Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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Human PD-L1 inhibitor II
CAS:<p>Human PD-L1 inhibitor II is a potent PD-L1 inhibitor with anti-cancer activity.</p>Formula:C103H151N25O30Color and Shape:SolidMolecular weight:2219.486Necroptosis-IN-4
<p>Necroptosis-IN-4 is an effective inhibitor of necroptosis, specifically targeting RIP kinase 1 (RIPK1) without inhibitory activity against RIPK3. It exhibits weak inhibitory effects on VEGFR1/2 and PDGFR-α.</p>Color and Shape:Odour SolidEGFR T790M/L858R-IN-2
<p>EGFRT790M/L858R-IN-2: selective inhibitor, IC50: 3.5 nM (mutant), 1290 nM (WT); reduces p-EGFR/AKT/ERK1/2, triggers apoptosis, G1 arrest, anti-cancer.</p>Formula:C28H28FN7OColor and Shape:SolidMolecular weight:497.575-Fluorouracil-13C,15N2
CAS:<p>5-Fluorouracil-13C,15N2 is a standard for quantifying 5-fluorouracil via GC/LC-MS and blocks DNA synthesis, causing cell apoptosis.</p>Formula:C4H3FN2O2Color and Shape:SolidMolecular weight:133.057Human PD-L1 inhibitor I
CAS:<p>Human PD-L1 inhibitor I, a peptide, blocks PD-L1/PD-1 interaction with 3.39 μM affinity.</p>Formula:C110H152N26O32Color and Shape:SolidMolecular weight:2350.576Manelimab
CAS:<p>Manelimab is a monoclonal antibody that inhibits programmed death-ligand 1 ( PD-L1 ) [1] .</p>Color and Shape:LiquidTD52 dihydrochloride
<p>TD52 dihydrochloride, an Erlotinib derivative, inhibits protein phosphatase 2A and induces apoptosis in TNBC by disrupting CIP2A/PP2A/p-Akt signaling.</p>Formula:C24H18Cl2N4Purity:97.23%Color and Shape:SoildMolecular weight:433.33Dimethachlor
CAS:<p>Dimethachlor is a pesticide and herbicide used in wetland areas.</p>Formula:C13H18ClNO2Color and Shape:SolidMolecular weight:255.74G-Glu-Val
CAS:<p>G-Glu-Val (γ-glutamyl-L-valine, H-Glu-Val -OH), a flavour-regulating dipeptide, is a major contributor to "mellow".</p>Formula:C10H18N2O5Color and Shape:SolidMolecular weight:246.26Kusunokinin
<p>Kusunokinin is a useful organic compound for research related to life sciences and the catalog number is T124612.</p>Formula:C21H22O6Color and Shape:SolidMolecular weight:370.401Z-Asp-CH2-DCB
CAS:<p>Z-Asp-CH2-DCB is an irreversible inhibitor of broad spectrum caspase.</p>Formula:C20H17Cl2NO7Purity:99.08%Color and Shape:SolidMolecular weight:454.26CYP51/PD-L1-IN-4
<p>CYP51/PD-L1-IN-4 (compound 14a-2) is a potent dual-target inhibitor of CYP51/PD-L1, displaying IC50 values of 0.17 and 0.021 μM, respectively.</p>Formula:C27H28N4O3Color and Shape:SolidMolecular weight:456.54RPS6-IN-1
<p>RPS6-IN-1 (Compound 22o) inhibits cell migration and induces apoptosis (increasing the expression of Bax, p53, cleaved-caspase 3, and cleaved-PARP). It reduces mitochondrial membrane potential and activates autophagy (Autophagy) through the PI3K-Akt-mTOR signaling pathway, damaging mitochondria and lysosomes within the cell and causing endoplasmic reticulum stress. RPS6-IN-1 also inhibits the phosphorylation of RPS6. Notably, RPS6-IN-1 is a low systemic toxicity anticancer agent.</p>Color and Shape:Odour SolidAntagonist G TFA
<p>Potent vasopressin blocker, Antagonist G TFA also mildly inhibits GRP & Bradykinin, triggers AP-1, enhances chemo response.</p>Formula:C51H67F3N12O8SColor and Shape:SolidMolecular weight:1065.21ASK1-IN-4
CAS:<p>ASK1-IN-4 is an ASK1 inhibitor, IC50 = 0.2 μM.</p>Formula:C18H14BrNO4S2Purity:99.756%Color and Shape:SolidMolecular weight:452.34Terrein
CAS:<p>Terrain (NSC 291308), a fungal metabolite, reduces age-related inflammation via Nrf2/ERK1/2/HO-1 and inhibits IL-6 in human fibroblasts.</p>Formula:C8H10O3Color and Shape:SolidMolecular weight:154.16RET ligand-3
<p>RETligand-3 is the ligand for PROTAC QZ2135, which targets RET.</p>Formula:C38H42N10O3Color and Shape:SolidMolecular weight:686.81Anticancer agent 39
CAS:<p>Compound B12, a JOA derivative, collapses MMP to induce apoptosis, inhibits cloning/migration, and has an IC50 of 0.39 μM against HGC-27 cells.</p>Formula:C50H65N5O10Color and Shape:SolidMolecular weight:896.08Shepherdin (79-87)
CAS:<p>Shepherdin 79-87: Amino acid fragment 79-87 of Hsp90/Survivin antagonist with anticancer properties.</p>Formula:C41H64N12O12SPurity:98%Color and Shape:SolidMolecular weight:949.09PROTAC RIPK degrader-6
CAS:<p>PROTAC RIPK degrader-6 (example 1) is a PROTAC designed for the targeted degradation of RIP Kinase, featuring a RIP2 kinase inhibitor connected through a linker</p>Formula:C43H48N6O11S2Color and Shape:SolidMolecular weight:889.01
