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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 6063 products of "Apoptosis"

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  • RIPK1-IN-17
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    RIPK1-IN-17

    CAS:
    <p>RIPK1-IN-17 is a dual inhibitor of RIPK1 and RIPK3 inhibits necrosis by inhibiting phosphorylation of RIPK1, RIPK3 and MLKL,in a tnf-induced inflammation model.</p>
    Formula:C26H19F4N3O3S
    Purity:95.22%
    Color and Shape:Solid
    Molecular weight:529.51

    Ref: TM-T81268

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    Tubulin/AKT1-IN-1

    Tubulin/AKT1-IN-1 (Compound D1-1) serves as an inhibitor of both tubulin polymerization and AKT pathway activation, effectively suppressing proliferation and
    Formula:C38H34ClNO11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:716.13

    Ref: TM-T79214

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    FPR1 antagonist 1

    Compound 24a, an FPR1 antagonist, demonstrates potent inhibition of the formyl peptide receptor 1 (FPR1) with an IC50 value of 25 nM.
    Formula:C25H28O5
    Color and Shape:Solid
    Molecular weight:408.49

    Ref: TM-T79781

  • JC2-11
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    JC2-11

    CAS:
    <p>JC2-11 is an anti-inflammatory agent blocking NLRC 4, AIM 2, ROS production, caspase-1 activity, and reducing GSDMD, IL-1β, and LDH in vesicles.</p>
    Formula:C17H15FO4
    Purity:98.6%
    Color and Shape:Soild
    Molecular weight:302.3

    Ref: TM-T77579

  • GPX4-IN-6
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    GPX4-IN-6

    CAS:
    GPX4-IN-6 is a GPX4 inhibitor with antitumor activity.GPX4-IN-6 induces iron death and is used for the treatment and prevention of triple-negative breast cancer
    Formula:C18H17BrFNO5
    Purity:99.54%
    Color and Shape:Soild
    Molecular weight:426.23

    Ref: TM-T77759

  • Pipernonaline
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    Pipernonaline

    CAS:
    Pipernonaline is a useful organic compound for research related to life sciences. The catalog number is T124000 and the CAS number is 88660-10-0.
    Formula:C21H27NO3
    Color and Shape:Solid
    Molecular weight:341.451

    Ref: TM-T124000

  • eIF4E-IN-2
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    eIF4E-IN-2

    CAS:
    <p>eIF4E-IN-2 effectively inhibits eIF4e, crucial for research on diseases like cancer.</p>
    Formula:C37H33ClF2N8O4S2
    Color and Shape:Solid
    Molecular weight:791.29

    Ref: TM-T40214

  • DB2115 tertahydrochloride
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    DB2115 tertahydrochloride

    CAS:
    <p>DB2115 (tertahydrochloride) inhibits PU.1, key in leukemia; potential for cancer research.</p>
    Formula:C32H34Cl4N8O2
    Color and Shape:Solid
    Molecular weight:704.48

    Ref: TM-T38778

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    XZ338

    XZ338 is a highly selective degrader targeting BCL-XL without degrading BCL-2. It exhibits an IC50 value of 3.7 nM against MOLT-4 cells and possesses antiproliferative properties, making it useful for cancer research.
    Color and Shape:Odour Solid

    Ref: TM-T206912

  • anti-TNBC agent-1
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    anti-TNBC agent-1

    CAS:
    anti-TNBC agent-1 targets TNBC effectively, with IC50 of 0.20-0.27 μM, inducing apoptosis and G1 arrest in SUM-159 cells.
    Formula:C26H30O7
    Color and Shape:Solid
    Molecular weight:454.51

    Ref: TM-T39815

  • Calphostin C
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    Calphostin C

    CAS:
    Calphostin C is a protein kinase C inhibitor.
    Formula:C44H38O14
    Purity:98%
    Color and Shape:Red To Brown Powder
    Molecular weight:790.76

    Ref: TM-T22620

  • Ac-LEHD-AMC
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    Ac-LEHD-AMC

    CAS:
    Ac-LEHD-AMC, a fluorogenic caspase-9 substrate, releases fluorescent AMC upon cleavage, aiding caspase-9 activity measurement.
    Formula:C33H41N7O11
    Color and Shape:Solid
    Molecular weight:711.729

    Ref: TM-T36342

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    HQY1428

    HQY1428 is an orally active CDK12 inhibitor. It impedes DNA replication, causing cell cycle arrest at the G2/M phase in SKOV3 cells, and induces DNA double-strand breaks as well as apoptosis. In the SKOV3 xenograft mouse model, HQY1428 demonstrates antitumor activity. Additionally, when combined with the HER2 inhibitor Lapatinib in the NCI-N87 xenograft mouse model, HQY1428 produces a synergistic therapeutic effect.
    Formula:C25H28ClFN6O3S
    Color and Shape:Solid
    Molecular weight:546.16162

    Ref: TM-T207664

  • (E)-C-HDMAPP (ammonium salt)
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    (E)-C-HDMAPP (ammonium salt)

    CAS:
    <p>Alkyl phosphates like (E)-C-HDMAPP activate γδ-T cells, resist hydrolysis, and boost TNF-α synthesis and γδ-T cell count in vivo.</p>
    Formula:C6H23N3O7P2
    Color and Shape:Solid
    Molecular weight:311.21

    Ref: TM-T38039

  • 1,8-Cineole
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    1,8-Cineole

    CAS:
    Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.
    Formula:C10H18O
    Purity:97.44% - 97.44%
    Color and Shape:Solid
    Molecular weight:154.25

    Ref: TM-T1714

  • PD-1/PD-L1-IN-49
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    PD-1/PD-L1-IN-49

    <p>PD-1/PD-L1-IN-49 (compound 1c) is a potent inhibitor of PD-1/PD-L1 with an IC50 of 77 nM. This compound can activate Jurkat T cells and effectively block the PD-1/PD-L1 immune checkpoint.</p>
    Formula:C27H32N4O5
    Color and Shape:Solid
    Molecular weight:492.567

    Ref: TM-T206990

  • VK-28
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    VK-28

    CAS:
    VK-28 is a brain permeable iron chelator with neuroprotection. VK-28 inhibits basal as well as iron-induced mitochondrial lipid peroxidation.
    Formula:C16H21N3O2
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:287.36

    Ref: TM-T9956

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    EGFR/BRAFV600E-IN-4

    <p>EGFR/BRAFV600E-IN-4 (Compound 10f) is a dual inhibitor of EGFR and BRAFV600E, with IC50 values of 61 nM and 43 nM, respectively. It halts the cell cycle, induces apoptosis in both early and late stages, and inhibits cancer cell growth in vitro, showing broad-spectrum anticancer activity.</p>
    Formula:C22H16N4OS
    Color and Shape:Solid
    Molecular weight:384.45

    Ref: TM-T205664

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    Mcl-1 inhibitor 16

    Mcl-1 Inhibitor 16 (Compound 9), a platinum-based mitochondrial-targeting agent, inhibits Mcl-1 and induces Bax/Bak-dependent apoptosis in cancer cells.
    Formula:C25H29Cl2N3Pt
    Color and Shape:Solid
    Molecular weight:637.51

    Ref: TM-T79242

  • Z-VDVA-(DL-Asp)-FMK
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    Z-VDVA-(DL-Asp)-FMK

    CAS:
    Z-VDVA-(DL-Asp)-FMK is a derivative compound of Z-VDVAD-FMK specifically designed as an inhibitor targeting caspase-2.
    Formula:C32H46FN5O11
    Color and Shape:Solid
    Molecular weight:695.742

    Ref: TM-T39344