Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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TPEN
CAS:<p>TPEN (TPEDA) is a specific cell-permeable heavy metal chelator.</p>Formula:C26H28N6Purity:98% - 99.72%Color and Shape:White Crystalline PowderMolecular weight:424.54dl-Maackiain
CAS:<p>1. dl-Maackiain (Demethylpterocarpin) induces apoptosis and growth suppression 2. MAK1 is the second functional gene cloned from Maackiain detoxification.</p>Formula:C16H12O5Purity:97.36% - 99.89%Color and Shape:SolidMolecular weight:284.26G-749
CAS:<p>G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the FLT3 wild type and mutants.</p>Formula:C25H25BrN6O2Purity:98.32% - 99.60%Color and Shape:SolidMolecular weight:521.41Aurintricarboxylic acid
CAS:<p>Aurintricarboxylic acid (NSC-4056) blocks nucleases and topoisomerases, stopping nucleic acid binding.</p>Formula:C22H14O9Purity:97.1%Color and Shape:Deep Red Coarse Crystalline PowderMolecular weight:422.34Volasertib
CAS:<p>Volasertib (BI 6727) (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic arrest and apoptosis.</p>Formula:C34H50N8O3Purity:98% - 99.72%Color and Shape:SolidMolecular weight:618.81FIN56
CAS:<p>FIN56 is a specific inducer of ferroptosis.</p>Formula:C25H31N3O5S2Purity:99.72% - 99.78%Color and Shape:SolidMolecular weight:517.66Wedelolactone
CAS:<p>Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.</p>Formula:C16H10O7Purity:98.07% - 99.87%Color and Shape:SolidMolecular weight:314.25Calycosin
CAS:<p>Calycosin modulates estrogen receptors, induces apoptosis in cancers, and shows skin-lightening by inhibiting tyrosinase (IC50: 38.4µM).</p>Formula:C16H12O5Purity:99.91% - >99.99%Color and Shape:White PowderMolecular weight:284.26Amantadine
CAS:<p>Amantadine (1-Aminoadamantane), an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release and blocks dopamine reuptake.</p>Formula:C10H17NPurity:99.73% - 99.94%Color and Shape:Hexakistetrahedral Crystals By Sublimation SolidMolecular weight:151.25GSK1324726A
CAS:<p>GSK1324726A (I-BET726) is a greatly specific inhibitor of BET family proteins for BRD2(IC50=41 nM), BRD3(IC50=31 nM), and BRD4 (IC50=22 nM).</p>Formula:C25H23ClN2O3Purity:98.34% - 99.85%Color and Shape:SolidMolecular weight:434.91TCS-PIM-1-4a
CAS:<p>SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).</p>Formula:C11H6F3NO2SPurity:99.89%Color and Shape:SolidMolecular weight:273.23Dihydrorotenone
CAS:<p>Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.</p>Formula:C23H24O6Purity:98.98% - 99.58%Color and Shape:SolidMolecular weight:396.43PIK-75
CAS:<p>PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).</p>Formula:C16H14BrN5O4SPurity:98.52% - >99.99%Color and Shape:SolidMolecular weight:452.28Methyl protodioscin
CAS:<p>Methyl protodioscin boosts HDL, lowers LDL and triglycerides, has anti-cancer effects, and promotes apoptosis via mitochondrial pathways.</p>Formula:C52H86O22Purity:99.308% - 99.73%Color and Shape:SolidMolecular weight:1063.23VER-50589
CAS:<p>VER-50589 is a potent HSP90 inhibitor.</p>Formula:C19H17ClN2O5Purity:99.96% - >99.99%Color and Shape:SolidMolecular weight:388.8Aniline mustard
CAS:<p>Aniline mustard (Mesylerythrol) is alkylating mustard with anti-neoplastic activity.</p>Formula:C10H13Cl2NPurity:99.54%Color and Shape:SolidMolecular weight:218.12Fosbretabulin Disodium
CAS:<p>Fosbretabulin Disodium (CA 4P), a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM).</p>Formula:C18H19O8P·2NaPurity:97.43% - 99.96%Color and Shape:White SolidMolecular weight:440.29TAS6417
CAS:<p>Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.</p>Formula:C23H20N6OPurity:99.71%Color and Shape:SolidMolecular weight:396.444E1rcat
CAS:<p>4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.</p>Formula:C28H18N2O6Purity:99.47%Color and Shape:SolidMolecular weight:478.45Isatin
CAS:<p>Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor.</p>Formula:C8H5NO2Purity:98.92%Color and Shape:Yellow To Reddish Crystalline SolidMolecular weight:147.13Larotrectinib sulfate
CAS:<p>Larotrectinib sulfate (LOXO-101 sulfate) is an oral active and specific ATP-competitive inhibitor of tropomyosin receptor kinases (TRK).</p>Formula:C21H22F2N6O2·H2O4SPurity:98.62% - 99.76%Color and Shape:SolidMolecular weight:526.51UNC1215
CAS:<p>UNC1215, a potent MBT antagonist, targets L3MBTL3 with high selectivity (IC50: 40 nM, Kd: 120 nM, 50x versus MBT family).</p>Formula:C32H43N5O2Purity:98% - 99.04%Color and Shape:SolidMolecular weight:529.72Levomenol
CAS:<p>Levomenol, or (-)-α-Bisabolol, is a sesquiterpene in aromatic plant oils with antioxidant, anti-inflammatory, and anti-apoptotic properties.</p>Formula:C15H26OPurity:96.01%Color and Shape:Clear To Yellowish LiquidMolecular weight:222.37Isoalantolactone
CAS:<p>Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.</p>Formula:C15H20O2Purity:99.75% - 99.94%Color and Shape:SolidMolecular weight:232.32Zoledronic acid monohydrate
CAS:<p>Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.</p>Formula:C5H12N2O8P2Purity:99.91%Color and Shape:White To Off-White PowderMolecular weight:290.1Apremilast
CAS:<p>Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities.</p>Formula:C22H24N2O7SPurity:98.13% - 99.95%Color and Shape:SolidMolecular weight:460.50Polyporenic acid C
CAS:<p>Polyporenic acid C shows inhibitory activity against human collagenase.</p>Formula:C31H46O4Purity:96.84% - 99.71%Color and Shape:SolidMolecular weight:482.69Toddaculin
CAS:<p>Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the</p>Formula:C16H18O4Purity:99.91%Color and Shape:SolidMolecular weight:274.31Piperazine Erastin
CAS:<p>Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.</p>Formula:C35H41ClN6O4Purity:99.52%Color and Shape:SolidMolecular weight:645.19WHI-P154
CAS:<p>WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.</p>Formula:C16H14BrN3O3Purity:98% - 99.67%Color and Shape:SolidMolecular weight:376.2S63845
CAS:<p>S63845 is a selective myeloid leukemia 1（MCL1) inhibitor that binds to human MCL1 with a Kd of 0.19 nM.Cost-effective and quality-assured.</p>Formula:C39H37ClF4N6O6SPurity:97.7% - ≥98%Color and Shape:SolidMolecular weight:829.26Mdivi-1
CAS:<p>Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).</p>Formula:C15H10Cl2N2O2SPurity:96.57% - 99.23%Color and Shape:SolidMolecular weight:353.22Quinidine
CAS:<p>Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.</p>Formula:C20H24N2O2Purity:97.03% - 99.99%Color and Shape:Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)Molecular weight:324.42PYR-41
CAS:<p>PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.</p>Formula:C17H13N3O7Purity:98.25%Color and Shape:SolidMolecular weight:371.3Lupeol
CAS:<p>Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.</p>Formula:C30H50OPurity:98% - 99.96%Color and Shape:Needles From Alcohol Acetone White PowderMolecular weight:426.72Purvalanol A
CAS:<p>Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM for cdk2-cyclin A/B/E, and cdk4-cyclin D1, respectively.</p>Formula:C19H25ClN6OPurity:98.13% - 99.68%Color and Shape:PowderMolecular weight:388.89Meisoindigo
CAS:<p>Meisoindigo (Natura-α) is a derivative of indigo natural, might induces apoptosis and myeloid differentiation of acute myeloid leukemia (AML).</p>Formula:C17H12N2O2Purity:98.03% - 98.19%Color and Shape:SolidMolecular weight:276.29Pinosylvin
CAS:<p>Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.</p>Formula:C14H12O2Purity:99.89% - 99.91%Color and Shape:SolidMolecular weight:212.24M50054
CAS:<p>Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.</p>Formula:C13H16O4Purity:97.8%Color and Shape:SolidMolecular weight:236.26BI-847325
CAS:<p>BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.</p>Formula:C29H28N4O2Purity:97.13% - 97.54%Color and Shape:SolidMolecular weight:464.56BI 2536
CAS:<p>BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.</p>Formula:C28H39N7O3Purity:98% - 99.88%Color and Shape:SolidMolecular weight:521.65Copanlisib
CAS:<p>Copanlisib (BAY 80-6946), a PI3K inhibitor, may block tumor growth and improve cancer treatment efficacy.</p>Formula:C23H28N8O4Purity:99% - 99.88%Color and Shape:SolidMolecular weight:480.52Avicularin
CAS:<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Formula:C20H18O11Purity:97.02% - 99.94%Color and Shape:White PowderMolecular weight:434.35PD146176
CAS:<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Formula:C15H11NSPurity:98.00%Color and Shape:SolidMolecular weight:237.32Terrestrosin D
CAS:<p>Terrestrosin D triggers apoptosis, halts cell cycles, and blocks angiogenesis in tumor cells, displaying anti-cancer effects.</p>Formula:C50H80O23Purity:99.92% - 99.96%Color and Shape:SolidMolecular weight:1049.16Ganetespib
CAS:<p>Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.</p>Formula:C20H20N4O3Purity:98% - 99.95%Color and Shape:SolidMolecular weight:364.4Aminopurvalanol A
CAS:<p>Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1</p>Formula:C19H26ClN7OPurity:99.73%Color and Shape:SolidMolecular weight:403.91Apomine
CAS:<p>Apomine (SR-9223i) 是一种 HMG-CoA-还原酶抑制剂，可在体外促进骨髓瘤细胞的凋亡，并与体内骨髓瘤的调节有关。 Apomine 加速 3-羟基-3-甲基戊二酰-CoA 还原酶的降解并刺激低密度脂蛋白受体活性。 Apomine 通过下调 3-羟基-3-甲基戊二酰-CoA 还原酶来增强洛伐他汀对骨髓瘤细胞的抗肿瘤作用。</p>Formula:C28H52O7P2Purity:>99.99%Color and Shape:SolidMolecular weight:562.66TBHQ
CAS:<p>TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.</p>Formula:C10H14O2Purity:99.17% - 99.53%Color and Shape:White Solid PowderMolecular weight:166.22Ginsenoside Rh2
CAS:<p>Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.</p>Formula:C36H62O8Purity:99.20% - 99.76%Color and Shape:White PowderMolecular weight:622.87
