Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(19 products)
- Survivin(14 products)
- TNF(91 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6038 products of "Apoptosis"
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Thalidomide-O-C2-acid
CAS:Thalidomide-O-C2-acid: E3 ligase ligand-linker for PROTAC, with cereblon-derived Thalidomide component.Formula:C16H14N2O7Color and Shape:SolidMolecular weight:346.2916Thalidomide-NH-PEG3-COOH
CAS:Thalidomide-NH-PEG3-COOH is a cereblon-based E3 ligase ligand-linker for PROTAC synthesis.Formula:C22H27N3O9Color and Shape:SolidMolecular weight:477.47FGA139
<p>FGA139 is an inhibitor of cysteine proteases, specifically targeting cathepsin B and L with IC50 values of 4.98 μM and 3.14 μM, respectively. It reduces the production of NO in LPS-induced RAW264.7 cells and lowers TNFα levels in microglia, demonstrating antioxidant and anti-inflammatory properties. Additionally, FGA139 enhances the secretion of neuroprotective metabolites such as purines and linoleic acid in LPS-stimulated microglia. This compound is applicable in the study of neuroinflammatory diseases.</p>Formula:C48H58BF2N7O5Color and Shape:SolidMolecular weight:861.45605Ganoderic acid T1
<p>Ganoderic acid T1, a derivative of Ganoderic acid T, triggers cancer cell apoptosis by boosting ROS and activating caspases.</p>Formula:C34H50O7Color and Shape:SolidMolecular weight:570.76Lodapolimab
CAS:Lodapolimab (LY3300054) is an IgGλ anti- PD-1 monoclonal antibody [1] .Color and Shape:LiquidAntibiotic DC 81
CAS:DC 81: Streptomyces-derived antitumor antibiotic, potent nucleic acid synthesis inhibitor, binds DNA sequences, forms covalent adducts.Formula:C13H14N2O3Color and Shape:SolidMolecular weight:246.262,4-D sodium salt
CAS:Sodium 2,4-dichlorophenoxyacetate: selective herbicide, controls broadleaf weeds by disrupting growth and protein/DNA synthesis.Formula:C8H5Cl2NaO3Color and Shape:SolidMolecular weight:243.02Canfosfamide
CAS:Canfosfamide, a prodrug activated by GSTP1-1, induces apoptosis and inhibits DNA-PK, producing an alkylating agent for cancer research.Formula:C26H40Cl4N5O10PSColor and Shape:SolidMolecular weight:787.47Milademetan tosylate hydrate
CAS:Milademetan tosylate hydrate, an oral MDM2 inhibitor targeting AML and solid tumors, induces G1 arrest and apoptosis.Formula:C37H44Cl2FN5O8SColor and Shape:SolidMolecular weight:808.74Chloranthalactone B
CAS:Chloranthalactone B, a sesquiterpenoid from Sarcandra glabra, inhibits inflammation via AP-1 & p38 MAPK.Formula:C15H16O3Color and Shape:SolidMolecular weight:244.29RET-IN-4
CAS:RET-IN-4: Oral RET inhibitor, IC50 ~1 nM for variants. Selective over JAK2/FLT3. Potent anticancer use.Formula:C27H31FN10O2Color and Shape:SolidMolecular weight:546.611Thalidomide-NH-C6-NH-Boc
CAS:Thalidomide-based E3 ligase ligand for PROTAC degrader MI-389 synthesis, linked to cereblon and Boc.Formula:C24H32N4O6Color and Shape:SolidMolecular weight:472.542Thalidomide-NH-PEG2-COOH
CAS:Thalidomide-NH-PEG2-COOH: a synthesized E3 ligase ligand-linker with cereblon ligand and PROTAC linker.Formula:C20H23N3O8Color and Shape:SolidMolecular weight:433.417(Rac)-BIO8898
CAS:(Rac)-BIO8898 is a chemical compound that serves as an inhibitor of the co-stimulatory interaction between CD40 and CD154.Formula:C53H64N8O6Color and Shape:SolidMolecular weight:909.13Lenercept
CAS:<p>Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].</p>Color and Shape:LiquidAnticancer agent 104
Anticancer agent 104 has anticancer activity, and induces cancer cell apoptosis [1] .Formula:C34H47F3N2O2S2Color and Shape:SolidMolecular weight:636.87TAS-117
CAS:TAS-117, a PKB/Akt inhibitor, is used potentially for the treatment of solid tumors.Formula:C26H24N4O2Color and Shape:SolidMolecular weight:424.49Odoroside A
CAS:Odoroside A, from Nerium oleander leaves, induces cancer cell death via ROS/p53, causing apoptosis and cell cycle arrest.Formula:C30H46O7Color and Shape:SolidMolecular weight:518.68Xylopine
CAS:Xylopine: an aporphine alkaloid, cytotoxic to cancer cells, induces oxidative stress, G2/M arrest, and apoptosis.Formula:C18H17NO3Color and Shape:SolidMolecular weight:295.33Thalidomide-O-C4-COOH
CAS:Thalidomide-O-C4-COOH is a synthetic E3 ligase linker derived from Thalidomide for PROTAC tech.Formula:C18H18N2O7Color and Shape:SolidMolecular weight:374.3447
