Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(17 products)
- Survivin(14 products)
- TNF(91 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6170 products of "Apoptosis"
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Thalidomide-5-PEG2-Cl
CAS:Thalidomide-5-PEG2-Cl is a cereblon ligand that recruits CRBN protein and forms PROTACs through linker conjugation.Formula:C17H17ClN2O6Color and Shape:SolidMolecular weight:380.78FPR1 antagonist 2
Compound 25b, an FPR1 antagonist, exhibits potent inhibition of the formyl peptide receptor 1 with an IC50 of 70 nM.Formula:C25H25F3O5Color and Shape:SolidMolecular weight:462.46Stem bromelain
CAS:Stem bromelain: cysteine protease from pineapple stem with fibrinolytic, anti-inflammatory, antitumoral properties.Color and Shape:SolidS-Adenosyl-L-methionine
CAS:S-Adenosyl-L-methionine (Ademetionine) is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.Formula:C15H22N6O5SPurity:99.08%Color and Shape:SolidMolecular weight:398.44HG-7-85-01
CAS:HG-7-85-01 is a novel ATP-competitive and type II tyrosine kinase inhibitor targeting both wild-type and watchman mutant BCR-ABL, PDGFRα, Kit, and Src kinases.Formula:C31H31F3N6O2SPurity:98.08%Color and Shape:SolidMolecular weight:608.68Xerophilusin B
CAS:Xerophilusin B from Isodon xerophilus halts ESCC cell growth, causes G2/M arrest, and induces apoptosis.Formula:C20H26O5Color and Shape:SolidMolecular weight:346.42Top1-IN-2
Top1-IN-2 (Compound 1a) is an inhibitor of topoisomerase 1 (Top1). It suppresses the growth of P-gp drug-resistant tumor cells and induces apoptosis.Color and Shape:Odour Solidp53 (17-26)
CAS:Peptide is p53's amino acids 17-26, contacts Mdm-2 binding domain, also called p53N.Formula:C60H90N12O17Purity:98%Color and Shape:SolidMolecular weight:1251.43RD-23
CAS:RD-23 is an orally active and selective RET PROTAC degrader. It facilitates the ubiquitination and degradation of the RETG810C mutant with a DC50 value of 11.7 nM. Additionally, RD-23 inhibits the activation of downstream Shc signaling and induces apoptosis (Apoptosis). It is useful for studying RET-related cancers.Formula:C52H56N12O4Color and Shape:SolidMolecular weight:913.079Lacto-N-fucopentaose I
CAS:Lacto-N-fucopentaose I is a milk oligosaccharide.Formula:C32H55NO25Color and Shape:SolidMolecular weight:853.774β-Glucuronide-dPBD-PEG5-NH2 TFA
CAS:β-Glucuronide-dPBD-PEG5-NH2 TFA is a β-glucuronide-linked pyrrolobenzodiazepine dimer employed in the synthesis of the antibody-drug conjugate (ADC) cIRCR201-Formula:C80H102F3N7O37Color and Shape:SolidMolecular weight:1810.69Thalidomide-NH-C8-NH2
CAS:Thalidomide-NH-C8-NH2 is a synthetic E3 ligase ligand-linker for PROTAC, combining cereblon ligand and a specific linker.Formula:C21H28N4O4Color and Shape:SolidMolecular weight:400.479FeTPPS
CAS:FeTPPS, a decomposition catalyst for 5,10,15,20-tetrakis(4-sulfonatophenyl) porphyrin iron(III) chloride peroxynitrite, neuroprotective.Formula:C44H28ClFeN4O12S4Color and Shape:SolidMolecular weight:1024.27Tubulysin B
CAS:Tubulysin B: a potent, cytotoxic microtubule-disrupting peptide from Archangium geophyra and Angiococcus disciformis.Formula:C42H63N5O10SPurity:98%Color and Shape:SolidMolecular weight:830.04PZ703b
CAS:PZ703b is a novel BCL-XL PROTAC degrader with enhanced BCL-2 inhibition.Formula:C80H102ClF3N10O11S4Color and Shape:SolidMolecular weight:1600.44BM-1074
CAS:BM-1074 is a potent and highly efficacious inhibitor of Bcl-2/Bcl-xL with Ki value of < 1nM [1].Formula:C50H57ClN8O7S3Color and Shape:SolidMolecular weight:1013.69Kurzipene D
CAS:Kurzipene D: anticancer, induces apoptosis, halts HepG2 at S phase, anti-tumor in zebrafish, inhibits tumor growth and spread.Formula:C26H36O8Color and Shape:SolidMolecular weight:476.56Anticancer agent 52
CAS:Anticancer agent 52 exhibits potent cytotoxicity, induces apoptosis, and has potential in bladder cancer research.Formula:C50H43Br2N2PColor and Shape:SolidMolecular weight:862.67CSF1R-IN-26
CAS:CSF1R-IN-26 (Compound III-1) is an inhibitor of CSF-1R with an IC50 of 20.07 nM. It promotes the polarization of M2 macrophages to M1 macrophages, inducing apoptosis in MC-38 cancer cells. CSF1R-IN-26 inhibits the activation of the AKT/ERK/STAT3 signaling pathways, remodels the tumor immune microenvironment, and exhibits antitumor activity in mouse models. In SD rats, CSF1R-IN-26 demonstrates favorable pharmacokinetic properties, with a half-life of 1.86 hours and an oral bioavailability of 79.22%.Formula:C20H22ClN5O3Color and Shape:SoildMolecular weight:415.877-epi-Isogarcinol
CAS:7-epi-Isogarcinol, a PPAP, hinders STAT3 to induce apoptosis and curbs cell migration with moderate antiproliferative effects.Formula:C38H50O6Color and Shape:SolidMolecular weight:602.8
