Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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Bromosporine
CAS:<p>Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.</p>Formula:C17H20N6O4SPurity:99.65% - 99.79%Color and Shape:SolidMolecular weight:404.44HO-3867
CAS:<p>HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor.</p>Formula:C28H30F2N2O2Purity:91.18% - 99.21%Color and Shape:SolidMolecular weight:464.55LRRK2-IN-1
CAS:<p>LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.</p>Formula:C31H38N8O3Purity:98% - 98.82%Color and Shape:SolidMolecular weight:570.69kauran-16,17-diol
CAS:<p>Kauran-16,17-diol, a natural diterpenoid product, exhibits anti-tumoral and apoptosis-inducing activities by inhibiting NO production in LPS-induced RAW 264.7</p>Formula:C20H34O2Purity:99.93%Color and Shape:SolidMolecular weight:306.48Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14S-trityl-L-Cysteine
CAS:<p>S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5</p>Formula:C22H21NO2SPurity:97.02%Color and Shape:Almost White To Light Yellow Granular PowderMolecular weight:363.47NSC 95397
CAS:<p>NSC 95397 is a potent inhibitor of Cdc25 dual specificity phosphatase(Ki of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively).</p>Formula:C14H14O4S2Purity:98.66%Color and Shape:SolidMolecular weight:310.39Diffractaic Acid
CAS:<p>Diffractaic Acid (NSC 685595) can inhibit LTB4 biosynthesis in A-23187-stimulated bovine PMNL cells with activity value of 8 μM.</p>Formula:C20H22O7Purity:99.81% - 99.87%Color and Shape:SolidMolecular weight:374.38SKI II
CAS:<p>SKI II is a selective non-ATP S1P receptor inhibitor with an IC50 of 0.5 μM; it doesn't inhibit PKCα, PI3K, or ERK2.</p>Formula:C15H11ClN2OSPurity:99.34% - 99.93%Color and Shape:SolidMolecular weight:302.78Prucalopride Succinate
CAS:<p>Prucalopride Succinate is a 5-HT4 receptor agonist with Ki 2.5 nM (5-HT4a) and 8 nM (5-HT4b).</p>Formula:C18H26ClN3O3·C4H6O4Purity:99.24%Color and Shape:SolidMolecular weight:485.96[6]-Gingerol
CAS:<p>[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for tumors.</p>Formula:C17H26O4Purity:98% - 99.66%Color and Shape:Light Yellow OilinessMolecular weight:294.39STF-118804
CAS:<p>STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.</p>Formula:C25H23N3O4SPurity:98.66%Color and Shape:SolidMolecular weight:461.53GSK1059615
CAS:<p>GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.</p>Formula:C18H11N3O2SPurity:99.3% - ≥95%Color and Shape:SolidMolecular weight:333.36Rabeprazole sodium
CAS:<p>Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.</p>Formula:C18H20N3NaO3SPurity:98% - 99.912%Color and Shape:White Or Off White Crystalline PowderMolecular weight:381.42Abacavir sulfate
CAS:<p>Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity</p>Formula:C14H18N6OH2O4SPurity:99.79% - 99.85%Color and Shape:White To Off-White SolidMolecular weight:335.38GMB-475
CAS:<p>GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.</p>Formula:C43H46F3N7O7SPurity:98.78% - >99.99%Color and Shape:SolidMolecular weight:861.93BMS-536924
CAS:<p>BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for</p>Formula:C25H26ClN5O3Purity:99.02%Color and Shape:SolidMolecular weight:479.962-Hydroxychalcone
CAS:<p>2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.</p>Formula:C15H12O2Purity:99.6%Color and Shape:SolidMolecular weight:224.25Pracinostat
CAS:<p>Pracinostat (SB939) is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in Clinicalal trials, allowing oral</p>Formula:C20H30N4O2Purity:99.15% - 99.67%Color and Shape:SolidMolecular weight:358.48Phellamurin
CAS:<p>Phellamurin blocks intestinal P-glycoprotein dose-dependently and it seriously interacts with cyclosporin; coadministration should be avoided.</p>Formula:C26H30O11Purity:97.91%Color and Shape:SolidMolecular weight:518.51Nelarabine
CAS:<p>Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.</p>Formula:C11H15N5O5Purity:98.10% - 99.6%Color and Shape:White SolidMolecular weight:297.27Astragalin
CAS:<p>Astragalin (Kaempferol 3-O-glucoside) is a biologically active natural flavonoid.</p>Formula:C21H20O11Purity:98.8% - ≥95%Color and Shape:SolidMolecular weight:448.38Dinaciclib
CAS:<p>Dinaciclib (SCH 727965) is a CDK inhibitor that selectively inhibits CDK1, CDK2, CDK5, and CDK9 (IC50 = 3/1/1/4 nM).</p>Formula:C21H28N6O2Purity:98.21% - 99.75%Color and Shape:SolidMolecular weight:396.49Buprofezin
CAS:<p>Buprofezin (Applaud) is an insecticide used for control of insect pests such as mealybugs, leafhoppers and whitefly on vegetable crops.</p>Formula:C16H23N3OSPurity:99.02% - 99.34%Color and Shape:White To Pale Yellow Crystalline PowderMolecular weight:305.44α-Hederin
CAS:<p>Alpha-Hederin (Tauroside E) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.</p>Formula:C41H66O12Purity:99.44% - 99.89%Color and Shape:SolidMolecular weight:750.96Propylparaben
CAS:<p>Propylparaben (Propyl parahydroxybenzoate) is an antimicrobial agent, preservative, flavouring agent</p>Formula:C10H12O3Purity:99.84%Color and Shape:White Solid CrystallineMolecular weight:180.20Etidronic acid
CAS:<p>Etidronic acid (HEDP) is a diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.</p>Formula:C2H8O7P2Purity:99.93% - ≥95%Color and Shape:Liquid SyrupMolecular weight:206.03Nafamostat mesylate
CAS:<p>Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis</p>Formula:C19H17N5O2·2CH4O3SPurity:97.36% - 99.76%Color and Shape:Tan To Pale Orange SolidMolecular weight:539.58KW-2449
CAS:<p>KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.</p>Formula:C20H20N4OPurity:98.43% - 99.69%Color and Shape:SolidMolecular weight:332.4WYC-209
CAS:<p>WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).</p>Formula:C20H20N2O3SPurity:99.77%Color and Shape:SolidMolecular weight:368.45Amentoflavone
CAS:<p>Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications.</p>Formula:C30H18O10Purity:98.21% - 99.22%Color and Shape:Odourless Whitish SolidMolecular weight:538.46Triptonide
CAS:<p>Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.</p>Formula:C20H22O6Purity:99.11% - 99.64%Color and Shape:White Crystalline PowderMolecular weight:358.39BAY 61-3606
CAS:<p>BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting</p>Formula:C20H18N6O3Purity:98.72%Color and Shape:SolidMolecular weight:390.4Niraparib hydrochloride
CAS:<p>Niraparib hydrochloride (MK-4827) is a PARP inhibitor with potential cancer treatment effects, causing DNA damage and apoptosis.</p>Formula:C19H21ClN4OPurity:99.26%Color and Shape:SolidMolecular weight:356.85PFI-90
CAS:<p>PFI-90, a selective histone demethylase (KDM3B) inhibitor, targets PAX3-FOXO1 action and demonstrates potential antitumor activity.</p>Formula:C11H10N4OPurity:99.46%Color and Shape:SolidMolecular weight:214.22AZD1208
CAS:<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Formula:C21H21N3O2SPurity:97.24% - 99.83%Color and Shape:SolidMolecular weight:379.48BAY 87-2243
CAS:<p>BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).</p>Formula:C26H26F3N7O2Purity:98% - 99.95%Color and Shape:SolidMolecular weight:525.53Quisinostat
CAS:<p>Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.</p>Formula:C21H26N6O2Purity:96.01% - ≥98%Color and Shape:SolidMolecular weight:394.47Niraparib tosylate monohyrate
CAS:<p>Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.</p>Formula:C26H30N4O5SPurity:97.7% - 98.41%Color and Shape:SolidMolecular weight:510.61D-Pantothenic acid hemicalcium salt
CAS:<p>D-Pantothenic acid hemicalcium salt (Calcium pantothenate), a kind of water soluble vitamin, can reduce the patulin content of the apple juice.</p>Formula:C9H17NO5CaPurity:98% - 99.89%Color and Shape:White Crystalline PowderMolecular weight:239.28Quiflapon sodium
CAS:<p>Quiflapon sodium (MK591) is a selective inhibitor of 5-Lipoxygenase-activating protein (FLAP).</p>Formula:C34H35ClN2NaO3SPurity:98%Color and Shape:SolidMolecular weight:610.16Sacubitril/Valsartan
CAS:<p>Sacubitril/Valsartan (LCZ696) is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for treatment of hypertension and heart failure.</p>Formula:C48H55N6O8Na3·5H2OPurity:99.75% - >99.99%Color and Shape:SolidMolecular weight:957.99SKI-178
CAS:<p>SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM.</p>Formula:C21H22N4O4Purity:97.09%Color and Shape:SolidMolecular weight:394.42Afatinib Dimaleate
CAS:<p>Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.</p>Formula:C32H33ClFN5O11Purity:98.11% - 99.87%Color and Shape:SolidMolecular weight:718.08Etretinate
CAS:<p>Etretinate (Ro 10-9359), an oral retinoid, treats psoriasis by promoting cell differentiation and reducing cell growth and inflammation.</p>Formula:C23H30O3Purity:97.89%Color and Shape:Crystals Crystalline SolidMolecular weight:354.48Sepantronium bromide
CAS:<p>Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.</p>Formula:C20H19BrN4O3Purity:99.68% - 99.85%Color and Shape:SolidMolecular weight:443.26Chelerythrine chloride
CAS:<p>Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to</p>Formula:C21H18ClNO4Purity:95% - 99.19%Color and Shape:Yellow To Orange SolidMolecular weight:383.83Cyasterone
CAS:<p>Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promising</p>Formula:C29H44O8Purity:99.32% - 99.70%Color and Shape:SolidMolecular weight:520.65Formosanin C
CAS:<p>Formosanin C (Polyphyllin B) is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity.</p>Formula:C51H82O20Purity:99.75% - >99.99%Color and Shape:SolidMolecular weight:1015.18
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