
Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(127 products)
- FOXO1(3 products)
- IAP(65 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(24 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(91 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5622 products of "Apoptosis"
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YCH3124
<p>YCH3124 (compound Z33) is an inhibitor of USP7, exhibiting anti-tumor activity with an IC50 value of 41.9 nM. This compound demonstrates substantial in vitro anti-proliferative effects on various tumor cells, including LNCaP (IC50= 3.6 nM) and CHP-212 (IC50=9.9 nM). Moreover, YCH3124 induces apoptosis in CHP-212 cells by disrupting the cell cycle process during the G1 phase.</p>Formula:C30H34N4O5Color and Shape:SolidMolecular weight:530.61Thalidomide-O-C8-COOH
CAS:<p>Thalidomide-O-C8-COOH, also known as Cereblon ligand 3, is a Thalidomide-derived compound that serves as a Cereblon (CRBN) ligand for the targeted recruitment</p>Formula:C22H26N2O7Color and Shape:SolidMolecular weight:430.4513-Methyltetradecanoic acid
CAS:<p>LeDSF3 controls HSAF production in Lysobacter, has antifungal properties, and acts as an anti-tumor by inhibiting p-AKT and activating caspase-3.</p>Formula:C15H30O2Color and Shape:SolidMolecular weight:242.4Thalidomide-5-CH2-NH2 hydrochloride
CAS:<p>Thalidomide-5-CH2-NH2 (HCl) recruits CRBN protein, used to create PROTACs via a linker.</p>Formula:C14H14ClN3O4Color and Shape:SolidMolecular weight:323.73Ezatiostat
CAS:<p>Ezatiostat (TER199(free base)) is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity.</p>Formula:C27H35N3O6SPurity:97.95%Color and Shape:SolidMolecular weight:529.65Isoscabertopin
CAS:<p>Isoscabertopin has anticancer activity.</p>Formula:C20H22O6Purity:98%Color and Shape:SolidMolecular weight:358.39ML-291
CAS:<p>ML291 triggers UPR, causing apoptosis in solid cancers by activating PERK/eIF2a/CHOP pathway and reducing leukemia cells.</p>Formula:C16H16ClN3O6SColor and Shape:SolidMolecular weight:413.83Mepazine hydrochloride
CAS:<p>Mepazine hydrochloride (Pecazine hydrochloride) is a MALT1 inhibitor with anticancer and antitumor activity, inhibiting RANK-induced osteoclastogenesis.</p>Formula:C19H23ClN2SPurity:99.76%Color and Shape:SolidMolecular weight:346.92PR-924
CAS:PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM).Formula:C37H38N4O5Purity:98%Color and Shape:SolidMolecular weight:618.72AK-778-XXMU
CAS:<p>AK-778-XXMU is an ID2 antagonist with a KD value of 129 nM.AK-778-XXMU has potential antitumor and anticancer activity and can be used for the study of gliomas.</p>Formula:C22H17ClN2O3Purity:>99.99%Color and Shape:SolidMolecular weight:392.835PBOX 6
CAS:<p>PBOX 6 is a pyrrolo-1,5-benzoxazepine (PBOX) compound with anticancer and antitumor activity that inhibits the growth of breast cancer cells.</p>Formula:C25H20N2O3Purity:98.18% - 98.71%Color and Shape:SolidMolecular weight:396.44Rutin trihydrate
CAS:<p>Rutin trihydrate is a natural flavonoid with antioxidant, anti-inflammatory, anti-diabetic, and anti-cancer benefits, plus heart and brain protection.</p>Formula:C27H36O19Color and Shape:SolidMolecular weight:664.56OTS193320
CAS:<p>OTS193320, an imidazo[1,2-a]pyridine, inhibits SUV39H2, reduces H3K9me3, and induces apoptosis in breast cancer; enhances DOX effects.</p>Formula:C28H30ClN5O4Color and Shape:SolidMolecular weight:536.02Ancitabine
CAS:<p>Ancitabine is an antitumour drug that improves Hailey-Hailey disease-related phenotypes in yeast models. inhibits DNA synthesis, acute leukaemia.</p>Formula:C9H11N3O4Purity:99.91%Color and Shape:SolidMolecular weight:225.2Pexidartinib hydrochloride
CAS:<p>Pexidartinib HCl is a potent, selective CSF1R and c-Kit inhibitor with IC50s of 20 nM and 10 nM, respectively, showing anti-tumor activity.</p>Formula:C20H16Cl2F3N5Color and Shape:SolidMolecular weight:454.28Sunitinib-d10
CAS:<p>Sunitinib D10, a deuterium-enriched version, inhibits VEGFR2 and PDGFRβ tyrosine kinases (IC50: 80 nM/2 nM).</p>Formula:C22H27FN4O2Purity:98%Color and Shape:SolidMolecular weight:408.54Vitamin E succinate
CAS:Vitamin E succinate (D-alpha-Tocopherol Succinate) is an antioxidant tocopherol with antitumor activity that induces apoptosis.Formula:C33H54O5Purity:99.24%Color and Shape:SolidMolecular weight:530.78SC144 hydrochloride
CAS:<p>SC144 hydrochloride: oral gp130 inhibitor, blocks Stat3 and gene expression, triggers apoptosis in ovarian cancer cells.</p>Formula:C16H12ClFN6OColor and Shape:SolidMolecular weight:358.76Glucagon-Like Peptide (GLP) II, human
CAS:GLP-2, an intestinal growth factor, may treat various human intestinal diseases.Formula:C165H254N44O55SColor and Shape:SolidMolecular weight:3766.2Thalidomide-piperazine hydrochloride
CAS:<p>Thalidomide-piperazine HCl may aid leprosy, multiple myeloma research, and developmental biology studies.</p>Formula:C17H19ClN4O4Color and Shape:SolidMolecular weight:378.81

