Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(6 products)
- Caspase(151 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(106 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(59 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6041 products of "Apoptosis"
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TV 3279
CAS:TV 3279 is a ChE-MAI inhibitor with neuroprotection via anti-apoptotic protein induction and blocks pro-apoptotic enzymes in cells.
Formula:C16H20N2O2Purity:97%Color and Shape:SoildMolecular weight:272.34Antitumor photosensitizer-3
Antitumor Photosensitizer-3 (Compound I), a chlorin derivative, effectively induces apoptosis and necrosis in tumor cells upon exposure to 650 nm laserFormula:C48H34N4O4Color and Shape:SolidMolecular weight:730.81N-Stearoyltyrosine
CAS:N-Stearoyltyrosine (N-(1-Oxooctadecyl)-L-tyrosine) is an analog of Anandamide. It exhibits neuroprotective effects by safeguarding the CA1 region of the hippocampus in a gerbil ischemia-reperfusion model. Additionally, N-Stearoyltyrosine inhibits free radical generation, enhances antioxidant capacity, and reduces IR-induced apoptosis (cell apoptosis).Formula:C27H45NO4Color and Shape:SolidMolecular weight:447.65c-JUN peptide
CAS:Peptide from c-Jun (33-57) blocks JNK binding, inhibits phosphorylation, upregulates p21, and induces HeLa cell apoptosis.
Formula:C121H210N36O34SPurity:98%Color and Shape:SolidMolecular weight:2743.55Antitumor agent-36
Antitumor agent-36: potent anti-cancer; causes DNA damage, triggers apoptosis, enhances immune response by upregulating T cells.Formula:C32H30Cl2N2O6PtColor and Shape:SolidMolecular weight:804.58Bursehernin
CAS:Bursehernin is a useful organic compound for research related to life sciences and the catalog number is T124894.Formula:C21H22O6Color and Shape:SolidMolecular weight:370.401(Rac)-AMXT-1501 4HCl
CAS:AMXT-1501 tetrahydrochloride is an inhibitor of polyamine transport.Formula:C32H72Cl4N6O2Purity:98.31%Color and Shape:SolidMolecular weight:714.77Asparanin A
CAS:Asparanin A, an apoptosis inducer with anticancer properties, arrests the cell cycle in the G0/G1 phase via the mitochondria and PI3K/AKT signaling pathways.Formula:C39H64O13Purity:98%Color and Shape:SolidMolecular weight:740.92Caerin 1.1 TFA
Caerin 1.1 TFA, a host defense peptide derived from the Australian tree frog Litoria's glandular secretions, exhibits anti-proliferative effects on HeLa cellsPurity:98%Color and Shape:Odour SolidAra-SH
Ara-SH, a derivative of Cytarabine with a mercaptopropionic acid substitution, serves as the initiator for the self-assembly of a smart, co-loaded CytarabineFormula:C12H17N3O6SPurity:98%Color and Shape:SolidMolecular weight:331.342'-epi-2'-O-Acetylthevetin B
CAS:2'-Epi-2'-O-Acetylthevetin B (GHSC-74), a cardiac glycoside extractable from Cerbera manghas L.Formula:C44H68O19Purity:98%Color and Shape:SolidMolecular weight:901PDL1 degrader-2
PD-L1degrader-2 (Compound B3) is an orally effective AUTAC degrader that degrades PD-L1 via the autophagy-lysosome pathway with a DC50 of 0.5 μM. It inhibits the interaction between PD-1 and PD-L1, with an IC50 of 22.8 nM. PD-L1degrader-2 upregulates the expression of Atg9b, Lamp1, and Mitf, activating the autophagy-lysosome system. It exhibits antitumor activity in the CT26 mouse model.Formula:C45H48N8O5Color and Shape:SolidMolecular weight:780.91CDK-IN-14
CDK-IN-14 (B34) is a CDK2 inhibitor (IC50=0.097 μM) that exhibits anti-hepatocellular carcinoma activity. It inhibits the cell cycle in HepG-2 cancer cells and induces apoptosis (apoptosis) through a caspase-mediated mechanism.Color and Shape:Odour SolidEstradiol (cypionate)
CAS:Estradiol cypionate (Depofemin), the 17 β-cyclopentylpropinate ester of estradiol, inhibits ET-1 synthesis via estrogen receptor.Formula:C26H36O3Purity:99.53% - >99.99%Color and Shape:White Or Off-White Crystalline PowderMolecular weight:396.56DL-Sulforaphane N-acetyl-L-cysteine
CAS:DL-Sulforaphane N-acetyl-L-cysteine (SFN-NAC), induces apoptosis through α-microtubulin and phosphorylation of ERK1/2-mediated Stathmin-1, and Hsp70 (NSCLC).Formula:C11H20N2O4S3Purity:99%Color and Shape:SolidMolecular weight:340.48NLRP3-IN-60
NLRP3-IN-60 (Compound 39) is an orally bioavailable inhibitor of NLRP3. It effectively suppresses pyroptosis in THP-1 cells with an IC50 of 13 nM and inhibits IL-1β release in human whole blood, exhibiting an IC50 of 225 nM.
Formula:C23H24F2N4O4SColor and Shape:SolidMolecular weight:490.523XIAP BIR2/BIR2-3 inhibitor-3
CAS:XIAP BIR2/BIR2-3 Inhibitor-3 functions as a dual inhibitor targeting both BIR2 and BIR2-3 domains, exhibiting potent activity with IC50 values below 1 nM. This compound is utilized in cancer research [1].Formula:C86H106N18O16S2Color and Shape:SolidMolecular weight:1712RD-23
CAS:RD-23 is an orally active and selective RET PROTAC degrader. It facilitates the ubiquitination and degradation of the RETG810C mutant with a DC50 value of 11.7 nM. Additionally, RD-23 inhibits the activation of downstream Shc signaling and induces apoptosis (Apoptosis). It is useful for studying RET-related cancers.Formula:C52H56N12O4Color and Shape:SolidMolecular weight:913.079Anticancer agent 132
Compound Rh1 (Anticancer agent 132) acts as an inducer of apoptosis and autophagy, exhibiting both antitumor and antimetastatic activities.Formula:C24H16Cl3F3N5ORhPurity:98%Color and Shape:SolidMolecular weight:656.68HPCR
CAS:HPCR exhibits antiproliferative activity against various cancer cells and is involved in apoptosis (apoptosis).Formula:C52H40O12Color and Shape:SolidMolecular weight:856.867
