Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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PERK-IN-6
CAS:<p>PERK-IN-6 is a novel and highly potent PERK inhibitor (IC50:2.5 nM).</p>Formula:C23H22N6OPurity:99.62% - 99.92%Color and Shape:SolidMolecular weight:398.46Kurzipene D
CAS:<p>Kurzipene D: anticancer, induces apoptosis, halts HepG2 at S phase, anti-tumor in zebrafish, inhibits tumor growth and spread.</p>Formula:C26H36O8Color and Shape:SolidMolecular weight:476.56BMH-7 HCl
<p>BMH-7 HCl is a p53 activator, showing anti-cancer activity by activating the p53 pathway.</p>Formula:C20H22ClN5OPurity:99.62%Color and Shape:SolidMolecular weight:383.88Taccalonolide E
CAS:<p>Taccalonolide E is a microtubule stabilizer and induces cancer cell apoptosis .</p>Formula:C34H44O12Color and Shape:SolidMolecular weight:644.71Ro 48-8071
CAS:<p>Oxidosqualene cyclase inhibitor</p>Formula:C23H27BrFNO2Purity:98%Color and Shape:SolidMolecular weight:448.37Antiproliferative agent-59
<p>Antiproliferative agent-59 (Compound 14u) acts as an inhibitor of tubulin polymerization. Demonstrating anticancer activity in Huh7, SGC-7901, and MCF-7 cell lines, this compound achieves IC50 values of 0.03, 0.18, and 0.13 μM, respectively. Additionally, it arrests the cell cycle at the G2/M phase and induces apoptosis in Huh7 cells. In a xenograft mouse model utilizing Huh7 cells, Antiproliferative agent-59 exhibits antitumor effects against hepatocellular carcinoma without significant toxicity.</p>Formula:C26H22N2O3Color and Shape:SolidMolecular weight:410.46Sasanlimab
CAS:<p>Sasanlimab (PF-06801591), a humanized IgG4-κ antibody, selectively targets PD-1 and is primarily produced in Chinese Hamster Ovary (CHO) cells [1].</p>Purity:98%Color and Shape:LiquidThalidomide-NH-PEG3-COOH
CAS:<p>Thalidomide-NH-PEG3-COOH is a cereblon-based E3 ligase ligand-linker for PROTAC synthesis.</p>Formula:C22H27N3O9Color and Shape:SolidMolecular weight:477.47LSD1-IN-36
<p>LSD1-IN-36, an effective LSD1 inhibitor with an IC50 value of 0.8 nM, induces cell apoptosis and arrests the cell cycle. This compound also exhibits antitumor activity.</p>Formula:C22H25N3O6SColor and Shape:SolidMolecular weight:459.52BCL-XL-IN-1
<p>BCL-XL-IN-1 (Compound 11) is a selective inhibitor of BCL-XL, exhibiting a Ki of less than 0.01 nM against BCL-XLTR-FERT. It is primarily used in cancer research.</p>Formula:C46H55N7O6SColor and Shape:SolidMolecular weight:834.04AKT-IN-18
<p>AKT-IN-18, an Akt inhibitor, demonstrates an IC50 value of 69.45 μM in A549 cells, effectively impeding Akt activity.</p>Formula:C19H14ClN5O2SPurity:98%Color and Shape:SolidMolecular weight:411.862,4,6-trichloroanisole
CAS:<p>2,4,6-trichloroanisole inhibits the cell viability of CHO and C32 cell lines and apoptosis, antibacterial activity against Plasmodium falciparum.</p>Formula:C7H5Cl3OPurity:99.93%Color and Shape:SolidMolecular weight:211.47Antiproliferative agent-23
<p>Antiproliferative agent-23: destabilizes microtubules, induces apoptosis in cancer cells via mitochondrial path, and triggers ER stress.</p>Formula:C23H28Cl3N3O6PtColor and Shape:SolidMolecular weight:743.93HDAC-IN-84
<p>HDAC-IN-84 (compound 4a) is a potent HDAC inhibitor with IC50 values of 0.0045, 0.015, 0.013, 0.038, 5.8, and 26 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC11, respectively. It effectively inhibits the proliferation of leukemia cells without causing toxicity.</p>Formula:C17H21N3O5SColor and Shape:SolidMolecular weight:379.431Thalidomide-O-amido-C3-NH2
CAS:<p>Thalidomide-derived cereblon ligand linked to a PROTAC technology linker, Thalidomide-O-amido-C3-NH2, is a synthetic E3 ligase ligand-linker.</p>Formula:C18H20N4O6Color and Shape:SolidMolecular weight:388.37Thalidomide-O-amido-C4-N3
CAS:<p>Thalidomide-O-amido-C4-N3 (Cereblon Ligand-Linker Conjugates 4) is an E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and</p>Formula:C19H20N6O6Purity:97.01%Color and Shape:SolidMolecular weight:428.4Golimumab
CAS:<p>Golimumab (CNTO-148), an anti-TNFα IgG1κ monoclonal antibody with anti-inflammatory and anti-cancer activity, can be used to prevent inflammation and cartilage.</p>Color and Shape:LiquidMolecular weight:146.93 kDaEtanercept
CAS:<p>Etanercept is a fusion protein consisting of the soluble portion of the p75-tumor necrosis factor receptor (TNFR) and the Fc fragment of human IgG1 and is commonly used to treat patients with rheumatoid arthritis.Cost-effective and quality-assured.</p>Purity:98%Color and Shape:LiquidIlicicolin A
CAS:<p>Ilicicolin A is a useful organic compound for research related to life sciences. The catalog number is T125289 and the CAS number is 22581-06-2.</p>Formula:C23H31ClO3Color and Shape:SolidMolecular weight:390.95PIM-1/CK2-IN-2
<p>PIM-1/CK2-IN-2 (compound 3aA) is an inhibitor of the PIM-1/CK2 enzymes. This compound can induce the mitochondrial apoptosis pathway in CCRF-CEM cells and is utilized in cancer research.</p>Formula:C15H8Br4N2OColor and Shape:SolidMolecular weight:551.85
