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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 5618 products of "Apoptosis"

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  • HNPMI
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    HNPMI

    CAS:
    <p>HNPMI is an epidermal growth factor receptor inhibitor that promotes apoptosis and is used in the study of colorectal cancer.</p>
    Formula:C22H20N2O3
    Purity:97.19%
    Color and Shape:Soild
    Molecular weight:360.41

    Ref: TM-T83641

  • RMC-9805
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    RMC-9805

    CAS:
    <p>RMC-9805(Zoldonrasib) is a KRAS G12D inhibitor with anti-tumor and anti-proliferative activity for the study of pancreatic cancer.</p>
    Formula:C63H88F3N11O7
    Purity:98.10% - 99.51%
    Color and Shape:Solid
    Molecular weight:1168.44

    Ref: TM-T78212

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    Nrf2 activator 19

    <p>Nrf2 activator 19 is a compound capable of crossing the blood-brain barrier and acts as an NRF2/HO-1 activator, offering potent antioxidant and neuroprotective effects. It effectively reduces brain damage and minimizes the accumulation of Reactive Oxygen Species (ROS). Additionally, Nrf2 activator 19 inhibits neuronal apoptosis, aiding in the recovery of neural function and motor skills. It has demonstrated significant potential in ischemic stroke research.</p>
    Color and Shape:Odour Solid

    Ref: TM-T206271

  • Z-Ala-Ala-Asp-CMK
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    Z-Ala-Ala-Asp-CMK

    CAS:
    <p>Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor that blocks granzyme B protease activity, for inflammatory diseases and tumours.</p>
    Formula:C19H24ClN3O7
    Purity:99.967%
    Color and Shape:Solid
    Molecular weight:441.86

    Ref: TM-T80745

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    Spexin TFA

    <p>Spexin TFA: GAL2/GAL3 agonist (EC50: 45.7/112.2 nM), no activity at GAL1, reduces appetite, fatty acid uptake, and LH secretion; anxiolytic.</p>
    Formula:C76H115F3N20O21S
    Color and Shape:Solid
    Molecular weight:1733.9

    Ref: TM-T76002

  • YB-0158 ammonium
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    YB-0158 ammonium

    <p>YB-0158 ammonium (Wnt pathway inhibitor 2 ammonium) is a reverse-rotation peptidomimetic with translation-enhancing potential and anticancer activity.</p>
    Formula:C32H40N9O7P
    Purity:99.14% - 99.18%
    Color and Shape:Solid
    Molecular weight:693.69

    Ref: TM-T38519L

  • Chaetoglobosin A
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    Chaetoglobosin A

    CAS:
    Chaetoglobosin A, the active compound extracted of Penicillium aquamarinium, is a member of the cytochalasan family. It preferentially induces apoptosis.
    Formula:C32H36N2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:528.649

    Ref: TM-T13608

  • 2-Acetamidophenol
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    2-Acetamidophenol

    CAS:
    <p>2-Acetamidophenol (Orthocetamol) has analgesic and antipyretic effects. 2-Acetamidophenol is an isomer of Paracetamol (4-acetamidophenol).</p>
    Formula:C8H9NO2
    Purity:>99.99%
    Color and Shape:Light Brown Powder
    Molecular weight:151.16

    Ref: TM-T7238

  • Reproxalap
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    Reproxalap

    CAS:
    <p>Reproxalap (NS-2) is a dry eye treatment that neutralizes aldehydes like malondialdehyde.</p>
    Formula:C12H13ClN2O
    Purity:99.4% - 99.97%
    Color and Shape:Solid
    Molecular weight:236.7

    Ref: TM-T16732

  • Oxatomide
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    Oxatomide

    CAS:
    <p>Oxatomide: Dual H1/P2X7 antagonist, antihistamine, anti-allergic, treats immune diseases, IC50: 0.95 μM (P2X7), 0.43 μM (5-HT).</p>
    Formula:C27H30N4O
    Purity:98.82% - 99.72%
    Color and Shape:White Powder
    Molecular weight:426.55

    Ref: TM-T19839

  • Waltonitone
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    Waltonitone

    CAS:
    <p>Waltonitone is a natural ursane-type pentacyclic triterpene isolated from Gentian waltonii Burkill.</p>
    Formula:C30H48O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:440.7

    Ref: TM-T13964

  • Enniatin complex
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    Enniatin complex

    CAS:
    <p>Enniatin complex: fungal cyclohexadepsipeptides inhibit enzymes, induce cancer cell apoptosis, and have ionophoric, antibiotic, and hypolipidemic effects.</p>
    Purity:98%
    Color and Shape:Solid

    Ref: TM-T11202

  • Ferroptosis-IN-13
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    Ferroptosis-IN-13

    <p>Ferroptosis-IN-13 (compound NY-26) is an inhibitor of ferroptosis. It effectively suppresses RSL3-induced ferroptosis in 786-O cells, with an EC50 value of 62 nM.</p>
    Formula:C32H30F2N4O3
    Color and Shape:Solid
    Molecular weight:556.602

    Ref: TM-T206774

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    FPR1 antagonist 2

    <p>Compound 25b, an FPR1 antagonist, exhibits potent inhibition of the formyl peptide receptor 1 with an IC50 of 70 nM.</p>
    Formula:C25H25F3O5
    Color and Shape:Solid
    Molecular weight:462.46

    Ref: TM-T79782

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    Ianalumab

    CAS:
    <p>Ianalumab (VAY-736) is a decarboxylated humanized antibody against BAFF-R.</p>
    Purity:100% (SEC-HPLC) - > 95%
    Color and Shape:Liquid
    Molecular weight:146.44 kDa

    Ref: TM-T77370

  • KB03-SLF
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    KB03-SLF

    CAS:
    <p>KB03-SLF is a protease with the capability to target specific proteins and regulate intracellular protein levels by inducing protein degradation. This mechanism renders KB03-SLF potentially valuable in the suppression of related diseases.</p>
    Formula:C50H63ClF3N5O12
    Color and Shape:Solid
    Molecular weight:1018.51

    Ref: TM-T201318

  • WAY-118959-A
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    WAY-118959-A

    CAS:
    <p>WAY-118959-A is a potential microtubule acetylation inhibitor.</p>
    Formula:C16H14N4OS2
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:342.44

    Ref: TM-T60065

  • Sorafenib-d4
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    Sorafenib-d4

    CAS:
    <p>Sorafenib D4 is deuterium-labeled Sorafenib, a multi-kinase inhibitor (Raf-1, B-Raf, VEGFR-3) with IC50s: 6, 20, 22 nM.</p>
    Formula:C21H16ClF3N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:468.85

    Ref: TM-T12976

  • Thalidomide-PEG2-NH2
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    Thalidomide-PEG2-NH2

    CAS:
    <p>Thalidomide-PEG2-NH2: synthetic E3 ligase ligand-linker, combines Thalidomide-based cereblon and PROTAC linker.</p>
    Formula:C17H19N3O6
    Color and Shape:Solid
    Molecular weight:361.354

    Ref: TM-T39377

  • Taltirelin acetate
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    Taltirelin acetate

    CAS:
    <p>Taltirelin acetate (TA-0910 acetate) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an</p>
    Formula:C19H27N7O7
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:465.46

    Ref: TM-T13072

  • Neocarzinostatin
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    Neocarzinostatin

    CAS:
    <p>Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.</p>
    Purity:98%
    Color and Shape:Solid
    Molecular weight:N/A

    Ref: TM-T16283

  • 1,8-Cineole
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    1,8-Cineole

    CAS:
    <p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>
    Formula:C10H18O
    Purity:97.44% - 97.44%
    Color and Shape:Solid
    Molecular weight:154.25

    Ref: TM-T1714

  • MTX-23
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    MTX-23

    CAS:
    MTX-23, an AR-targeted Proteolysis Targeting Chimera (PROTAC), effectively degrades both AR-V7 and AR-FL, inhibiting the proliferation of CaP cells and inducing
    Formula:C43H53F2N7O7S2
    Color and Shape:Solid
    Molecular weight:882.05

    Ref: TM-T74744

  • (R)-JAK2/STAT3-IN-10a
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    (R)-JAK2/STAT3-IN-10a

    CAS:
    <p>(R)-JAK2/STAT3-IN-10a is the R-isomer of JAK2/STAT3-IN-1.JAK2/STAT3-IN-1 is a structural domain inhibitor of GP130 D1 with antitumor activity.</p>
    Formula:C34H35BrF3N5O2
    Purity:97.99%
    Color and Shape:Soild
    Molecular weight:682.57

    Ref: TM-T72754L

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    NMC-001

    <p>NMC-001 is a human IgG1 monoclonal antibody (mAb) that targets MDM2. It is useful for pancreatic cancer research. The recommended isotype control is HumanIgG1kappa, Isotype Control.</p>
    Color and Shape:Odour Liquid

    Ref: TM-T9901A-1077

  • Conophylline
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    Conophylline

    CAS:
    <p>Conophylline, an alkaloid from Ervatamia microphylla, induces pancreatic cell differentiation and apoptosis, and suppresses HSC.</p>
    Formula:C44H50N4O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:794.89

    Ref: TM-T13624

  • Verdinexor
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    Verdinexor

    CAS:
    <p>Verdinexor (KPT-335) (KPT-335), a specific XPO1/CRM1 inhibitor, are orally bioavailable.</p>
    Formula:C18H12F6N6O
    Purity:98% - 99.68%
    Color and Shape:Solid
    Molecular weight:442.32

    Ref: TM-T6123

  • HTR2A antagonist 1
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    HTR2A antagonist 1

    <p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>
    Formula:C35H43Cl2F2N5O4
    Color and Shape:Solid
    Molecular weight:706.65

    Ref: TM-T204966

  • Resolvin D2 n-3 DPA
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    Resolvin D2 n-3 DPA

    CAS:
    <p>RvD2 n-3 DPA is an SPM made from docosapentaenoic acid in human leukocytes, inhibiting neutrophil chemotaxis and adhesion.</p>
    Formula:C22H34O5
    Color and Shape:Solid
    Molecular weight:378.509

    Ref: TM-T37289

  • PD-1/PD-L1-IN-49
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    PD-1/PD-L1-IN-49

    <p>PD-1/PD-L1-IN-49 (compound 1c) is a potent inhibitor of PD-1/PD-L1 with an IC50 of 77 nM. This compound can activate Jurkat T cells and effectively block the PD-1/PD-L1 immune checkpoint.</p>
    Formula:C27H32N4O5
    Color and Shape:Solid
    Molecular weight:492.567

    Ref: TM-T206990

  • Azadirone
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    Azadirone

    CAS:
    <p>Azadirone, a limonoid, sensitizes cancer cells to TRAIL by modulating DR4/DR5, survival, and apoptotic proteins.</p>
    Formula:C9H15N3O5
    Color and Shape:Solid
    Molecular weight:245.23

    Ref: TM-T26709

  • Streptonigrin
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    Streptonigrin

    CAS:
    <p>Streptonigrin, from Streptomyces flocculus, has anti-tumor and anti-bacterial properties, inhibiting PAD1-4.</p>
    Formula:C25H22N4O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:506.46

    Ref: TM-T16946

  • Kusunokinin
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    Kusunokinin

    <p>Kusunokinin is a useful organic compound for research related to life sciences and the catalog number is T124612.</p>
    Formula:C21H22O6
    Color and Shape:Solid
    Molecular weight:370.401

    Ref: TM-T124612

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    TRBP-IN-1

    <p>TRBP-IN-1 (Compound 13j) is an orally active inhibitor of TAR RNA-binding protein 2 (TRBP) with an IC50 of 12.72 μM. It exhibits significant anti-hepatocellular carcinoma (HCC) activity, effectively suppressing proliferation and metastasis of HCC cells [HCCLM3 cells (IC50: 18.96 μM) and SK-Hep-1 cells (IC50: 16.45 μM)]. TRBP-IN-1 modulates miRNA biosynthesis by targeting TRBP, inhibiting the expression of oncogenic miRNAs. It induces apoptosis and pyroptosis in HCC cells by decreasing miRNA levels. TRBP-IN-1 is suitable for research on targeted HCC therapy.</p>
    Formula:C25H23F3N2O5S
    Color and Shape:Solid
    Molecular weight:520.12798

    Ref: TM-T207594

  • VK-28
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    VK-28

    CAS:
    <p>VK-28 is a brain permeable iron chelator with neuroprotection. VK-28 inhibits basal as well as iron-induced mitochondrial lipid peroxidation.</p>
    Formula:C16H21N3O2
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:287.36

    Ref: TM-T9956

  • (E/Z)-10-Hydroxy-2-decenoic acid
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    (E/Z)-10-Hydroxy-2-decenoic acid

    CAS:
    <p>(E/Z)-10-Hydroxy-2-decenoic acid is a useful organic compound for research related to life sciences.</p>
    Formula:C10H18O3
    Color and Shape:Solid
    Molecular weight:186.251

    Ref: TM-T124254

  • CST626
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    CST626

    CAS:
    <p>CST626 is a PROTAC degrader that targets XIAP, cIAP1, and cIAP2.</p>
    Formula:C61H82N8O9S
    Purity:95.87%
    Color and Shape:Solid
    Molecular weight:1103.42

    Ref: TM-T78947

  • NQO2-IN-1
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    NQO2-IN-1

    CAS:
    NQO2-IN-1, a resveratrol analog, is a potent NQO2 inhibito,antitumor,generation of ROS and up-regulation of DR5 (death receptor 5) to promote apoptosis.
    Formula:C18H18N2O3
    Purity:99.83%
    Color and Shape:Soild
    Molecular weight:310.35

    Ref: TM-T203013

  • AUNP-12
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    AUNP-12

    CAS:
    <p>AUNP-12, a new immune checkpoint modulator, is an inhibitor of the PD-1 pathway.</p>
    Formula:C142H226N40O48
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3261.55

    Ref: TM-TP1076

  • K-252c
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    K-252c

    CAS:
    <p>K-252c is a staurosporine analog isolated from Nocardiopsis sp.</p>
    Formula:C20H13N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:311.34

    Ref: TM-T15638

  • CNDAC hydrochloride
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    CNDAC hydrochloride

    CAS:
    <p>CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.</p>
    Formula:C10H13ClN4O4
    Purity:99.45%
    Color and Shape:Solid
    Molecular weight:288.69

    Ref: TM-T13621

  • Ceftiofur hydrochloride
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    Ceftiofur hydrochloride

    CAS:
    <p>Ceftiofur hydrochloride (U-67279A) is a stable, broad-spectrum 3rd-gen cephalosporin with antibacterial properties.</p>
    Formula:C19H17N5O7S3·HCl
    Purity:99.51%
    Color and Shape:Off-White Solid
    Molecular weight:560.02

    Ref: TM-T6268

  • Albicanol
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    Albicanol

    CAS:
    <p>Albicanol is a biochemical.</p>
    Formula:C15H26O
    Color and Shape:Solid
    Molecular weight:222.372

    Ref: TM-T29832

  • Methylene Violet 3RAX
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    Methylene Violet 3RAX

    CAS:
    <p>Methylene Violet 3RAX is a cationic dye that is a potential photosensitizer in photodynamic therapy and has antitumor activity.</p>
    Formula:C22H23ClN4
    Purity:97.03% - 97.17%
    Color and Shape:Solid
    Molecular weight:378.9

    Ref: TM-T77235

  • Bax inhibitor peptide, negative control
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    Bax inhibitor peptide, negative control

    CAS:
    <p>The compound is a negative control peptide for the Bax inhibitor peptides V5 and P5.</p>
    Formula:C28H52N6O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:600.81

    Ref: TM-TP2203

  • Thalidomide-NH-C10-COOH
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    Thalidomide-NH-C10-COOH

    <p>Compound 6b is a synthetic Thalidomide-VHL E3 ligase-linker for PROTACs.</p>
    Formula:C24H31N3O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:457.52

    Ref: TM-T18806

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    PPIA-IN-1

    <p>PPIA-IN-1 (Compound 20b) is an inhibitor of peptidyl-prolyl isomerase A (PPIA) with a KD of 0.52 μM. It demonstrates antiproliferative activity across various cancer cell lines, including an IC50 of 0.69 μM in HCT116 cells, induces cell cycle arrest at the G0/G1 phase, and exhibits antimetastatic effects in HCT116 cells. PPIA-IN-1 elevates ROS levels, causing DNA damage, ER stress, and mitochondrial dysfunction, and induces apoptosis in HCT116 cells via the MAPK pathway. Additionally, PPIA-IN-1 shows antitumor activity in a CT26 xenograft mouse model.</p>
    Formula:C23H21Cl2FN4O7
    Color and Shape:Solid
    Molecular weight:555.34

    Ref: TM-T205696

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    AKT-IN-18

    <p>AKT-IN-18, an Akt inhibitor, demonstrates an IC50 value of 69.45 μM in A549 cells, effectively impeding Akt activity.</p>
    Formula:C19H14ClN5O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:411.86

    Ref: TM-T78913

  • Mangafodipir trisodium
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    Mangafodipir trisodium

    CAS:
    <p>Mangafodipir trisodium can enhance contrast in magnetic resonance imaging (MRI) of the liver, is a contrast agent delivered intravenously.</p>
    Formula:C22H27MnN4Na3O14P2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:757.32

    Ref: TM-T19413

  • Tauro-β-muricholic acid
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    Tauro-β-muricholic acid

    CAS:
    <p>Tauro-β-muricholic acid (TβMCA), a trihydroxylated bile acid, acts as a competitive and reversible FXR antagonist (IC 50 = 40 μM) and exhibits antiapoptotic</p>
    Formula:C26H45NO7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:515.7

    Ref: TM-T81030