Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(116 products)
- PDK(9 products)
- PERK(24 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(65 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6114 products of "Apoptosis"
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MK-4688
CAS:MK-4688 is an efficient inhibitor of the HDM2-p53 protein-protein interaction.Formula:C28H32ClN7O3Color and Shape:SolidMolecular weight:550.06CWI1-2 HCL
CAS:CWI1-2 HCL: Potent IGF2BP2 inhibitor, induces apoptosis/differentiation, targets leukemia therapy.Formula:C22H18Cl4N6O3Purity:98.09%Color and Shape:SolidMolecular weight:556.23Ref: TM-T67930L
1mg49.00€5mg92.00€10mg145.00€25mg281.00€50mg409.00€100mg580.00€200mg798.00€1mL*10mM (DMSO)116.00€Δ8-Tetrahydrocannabinoquinone
CAS:Δ8-Tetrahydrocannabinoquinone (HU-336) is a potent anti-angiogenic agent that inhibits angiogenesis by directly inducing apoptosis in vascular endothelial cells. It achieves this without altering the expression of pro-angiogenic and anti-angiogenic cytokines and receptors. Δ8-Tetrahydrocannabinoquinone also shows significant effectiveness against tumor xenografts in nude mice.Formula:C21H28O3Color and Shape:SolidMolecular weight:328.45Caspase-3/7 activator 1
Caspase-3/7 activator 1 is an effective activator of Caspase-3/7 that exhibits tumor-selective, antiproliferative activity and high apoptosis (Apoptosis) induction capability.Formula:C26H28N2O5Molecular weight:448.19982Antitumor agent-36
Antitumor agent-36: potent anti-cancer; causes DNA damage, triggers apoptosis, enhances immune response by upregulating T cells.Formula:C32H30Cl2N2O6PtColor and Shape:SolidMolecular weight:804.58PMT-O9-1A
PMT-O9-1A is an effective PD-L1 degrader that reduces PD-L1 protein expression and exhibits cytotoxic properties. Additionally, PMT-O9-1A possesses anticancer activity.Formula:C22H25ClN2O4Color and Shape:SolidMolecular weight:416.90IMMH 010 maleate
CAS:IMMH 010 maleate (YPD-30 maleate) is a programmed cell death ligand 1 inhibitor used in the study of neurological disorders and advanced malignant solid tumors.Formula:C36H36BrClN2O9Color and Shape:SoildMolecular weight:756.042-Methylbiphenyl-oxadiazole-NH-Ph-NH-PEG3-C2-NH-Boc
2-Methylbiphenyl-oxadiazole-NH-Ph-NH-PEG3-C2-NH-Boc is the PD-L1 ligand-linker polymer of AUTACPD-L1degrader-3. It can be utilized in the synthesis of AUTAC.Formula:C35H45N5O6Color and Shape:SolidMolecular weight:631.76Satratoxin H
CAS:Satratoxin H is an air- and food-borne mycotoxin, which has been implicated in human health damage.Formula:C29H36O9Color and Shape:SolidMolecular weight:528.598Salinomycin sodium salt
CAS:Salinomycin sodium salt (Sodium salinomycin), an antibiotic potassium ionophore, is an effective inhibitor of Wnt/β-catenin signaling.Formula:C42H69NaO11Purity:98.76% - 99.11%Color and Shape:White Or Light Yellow Crystalline Powder With Special SmelMolecular weight:772.98Barakol
CAS:Barakol, a primary compound found in Cassia siamea, inhibits MMP-3 activity and enhances the anti-metastatic effects of doxorubicin. Additionally, Barakol induces apoptosis (Apoptosis), generates reactive oxygen species, increases the Bax/Bcl-2 expression ratio, and activates caspase-9. This compound also exhibits laxative, anti-anxiety, central nervous system depressant, antioxidant, and anticancer properties.Formula:C13H12O4Color and Shape:SolidMolecular weight:232.23Antitumor agent-116
Antitumor Agent-116 (Compound 6C) is an anti-tumor agent that exhibits anti-proliferative properties and induces apoptosis.Formula:C31H23BrN4O4SPurity:98%Color and Shape:SolidMolecular weight:627.51Ganoderic acid T1
Ganoderic acid T1, a derivative of Ganoderic acid T, triggers cancer cell apoptosis by boosting ROS and activating caspases.Formula:C34H50O7Color and Shape:SolidMolecular weight:570.76HSP90-IN-33
HSP90-IN-33 (compound 24e) is an effective Hsp90 inhibitor, demonstrating dissociation constants (Kd) of ≥200 µM for Hsp90α and 7.3 µM for Hsp90β. This compound induces cellular apoptosis (apoptosis) and arrests the cell cycle at the G0/G1 phase. Additionally, HSP90-IN-33 reduces the protein expression of ERα, CDK4, and Akt.Formula:C21H25Cl2N5O2Color and Shape:SolidMolecular weight:450.36TOPOI/PARP-1-IN-2
TOPOI/PARP-1-IN-2 (compound 6c) serves as a dual inhibitor targeting both PARP-1 and topoisomerase 1 (TOPO-1), with IC50 values of 32.2 nM and 46.2 nM, respectively. This compound exhibits greater selectivity for PARP-1 over PARP-2. Additionally, TOPOI/PARP-1-IN-2 disrupts the S phase of the cell cycle and induces apoptosis in the NCI-60 cancer cell lines.Formula:C16H11ClN4O2SColor and Shape:SolidMolecular weight:358.80Bfl-1-IN-5
Bfl-1-IN-5 (Compound (R,R,S)-26) is a selective inhibitor of Bfl-1, demonstrating an IC50 of 0.022 μM. This compound enhances the activity of caspase-3/7, with an EC50 of 0.37 μM, and also inhibits the viability of SU-DHL-1 cells, showing an EC50 of 1.3 μM.Formula:C24H24F3N3O2Color and Shape:SolidMolecular weight:443.46LBM22
LBM22, a CLK2 inhibitor, exhibits an IC50 value of 3.9 nM. It possesses anti-proliferative properties by inhibiting the phosphorylation of SR proteins. Additionally, LBM22 downregulates the expression of Wnt-related proteins and anti-apoptotic proteins, making it applicable in the study of non-small cell lung cancer.Formula:C28H22F2N6O2Color and Shape:SolidMolecular weight:512.51Antibiotic DC 81
CAS:DC 81: Streptomyces-derived antitumor antibiotic, potent nucleic acid synthesis inhibitor, binds DNA sequences, forms covalent adducts.Formula:C13H14N2O3Color and Shape:SolidMolecular weight:246.262,4-D sodium salt
CAS:Sodium 2,4-dichlorophenoxyacetate: selective herbicide, controls broadleaf weeds by disrupting growth and protein/DNA synthesis.Formula:C8H5Cl2NaO3Color and Shape:SolidMolecular weight:243.02CDK2-IN-32
CDK2-IN-32 (Compound 5g) is a selective CDK2 inhibitor with an IC50 of 0.21 μM. It exhibits cytotoxicity towards Vero cells with an IC50 of 28.52 μM.Formula:C18H13Cl2N5O2Color and Shape:SolidMolecular weight:402.23
