Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(17 products)
- Survivin(14 products)
- TNF(91 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6170 products of "Apoptosis"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
p53-HDM2-IN-1
p53-HDM2-IN-1 is a potent inhibitor of the p53-HDM2 protein-protein interaction, demonstrating an inhibitory concentration (IC 50) of 0.103 μM.Formula:C35H38F6N4O7SColor and Shape:SolidMolecular weight:772.75Onfekafusp alfa
CAS:Onfekafusp alfa (L19TNF), a trimeric fusion of L19 scFv and human TNF, targets malignant glioma.Color and Shape:LiquidAnti-Mouse TNF α Antibody (TN3-19.12)
Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.Purity:95%Color and Shape:Odour LiquidMolecular weight:150 kDaSpexin
CAS:Potent GAL2/GAL3 agonist (EC50 = 45.7, 112.2 nM), inactive at GAL1. Reduces appetite, fatty acid uptake in adipocytes, and LH in goldfish; anxiolytic in vivo.Formula:C74H114N20O19SPurity:98%Color and Shape:SolidMolecular weight:1619.9Cofetuzumab
CAS:Cofetuzumab (PF-06523435) is a antibody targeting protein tyrosine kinase 7 (PTK7), which can be used to synthesize ADC compounds like cofetuzumab pelidotin.Purity:>95%Color and Shape:LiquidMolecular weight:146.7 kDaPROTAC GPX4 degrader-2
PROTACGPX4 degrader-2 (compound 18a) is a proteolysis-targeting chimera (PROTAC) that targets the degradation of glutathione peroxidase 4 (GPX4), with a DC50, 48h value of 1.68 μM. It induces the accumulation of lipid peroxides and mitochondrial depolarization, subsequently triggering ferroptosis. Additionally, PROTACGPX4 degrader-2 exhibits antiproliferative activity.Formula:C50H61ClN8O9Molecular weight:952.425Antitumor photosensitizer-7
Antitumor photosensitizer-7 (compound 15), a photosensitizer possessing anti-cancer properties, demonstrates substantial cytotoxic effects on the G361 melanoma cell line when exposed to 414 nm blue light irradiation.Formula:C23H20N2O3Color and Shape:SolidMolecular weight:372.42Atorolimumab
CAS:Atorolimumab (P3x22914G4), a monoclonal antibody, is employed in immunotherapies that target the programmed death-1 (PD-1) receptor [1].Color and Shape:LiquidMDM2/4-p53-IN-3
MDM2/4-p53-IN-3 inhibits MDM2/4-p53 PPIs (IC50: 18.5nM MDM2, 14.8nM MDM4), used in cancer research.Formula:C25H24Cl2FN3O3Color and Shape:SolidMolecular weight:504.38Urelumab
CAS:"Urelumab (BMS-66513), a humanized IgG4 mAb CD137 agonist, boosts T-cell/NK cell-mediated cytotoxicity and anti-tumor activity."Purity:97.70%Color and Shape:LiquidMolecular weight:145.90 kDaRanevetmab
CAS:Ranevetmab (NV-01), a caninized anti-NGF mAb, relieves pain in DJD research.Color and Shape:LiquidDimethachlor
CAS:Dimethachlor is a pesticide and herbicide used in wetland areas.Formula:C13H18ClNO2Color and Shape:SolidMolecular weight:255.74Pegsunercept
CAS:Pegsunercept (PEG sTNF-RI), a pegylated monoclonal antibody, selectively binds to TNFA, incorporating a polyethylene glycol (pegol) moiety [1].Color and Shape:LiquidHKB99
CAS:HKB99 suppresses NSCLC growth, metastasis, and overcomes erlotinib resistance.Formula:C23H18N2O6SPurity:97.35% - 97.35%Color and Shape:SolidMolecular weight:450.465α-dihydro Levonorgestrel
CAS:5α-dihydro Levonorgestrel is a metabolite of the synthetic progestin levonorgestrel .Formula:C21H30O2Color and Shape:SolidMolecular weight:314.469Tralokinumab
CAS:Tralokinumab: human IgG4 monoclonal antibody, blocks IL-13, may treat atopic dermatitis.Purity:SDS-PAGE:95% SEC-HPLC:99.99%Color and Shape:LiquidMolecular weight:144.14 kDaMS105
CAS:MS105 is an orally active, selective protein tyrosine kinase 6 (PTK6) PROTAC degrader. It recruits the VHL E3 ligase through a VHL ligand fragment, facilitating ubiquitination and proteasomal degradation of PTK6, thereby inhibiting the proliferation and migration of breast cancer cells and inducing apoptosis (apoptosis). MS105 is a promising compound for breast cancer research.Formula:C56H70FN13O6SColor and Shape:SolidMolecular weight:1072.30Haemanthamine hydrochloride
Haemanthamine hydrochloride, an alkaloid from Amaryllidaceae, has anticancer, antioxidant, antiviral, antimalarial, and anticonvulsant properties.Formula:C17H20ClNO4Color and Shape:SolidMolecular weight:337.8Oxatomide
CAS:Oxatomide: Dual H1/P2X7 antagonist, antihistamine, anti-allergic, treats immune diseases, IC50: 0.95 μM (P2X7), 0.43 μM (5-HT).Formula:C27H30N4OPurity:99.28% - 99.72%Color and Shape:White PowderMolecular weight:426.55Ref: TM-T19839
1mg35.00€5mg75.00€10mg114.00€25mg222.00€50mg356.00€100mg557.00€500mg1,153.00€1mL*10mM (DMSO)84.00€N-Acetylpsychosine
CAS:N-Acetylpsychosine, also known as α-galactosylated C2-ceramide (d18:1/2:0), exhibits immunostimulatory properties.
Formula:C26H49NO8Color and Shape:SolidMolecular weight:503.67
