
XZ338 is a highly selective degrader targeting BCL-XL without degrading BCL-2. It exhibits an IC50 value of 3.7 nM against MOLT-4 cells and possesses antiproliferative properties, making it useful for cancer research.Color and Shape:Odour SolidMcl-1 antagonist 1
CAS:Mcl-1 antagonist 1 is a Mcl-1 protein antagonist.Formula:C41H54ClF2N5O8SPurity:98%Color and Shape:SolidMolecular weight:850.42VEGFR-2-IN-64
VEGFR-2-IN-64 (Compound 28) is an inhibitor of VEGFR2 with an IC50 of 27.8 nM. It suppresses the proliferation of cancer cells A549, T-47D, and Caco-2, exhibits anti-migration and anti-colony formation activities in T-47D cells, and induces apoptosis in T-47D cells.Formula:C72H123N9O6Color and Shape:SolidMolecular weight:1210.8MPT0B014
CAS:MPT0B014 is a potent tubulin polymerization inhibitor. MPT0B014 can induce cancer cell apoptosis.
Formula:C19H17NO4Purity:99.52%Color and Shape:SolidMolecular weight:323.34Thalidomide-O-C7-acid
CAS:Thalidomide-O-C7-acid: A cereblon ligand from Thalidomide linked via a PROTAC-used linker.Formula:C21H24N2O7Color and Shape:SolidMolecular weight:416.43EGCG-4″-sulfate
CAS:EGCG-4″-sulfate, a predominant polyphenol in green tea, demonstrates notable anticancer, antioxidant, and anti-inflammatory effects, particularly againstFormula:C22H18O14SColor and Shape:SolidMolecular weight:538.43Pamlectabart
Pamlectabart is a humanised antibody targeting TNFRSF17/BCMA, (ADC) Pamlectabart tismanitin multiple myeloma.Purity:95%Color and Shape:LiquidMolecular weight:145.20 kDaWaltonitone
CAS:Waltonitone is a natural ursane-type pentacyclic triterpene isolated from Gentian waltonii Burkill.Formula:C30H48O2Purity:98%Color and Shape:SolidMolecular weight:440.7FPR1 antagonist 2
Compound 25b, an FPR1 antagonist, exhibits potent inhibition of the formyl peptide receptor 1 with an IC50 of 70 nM.Formula:C25H25F3O5Color and Shape:SolidMolecular weight:462.461,8-Cineole
CAS:Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.Formula:C10H18OPurity:97.44% - 97.44%Color and Shape:SolidMolecular weight:154.25CNDAC hydrochloride
CAS:CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.Formula:C10H13ClN4O4Purity:99.45%Color and Shape:SolidMolecular weight:288.69Ref: TM-T13621
1mg108.00€5mg259.00€10mg404.00€25mg578.00€50mg745.00€100mg1,189.00€200mg1,603.00€1mL*10mM (DMSO)236.00€Thalidomide-NH-C10-COOH
Compound 6b is a synthetic Thalidomide-VHL E3 ligase-linker for PROTACs.Formula:C24H31N3O6Purity:98%Color and Shape:SolidMolecular weight:457.52PPIA-IN-1
PPIA-IN-1 (Compound 20b) is an inhibitor of peptidyl-prolyl isomerase A (PPIA) with a KD of 0.52 μM. It demonstrates antiproliferative activity across various cancer cell lines, including an IC50 of 0.69 μM in HCT116 cells, induces cell cycle arrest at the G0/G1 phase, and exhibits antimetastatic effects in HCT116 cells. PPIA-IN-1 elevates ROS levels, causing DNA damage, ER stress, and mitochondrial dysfunction, and induces apoptosis in HCT116 cells via the MAPK pathway. Additionally, PPIA-IN-1 shows antitumor activity in a CT26 xenograft mouse model.Formula:C23H21Cl2FN4O7Color and Shape:SolidMolecular weight:555.34Bcl-2-IN-5
CAS:Bcl-2-IN-5: BCL-2 inhibitor, IC50: 0.12 nM (wt), 0.14 nM (D103Y), 0.22 nM (G101V); Cell growth IC50: 0.2 nM, 0.44 nM (RS4;11).Formula:C55H63FN8O8SColor and Shape:SolidMolecular weight:1015.2Thalidomide-O-amido-C3-NH2
CAS:Thalidomide-derived cereblon ligand linked to a PROTAC technology linker, Thalidomide-O-amido-C3-NH2, is a synthetic E3 ligase ligand-linker.Formula:C18H20N4O6Color and Shape:SolidMolecular weight:388.37Thalidomide-O-amido-C4-N3
CAS:Thalidomide-O-amido-C4-N3 (Cereblon Ligand-Linker Conjugates 4) is an E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand andFormula:C19H20N6O6Purity:97.01%Color and Shape:SolidMolecular weight:428.4Mcl-1 inhibitor 16
Mcl-1 Inhibitor 16 (Compound 9), a platinum-based mitochondrial-targeting agent, inhibits Mcl-1 and induces Bax/Bak-dependent apoptosis in cancer cells.Formula:C25H29Cl2N3PtColor and Shape:SolidMolecular weight:637.51HG-7-85-01
CAS:HG-7-85-01 is a novel ATP-competitive and type II tyrosine kinase inhibitor targeting both wild-type and watchman mutant BCR-ABL, PDGFRα, Kit, and Src kinases.Formula:C31H31F3N6O2SPurity:98.08%Color and Shape:SolidMolecular weight:608.68GPLGIAGQ
CAS:GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting.Formula:C31H53N9O10Purity:98%Color and Shape:SolidMolecular weight:711.81
