Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(17 products)
- Survivin(14 products)
- TNF(91 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6170 products of "Apoptosis"
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β-Amyloid (1-40) (rat)
CAS:Rat form of the beta-Amyloid (1-40) peptideFormula:C190H291N51O57SPurity:98%Color and Shape:SolidMolecular weight:4233.76LY3415244
LY3415244 is a human bispecific antibody (bsAb) that targets B7-H1/PD-L1/CD274 and TIM-3/HAVCR2/CD366. This compound is applicable in the study of advanced solid tumors.Color and Shape:Odour LiquidAscochlorin
CAS:Ascochlorin, an isoprenoid antibiotic, inhibits STAT3 to combat tumors, induces apoptosis, and reduces inflammation.Formula:C23H29ClO4Purity:98%Color and Shape:SolidMolecular weight:404.93PROTAC RIPK degrader-2
CAS:PROTAC RIPK degrader-2 is a nonpeptidic PROTAC ,and potently targets serine-threonine kinase RIPK2 and has highly selective for RIPK2 degradation.Formula:C52H65N7O11S3Purity:98%Color and Shape:SolidMolecular weight:1060.31PI3Kδ-IN-16
CAS:PI3Kδ-IN-16 is a selective and potent PI3Kδ inhibitor with anticancer and antiproliferative activity, induces cell cycle arrest and apoptosis.Formula:C22H26N6O2Purity:99.68%Color and Shape:SoildMolecular weight:406.48Psalmotoxin 1
CAS:Psalmotoxin 1 is a potent and selective acid-sensing ion channel 1a (ASIC1a) blocker.Formula:C200H312N62O57S6Purity:98%Color and Shape:SolidMolecular weight:4689.41SP3N hydrochloride
SP3N hydrochloride is a specific degrader of the prolyl isomerase (FKBP12). Its alkylamine moiety is metabolized into an active aldehyde (SP3CHO), which recruits the SCFFBXO22 ligase for the degradation of FKBP12. SP3N hydrochloride is applicable in cancer research.Color and Shape:Odour SolidSuramin
CAS:Suramin is an RdRp and PTPase inhibitor with anti-parasitic, anti-tumor, and anti-angiogenic activities, inhibiting sirtuins and DNA topoisomerase II.Formula:C51H40N6O23S6Purity:99.80%Color and Shape:SolidMolecular weight:1297.28PZ703b hydrochloride
PZ703b hydrochloride, a Bcl-xl PROTAC, triggers apoptosis and halts cancer growth; used in bladder cancer studies.Formula:C80H103Cl2F3N10O11S4Color and Shape:SolidMolecular weight:1636.9Thalidomide-O-amido-C8-NH2 hydrochloride
Thalidomide-O-amido-C8-NH2 hydrochloride, a synthetic cereblon ligand-linker for PROTAC synthesis.Formula:C23H31ClN4O6Purity:98%Color and Shape:SolidMolecular weight:494.974-hydroperoxy cyclophosphamide
CAS:4-hydroperoxy cyclophosphamide (4-OOH-CY) induces hepatotoxicity. It increases ghrelin levels and enhances inflammatory factors and oxidative markers.Formula:C7H15Cl2N2O4PPurity:98%Color and Shape:SolidMolecular weight:293.09SDH-IN-26
SDH-IN-26 (Compound C3) is a succinate dehydrogenase (SDH) inhibitor with significant inhibitory activity against various plant pathogenic fungi, including solanrhizoctonia and Botrytis cinerea. It exhibits an EC50 value of 0.270 μg/mL against solanrhizoctonia. SDH-IN-26 compromises fungal cell membrane integrity, increases membrane permeability, disrupts cell structure, reduces mitochondrial count, and affects normal hyphal growth. It also decreases mitochondrial membrane potential, inducing apoptosis. SDH-IN-26 holds potential for studying plant diseases caused by fungi.Color and Shape:Odour SolidCPTH2 (hydrochloride) (357649-93-5 free base)
CAS:CPTH2 is an inhibitor of the HAT activity of Gcn5.Formula:C14H15Cl2N3SPurity:98%Color and Shape:SolidMolecular weight:328.26ZZM-1220
ZZM-1220, a covalent inhibitor of histone lysine methyltransferase G9a/GLP, exhibits IC50 values of 458 nM for G9a and 924 nM for GLP.Formula:C25H29N5O3Purity:98%Color and Shape:SolidMolecular weight:447.53Ac-VDVAD-CHO TFA
Ac-VDVAD-CHO (TFA) is a caspase-2/3 inhibitor with IC50 values of 46 nM and 15 nM, respectively.Color and Shape:Odour SolidPZ703b
CAS:PZ703b is a novel BCL-XL PROTAC degrader with enhanced BCL-2 inhibition.Formula:C80H102ClF3N10O11S4Color and Shape:SolidMolecular weight:1600.44PL120131
PL120131 is a PD-1/PD-L1 inhibitory peptide that disrupts the interaction between PD-1 and PD-L1 by binding to PD-1. This compound can inhibit the apoptosis signaling pathway mediated by PD-1, thereby preventing apoptosis (apoptosis) in Jurkat cells and primary lymphocytes. Additionally, PL120131 supports cytotoxic T lymphocytes (CTL) in exhibiting antitumor activity.Formula:C62H105N19O18Color and Shape:SolidMolecular weight:1404.61RIPK3-IN-3
RIPK3-IN-3 (compound 20) is a selective RIPK3 inhibitor that demonstrates potent activity with an IC50 value of 10 nM.Formula:C16H11N5SColor and Shape:SolidMolecular weight:305.36Fuscin
CAS:Fuscin, a quinonoid from O. fuscum, inhibits ADP/ATP translocase, depletes glutathione, disrupts NADH oxidation, and blocks MIP-1α/CCR5 binding (IC50: 21µM).Formula:C15H16O5Color and Shape:SolidMolecular weight:276.288Shepherdin (79-87)
CAS:Shepherdin 79-87: Amino acid fragment 79-87 of Hsp90/Survivin antagonist with anticancer properties.Formula:C41H64N12O12SPurity:98%Color and Shape:SolidMolecular weight:949.09
