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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 5622 products of "Apoptosis"

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  • YCH3124


    <p>YCH3124 (compound Z33) is an inhibitor of USP7, exhibiting anti-tumor activity with an IC50 value of 41.9 nM. This compound demonstrates substantial in vitro anti-proliferative effects on various tumor cells, including LNCaP (IC50= 3.6 nM) and CHP-212 (IC50=9.9 nM). Moreover, YCH3124 induces apoptosis in CHP-212 cells by disrupting the cell cycle process during the G1 phase.</p>
    Formula:C30H34N4O5
    Color and Shape:Solid
    Molecular weight:530.61
  • Thalidomide-O-C8-COOH

    CAS:
    <p>Thalidomide-O-C8-COOH, also known as Cereblon ligand 3, is a Thalidomide-derived compound that serves as a Cereblon (CRBN) ligand for the targeted recruitment</p>
    Formula:C22H26N2O7
    Color and Shape:Solid
    Molecular weight:430.45
  • 13-Methyltetradecanoic acid

    CAS:
    <p>LeDSF3 controls HSAF production in Lysobacter, has antifungal properties, and acts as an anti-tumor by inhibiting p-AKT and activating caspase-3.</p>
    Formula:C15H30O2
    Color and Shape:Solid
    Molecular weight:242.4
  • Thalidomide-5-CH2-NH2 hydrochloride

    CAS:
    <p>Thalidomide-5-CH2-NH2 (HCl) recruits CRBN protein, used to create PROTACs via a linker.</p>
    Formula:C14H14ClN3O4
    Color and Shape:Solid
    Molecular weight:323.73
  • Ezatiostat

    CAS:
    <p>Ezatiostat (TER199(free base)) is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity.</p>
    Formula:C27H35N3O6S
    Purity:97.95%
    Color and Shape:Solid
    Molecular weight:529.65
  • Isoscabertopin

    CAS:
    <p>Isoscabertopin has anticancer activity.</p>
    Formula:C20H22O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:358.39
  • ML-291

    CAS:
    <p>ML291 triggers UPR, causing apoptosis in solid cancers by activating PERK/eIF2a/CHOP pathway and reducing leukemia cells.</p>
    Formula:C16H16ClN3O6S
    Color and Shape:Solid
    Molecular weight:413.83
  • Mepazine hydrochloride

    CAS:
    <p>Mepazine hydrochloride (Pecazine hydrochloride) is a MALT1 inhibitor with anticancer and antitumor activity, inhibiting RANK-induced osteoclastogenesis.</p>
    Formula:C19H23ClN2S
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:346.92
  • PR-924

    CAS:
    PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM).
    Formula:C37H38N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:618.72
  • AK-778-XXMU

    CAS:
    <p>AK-778-XXMU is an ID2 antagonist with a KD value of 129 nM.AK-778-XXMU has potential antitumor and anticancer activity and can be used for the study of gliomas.</p>
    Formula:C22H17ClN2O3
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:392.835
  • PBOX 6

    CAS:
    <p>PBOX 6 is a pyrrolo-1,5-benzoxazepine (PBOX) compound with anticancer and antitumor activity that inhibits the growth of breast cancer cells.</p>
    Formula:C25H20N2O3
    Purity:98.18% - 98.71%
    Color and Shape:Solid
    Molecular weight:396.44
  • Rutin trihydrate

    CAS:
    <p>Rutin trihydrate is a natural flavonoid with antioxidant, anti-inflammatory, anti-diabetic, and anti-cancer benefits, plus heart and brain protection.</p>
    Formula:C27H36O19
    Color and Shape:Solid
    Molecular weight:664.56
  • OTS193320

    CAS:
    <p>OTS193320, an imidazo[1,2-a]pyridine, inhibits SUV39H2, reduces H3K9me3, and induces apoptosis in breast cancer; enhances DOX effects.</p>
    Formula:C28H30ClN5O4
    Color and Shape:Solid
    Molecular weight:536.02
  • Ancitabine

    CAS:
    <p>Ancitabine is an antitumour drug that improves Hailey-Hailey disease-related phenotypes in yeast models. inhibits DNA synthesis, acute leukaemia.</p>
    Formula:C9H11N3O4
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:225.2
  • Pexidartinib hydrochloride

    CAS:
    <p>Pexidartinib HCl is a potent, selective CSF1R and c-Kit inhibitor with IC50s of 20 nM and 10 nM, respectively, showing anti-tumor activity.</p>
    Formula:C20H16Cl2F3N5
    Color and Shape:Solid
    Molecular weight:454.28
  • Sunitinib-d10

    CAS:
    <p>Sunitinib D10, a deuterium-enriched version, inhibits VEGFR2 and PDGFRβ tyrosine kinases (IC50: 80 nM/2 nM).</p>
    Formula:C22H27FN4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:408.54
  • Vitamin E succinate

    CAS:
    Vitamin E succinate (D-alpha-Tocopherol Succinate) is an antioxidant tocopherol with antitumor activity that induces apoptosis.
    Formula:C33H54O5
    Purity:99.24%
    Color and Shape:Solid
    Molecular weight:530.78
  • SC144 hydrochloride

    CAS:
    <p>SC144 hydrochloride: oral gp130 inhibitor, blocks Stat3 and gene expression, triggers apoptosis in ovarian cancer cells.</p>
    Formula:C16H12ClFN6O
    Color and Shape:Solid
    Molecular weight:358.76
  • Glucagon-Like Peptide (GLP) II, human

    CAS:
    GLP-2, an intestinal growth factor, may treat various human intestinal diseases.
    Formula:C165H254N44O55S
    Color and Shape:Solid
    Molecular weight:3766.2
  • Thalidomide-piperazine hydrochloride

    CAS:
    <p>Thalidomide-piperazine HCl may aid leprosy, multiple myeloma research, and developmental biology studies.</p>
    Formula:C17H19ClN4O4
    Color and Shape:Solid
    Molecular weight:378.81