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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 5592 products of "Apoptosis"

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  • EGFR-PK/JNK-2-IN-1


    <p>EGFR-PK/JNK-2-IN-1 (Compound 6c) is a dual inhibitor of EGFR-PK and JNK-2, with IC50 values of 2.7 and 3.0 μM, respectively. It can induce apoptosis and cause cell cycle arrest at various stages. This compound is applicable in cancer research.</p>
    Formula:C22H17ClN4O3S
    Molecular weight:452.07099
  • Anticancer agent 178


    <p>Anticanceragent 178 (compound C2) is a potent anticancer compound. It effectively inhibits the proliferation and metabolic activity of MDA-MB 231 cells, with IC50 values of 1.1 and 4.2 μM, respectively. Additionally, Anticanceragent 178 induces ferroptosis and necroptosis in cells.</p>
    Formula:C32H30ClFeN2O6
    Molecular weight:629.11418
  • LC-1-40


    <p>LC-1-40 is a PROTAC that selectively degrades NUDT1 (DC50=0.97 nM). In mouse models, LC-1-40 selectively inhibits tumor growth induced by MYCN and induces nucleotide damage and apoptosis (cell death) in MYCN-associated tumors. It is applicable for cancer research.</p>
    Formula:C49H48N8O6
    Molecular weight:844.36968
  • Pim-1 kinase inhibitor 4


    <p>Pim-1 kinase inhibitor 4 is a potent Pim-1 kinase inhibitor with an IC50 value of 17.01 nM.Pim-1 kinase inhibitor 4 also possesses antioxidant activity and</p>
    Formula:C19H12ClN3O
    Purity:97.72%
    Color and Shape:Solid
    Molecular weight:333.77
  • MALT1-IN-13


    <p>MALT1-IN-13 (compound 10m) is an inhibitor of the mucosa-associated lymphoid tissue lymphoma translocation protein (MALT1), forming a covalent and irreversible bond with the MALT1 protease, thereby inhibiting its activity with an IC50 of 1.7 μM. It suppresses the proliferation of ABC-DLBCL and induces apoptosis in ABC-DLBCL HBL1 cells. Additionally, MALT1-IN-13 regulates the mTOR and PI3K-Akt pathways.</p>
    Formula:C20H15BrClN3O3S2
    Molecular weight:522.94267
  • Lw13


    <p>Lw13 is a PROTAC targeting Hsp90, exhibiting maximal degradation efficacy at a concentration of 0.05 μM in Siha cells. Lw13 induces apoptosis and demonstrates potent antitumor activity both in vitro and in vivo.</p>
    Formula:C46H55F3N8O8
    Molecular weight:904.4095
  • ZC0109


    <p>ZC0109 inhibits IDO1 (50 nM) &amp; TrxR1 (3.0 μM), induces ROS, arrests G1/S phase, causing cancer cell apoptosis.</p>
    Formula:C22H20BrFN8O4S
    Color and Shape:Solid
    Molecular weight:591.41
  • Prolgolimab

    CAS:
    <p>Prolgolimab (BCD-100) is an anti-PD-1 antibody used in melanoma research.</p>
    Purity:>95%
    Color and Shape:Liquid
  • HPOB

    CAS:
    <p>HPOB is an effective and specific HDAC6 inhibitor (IC50: 56 nM), &gt;30-fold selectivity over other HDACs.</p>
    Formula:C17H18N2O4
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:314.34
  • BOC-D-FMK

    CAS:
    <p>Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 μM).</p>
    Formula:C11H18FNO5
    Purity:97.02%
    Color and Shape:Solid
    Molecular weight:263.26
  • Spexin

    CAS:
    <p>Potent GAL2/GAL3 agonist (EC50 = 45.7, 112.2 nM), inactive at GAL1. Reduces appetite, fatty acid uptake in adipocytes, and LH in goldfish; anxiolytic in vivo.</p>
    Formula:C74H114N20O19S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1619.9
  • Hellebrin

    CAS:
    <p>Cytotoxic and antiproliferative effects of Hellebrin on breast and lung cancer cells.</p>
    Formula:C36H52O15
    Color and Shape:Solid
    Molecular weight:724.79
  • Syringolin A

    CAS:
    <p>Syringolin A is a useful organic compound for research related to life sciences. The catalog number is T125354 and the CAS number is 212115-96-3.</p>
    Formula:C24H39N5O6
    Color and Shape:Solid
    Molecular weight:493.605
  • BLU-222

    CAS:
    <p>BLU-222 is a potent, selective and orally active CDK2 inhibitor. BLU-222 shows robust antitumor activity.</p>
    Formula:C15H17F2N7O2
    Purity:99.17% - 99.92%
    Color and Shape:Soild
    Molecular weight:365.34
  • Amorfrutin A

    CAS:
    <p>Amorfrutin A is a useful organic compound for research related to life sciences. The catalog number is T124190 and the CAS number is 80489-90-3.</p>
    Formula:C21H24O4
    Color and Shape:Solid
    Molecular weight:340.419
  • (E/Z)-LAQ824

    CAS:
    <p>(E/Z)-LAQ824 is an inhibitor of histone deacetylase.</p>
    Formula:C22H25N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:379.46
  • S-Adenosyl-L-methionine iodide

    CAS:
    <p>S-(5'-Adenosyl)-L-methionine iodide, also known as S-Adenosyl-L-methionine iodide, is a vital methyl donor present in all living organisms [1].</p>
    Formula:C15H23IN6O5S
    Color and Shape:Solid
    Molecular weight:526.35
  • Phosphocreatine dipotassium

    CAS:
    <p>Phosphocreatine dipotassium, primarily found in the skeletal muscles of vertebrates and one of organic compounds known as alpha amino acids and derivatives.</p>
    Formula:C4H8K2N3O5P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:287.29
  • Sodium propionate

    CAS:
    <p>Sodium propionate (Propionic acid sodium salt) has potential anti-inflammatory and anti-apoptotic activities, inhibiting certain signaling pathways.</p>
    Formula:C3H5NaO2
    Color and Shape:Soild
    Molecular weight:96.06
  • ChoKα inhibitor-4


    <p>ChoKα Inhibitor-4 is a bioisosteric agent that effectively inhibits human choline kinase α1 (HChoK α1) with an IC50 of 0.66 μM.</p>
    Color and Shape:Odour Solid