Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(93 products)
- c-RET(62 products)
- p53(63 products)
Show 6 more subcategories
Found 6064 products of "Apoptosis"
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GPX4-IN-6
CAS:GPX4-IN-6 is a GPX4 inhibitor with antitumor activity.GPX4-IN-6 induces iron death and is used for the treatment and prevention of triple-negative breast cancerFormula:C18H17BrFNO5Purity:99.54%Color and Shape:SoildMolecular weight:426.23HSP90-IN-18
HSP90-IN-18 inhibits Hsp90 with 0.39 μM IC50, useful for viral, neurodegenerative, and inflammatory research.Formula:C25H33FO3Color and Shape:SolidMolecular weight:400.53Arisostatin A
CAS:Arisostatin A is a secondary metabolite produced by microorganisms, recognized as an antibiotic (antibiotic) with activity against Gram-positive bacteria. This compound also exhibits potent antitumor properties. It induces apoptosis (apoptosis) by activating caspase-3 and generating reactive oxygen species (ROS) in AMC-HN-4 cells.Formula:C69H100N2O24Color and Shape:SolidMolecular weight:1341.53Met-12
CAS:Met-12 is a peptide inhibitor of the Fas receptor. It suppresses Fas receptor-mediated apoptosis in photoreceptor cells and reduces Caspase activation, making it a potential candidate for research on photoreceptor protectants.Formula:C71H99N17O17Color and Shape:SolidMolecular weight:1462.65Cyanoacetamide
CAS:Cyanoacetamide has inhibitory activity against the myeloid leukaemia cell differentiation protein Mcl-1Formula:C3H4N2OPurity:97.04%Color and Shape:Needles From Alcohol White To Light Cream Crystalline PowderMolecular weight:84.08CDK9-IN-24
CDK9-IN-24 (compound 21a) is a potent and selective inhibitor of CDK9 that exhibits a pronounced inhibitory impact on tumor proliferation.Formula:C27H31N3O4Purity:98%Color and Shape:SolidMolecular weight:461.55Prodigiosin hydrochloride
CAS:<p>Prodigiosin hydrochloride is a bioactive red pigment from bacteria with antibacterial, antifungal, anticancer properties, and inhibits Wnt/β-catenin.</p>Formula:C20H26ClN3OColor and Shape:SolidMolecular weight:359.9JC2-11
CAS:<p>JC2-11 is an anti-inflammatory agent blocking NLRC 4, AIM 2, ROS production, caspase-1 activity, and reducing GSDMD, IL-1β, and LDH in vesicles.</p>Formula:C17H15FO4Purity:98.6%Color and Shape:SoildMolecular weight:302.3BIO8898
BIO8898: potent CD40-CD154 inhibitor, IC50 of 25 µM, prevents CD40L-induced apoptosis.Formula:C53H64N8O6Color and Shape:SolidMolecular weight:909.13Flavopiridol
CAS:Flavopiridol (Alvocidib) blocks CDK1/2/4/6 by competing with ATP (IC50 ~40 nM); 7.5x selectivity over CDK7; also inhibits EGFR, PKA. In Phase 1/2 trials.Formula:C21H20ClNO5Purity:97.74% - 99.99%Color and Shape:SolidMolecular weight:401.84ILS-920
CAS:ILS-920, a Rapamycin analog, has reduced immunosuppression, enhanced neuroprotection, and preferentially binds FKBP52 and L-type VGCC β1.Formula:C57H86N2O14Purity:98%Color and Shape:SolidMolecular weight:1023.3Antitumor agent-100 hydrochloride
CAS:Antitumor agent-100 hydrochloride (compound A6), serving as both an apoptosis inducer and molecular glue, exhibits superior anti-tumor activity [1].Formula:C17H15Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:348.23ZS3-046
<p>ZS3-046 is a TAF1 PROTAC degrader that facilitates the ubiquitination and subsequent degradation of TAF1. It can activate p53 and induce apoptosis in acute myeloid leukemia (AML) cells. Additionally, ZS3-046 demonstrates anti-tumor efficacy in AML xenograft mouse models.</p>Formula:C49H57N9O7Color and Shape:SolidMolecular weight:883.4381Trichostatin C
CAS:Trichostatin C, a natural glycosylated hydroxamate, is a histone deacetylase inhibitor with antifungal properties and can induce cell differentiation.Formula:C23H32N2O8Color and Shape:SolidMolecular weight:464.515MS41
CAS:MS41 is a selective eleven-nineteen leukemia (ENL) PROTAC degrader, with DC50s values of 3.50 nM (MV4;11), 2.84 nM (SEMK2), 3.03 nM (Jurkat), and 26.58 nM (KASUMI1). This compound effectively inhibits the growth of ENL-dependent leukemia cells, induces G1 cell cycle arrest, and increases cellular apoptosis (Apoptosis). Additionally, MS41 reduces chromatin occupancy related to ENL-mediated transcription elongation mechanisms and suppresses the expression of oncogenes and the progression of leukemia.Formula:C56H70N8O9SColor and Shape:SolidMolecular weight:1031.27Galloflavin Potassium
CAS:Galloflavin Potassium is an inhibitor of lactate dehydrogenase.Formula:C12H5KO8Color and Shape:SolidMolecular weight:316.26Photosensitizer-6
CAS:<p>Photosensitizer-6 (Compound 4) is a metal ion complex that inhibits TrxR. It induces apoptosis in 4T1 cells, targeting cancer cells and eliminating tumors through chemophototherapy and immunogenic cell death under illumination. Additionally, Photosensitizer-6 can be utilized for tumor imaging.</p>Formula:C47H35AuF6N4P2SColor and Shape:SolidMolecular weight:1060.78Bleomycin A5
CAS:Bleomycin A5, or Pingyangmycin, is an oral glycopeptide antibiotic and acts as an antineoplastic and apoptosis inducer.Formula:C57H89N19O21S2Color and Shape:SolidMolecular weight:1440.56Diethanolamine hydrochloride
CAS:Diethanolamine hydrochloride is HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4) and pregnane X receptor (PXR), p53 Estrogen receptor.Formula:C4H12ClNO2Purity:99.69%Color and Shape:SolidMolecular weight:141.6NA-Ir
CAS:NA-Ir is a ferroptosis (Ferroptosis) inducer that targets mitochondrial DNA (mtDNA) and activates the cGAS-STING pathway to stimulate ferritin autophagy (). It also induces the production of reactive oxygen species (ROS) through photodynamic therapy (PDT), depletes glutathione (GSH), and downregulates glutathione peroxidase 4 (GPX4), thereby triggering lipid peroxidation and ferroptosis. NA-Ir exhibits enhanced anticancer activity under light exposure and selectively inhibits cancer cells with high H2S content.Formula:C49H36F6IrN8O4PColor and Shape:SolidMolecular weight:1138.04
