Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(127 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(91 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5618 products of "Apoptosis"
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HI5
CAS:<p>HI5: potent tubulin/IDO inhibitor, IC50 70 nM (HeLa), blocks kynurenine, G2/M arrest, spurs T cell activity, & triggers apoptosis.</p>Formula:C42H43N5O8Color and Shape:SolidMolecular weight:745.82Anticancer agent 55
CAS:<p>Potent anticancer agent inhibits cell growth, migration, induces apoptosis; promising for prostate, breast cancer studies.</p>Formula:C28H21Br2FN2O2Color and Shape:SolidMolecular weight:596.294Nevanimibe
CAS:<p>Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).</p>Formula:C27H39N3OPurity:98%Color and Shape:SolidMolecular weight:421.62PARP1-IN-10
CAS:<p>PARP1-IN-10 (12c) is a potent, non-toxic PARP1 inhibitor with a 50.62 nM IC50, enhancing TMZ effects and causing G2/M arrest and apoptosis.</p>Formula:C20H23N3O5Color and Shape:SolidMolecular weight:385.41MBC-11
CAS:<p>MBC-11: First bone-targeting bisphosphonate-etidronate conjugate with araC, may treat TIBD.</p>Formula:C11H20N3O14P3Purity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:511.21PDPOB
CAS:<p>PDPOB, a phenyl carboxylic acid derivative, may protect neurons from ischemic damage by reducing mitochondrial issues, oxidative stress, and cell death.</p>Formula:C15H20O5Color and Shape:SolidMolecular weight:280.32GLS1 Inhibitor-4
CAS:<p>GLS1 Inhibitor-4 (41e) has 11.86 nM IC50, strong binding, disrupts glutamine metabolism, induces apoptosis, and shows antitumor effects.</p>Formula:C29H27F3N10O2S2Purity:98%Color and Shape:SolidMolecular weight:668.72PD-1/PD-L1-IN-25
CAS:<p>"PD-1/PD-L1-IN-25 blocks PD-1/PD-L1 (IC50: 16.17 nM), boosting T-cell anti-tumor immunity, useful for cancer research."</p>Formula:C26H24ClN3O5Color and Shape:SolidMolecular weight:493.94GW837016X
CAS:<p>GW837016X, also known as NEU-391, is a potent inhibitor of protozoan parasite proliferation.</p>Formula:C25H20ClFN4OSColor and Shape:SolidMolecular weight:478.97Anti-inflammatory agent 47
CAS:<p>Flo8, an anti-inflammatory and antioxidant agent, effectively suppresses the release of reactive oxygen species (ROS) and nitric oxide (NO) while inhibiting</p>Formula:C25H18N2O3Purity:98%Color and Shape:SolidMolecular weight:394.42PHA-680626
CAS:<p>PHA-680626 is a PLK inhibitor, effective on resistant leukemia cells, with IC50: Plk1 (0.53 μM), Plk2 (0.07 μM), Plk3 (1.61 μM).</p>Formula:C23H26N6O2SColor and Shape:SolidMolecular weight:450.56LG308
CAS:<p>LG308, a synthetic compound, has anti-tumor properties, inducing apoptosis and mitotic arrest, thereby suppressing prostate cancer growth.</p>Formula:C19H17FN2OColor and Shape:SolidMolecular weight:308.35NF-κB-IN-5
CAS:<p>NF-κB-IN-5 (compound 4d) is an orally active NF-κB inhibitor.</p>Formula:C23H27N3O4Color and Shape:SolidMolecular weight:409.48Tubulin polymerization-IN-22
CAS:<p>Tubulin polymerization-IN-22 inhibits tubulin (IC50=8.1μM), blocks G2/M phase, and triggers apoptosis.</p>Formula:C19H16O4Color and Shape:SolidMolecular weight:308.33Ferroptosis inducer-1
CAS:<p>Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .</p>Formula:C25H21ClN2O5Color and Shape:SolidMolecular weight:464.9Antitumor agent-19
CAS:<p>Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.</p>Formula:C24H21ClF3N5OPurity:98.95% - 99.38%Color and Shape:SolidMolecular weight:487.9VEGFR-2-IN-23
CAS:<p>VEGFR-2-IN-23 (11b) is a potent VEGFR-2 inhibitor with an IC50 of 0.34 nM, exhibits antitumor effects, and causes G1 cell cycle arrest.</p>Formula:C22H15N5O2Color and Shape:SolidMolecular weight:381.39A-385358
CAS:A-385358 is a selective Bcl-xL inhibitor with Kis of 0.80 nM for Bcl-xL and 67 nM for Bcl-2, respectively.Formula:C32H41N5O5S2Purity:99.97%Color and Shape:SolidMolecular weight:639.83EGFR-IN-88
CAS:<p>EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosis</p>Formula:C22H18Cl2N4O2SPurity:98%Color and Shape:SolidMolecular weight:473.37FA16
<p>FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16</p>Formula:C22H27F3N4O2SPurity:99.44%Color and Shape:SolidMolecular weight:468.54NSC49652
CAS:<p>NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.</p>Formula:C14H11NO2Purity:98.98%Color and Shape:SolidMolecular weight:225.24p53-MDM2-IN-1
CAS:<p>p53-MDM2-IN-1 (Example 30), an inhibitor targeting the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 µM.</p>Formula:C23H20ClN3O3Purity:99.98%Color and Shape:SoildMolecular weight:421.88GSK854
CAS:<p>GSK854 is a selective TNNI3K inhibitor reducing heart damage and stress post-infarction in mice.</p>Formula:C18H19ClN6O4S2Purity:98.79%Color and Shape:SolidMolecular weight:482.96MMRi64
CAS:<p>MMRi64 inhibits Mdm2-MdmX, boosts p53, triggers apoptosis, and is used in cancer research.</p>Formula:C22H17Cl2N3OPurity:99.93%Color and Shape:SolidMolecular weight:410.3XX-650-23
CAS:<p>XX-650-23 is a CREB inhibitor that induces apoptosis and cell cycle arrest in AML cells and can be used to study acute myeloid leukemia (AML).</p>Formula:C18H12N2O2Purity:97.01%Color and Shape:SolidMolecular weight:288.3Necrostatin-5
CAS:<p>Necrostatin-5 (Nec-5) inhibits RIP1 kinase, prevents cell necrosis, and protects Fadd-deficient Jurkat cells with an EC50 of 240 nM.</p>Formula:C19H17N3O2S2Purity:98.03%Color and Shape:SolidMolecular weight:383.49CTA 056
CAS:<p>CTA 056 is an ITK inhibitor that inhibits the growth of MOLT-4 xenograft tumors in mice and can be used to study autoimmune disorders.</p>Formula:C35H34N6OPurity:97.22% - 97.76%Color and Shape:SolidMolecular weight:554.68Triciribine phosphate
CAS:<p>Triciribine phosphate (VD 002) is an AKT inhibitor that inhibits neovascularization and can be used in the study of leukemia.</p>Formula:C13H17N6O7PPurity:97.94%Color and Shape:SolidMolecular weight:400.28Brigimadlin
CAS:<p>Brigimadlin (BI 907828) is an orally active and highly potent antagonist of the E3 ubiquitin-protein ligase MDM2-p53 with antitumor activity.</p>Formula:C31H25Cl2FN4O3Purity:98.17%Color and Shape:SolidMolecular weight:591.46HS38
CAS:<p>HS38: DAPK-specific ATP-competitive inhibitor; Kds: DAPK1 (300 nM), PIM3 (200 nM), ZIPK (280 nM); useful in smooth muscle disorder research.</p>Formula:C14H12ClN5O2SPurity:98.19%Color and Shape:SolidMolecular weight:349.8UCB-5307
CAS:<p>UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.</p>Formula:C22H21N3OPurity:98.76%Color and Shape:SolidMolecular weight:343.42AOH1160
CAS:AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA).Formula:C25H20N2O3Purity:98.46% - 99.52%Color and Shape:SolidMolecular weight:396.44STAT3-IN-13
CAS:<p>STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.</p>Formula:C21H20N6O3SPurity:98.89%Color and Shape:SolidMolecular weight:436.49Cipepofol
CAS:HSK3486 is similar to propofol and is a general anesthetic, which may have therapeutic potential in insomnia, migraine, anxiety, analgesia, and other aspects.Formula:C14H20OPurity:99.77%Color and Shape:SolidMolecular weight:204.31TC-DAPK 6
CAS:<p>TC-DAPK 6 is an ATP-competitive inhibitor of Death-associated protein kinase (DAPK) with IC50s of 69 and 225 nM for DAPK1 and DAPK3.</p>Formula:C17H12N2O2Purity:98.73%Color and Shape:SolidMolecular weight:276.29iCRT-5
CAS:<p>iCRT-5 is a potent inhibitor of the Wnt pathway. iCRT-5 has antiproliferative activity and can be used in the study of multiple myeloma.</p>Formula:C16H17NO5S2Purity:99.68%Color and Shape:SolidMolecular weight:367.44SLMP53-1
CAS:<p>SLMP53-1 is a p53 activator with anti-tumor activity, activates reprogramming of glucose metabolism, and interferes with angiogenesis and migration</p>Formula:C20H18N2O2Purity:99.64%Color and Shape:SolidMolecular weight:318.37Alethine
CAS:<p>Alethine is a small antitumor compound used to treat cancers and infections, boosting T-cell cytotoxicity by raising TNFα.</p>Formula:C10H22N4O2S2Purity:98.83%Color and Shape:SolidMolecular weight:294.44N6-Cyclopentyladenosine
CAS:<p>N6-Cyclopentyladenosine (CPA) is a selective agonist of the adenosine A1 receptor and can be used to mimic the action of the adenosine A1 receptor, with Ki's of</p>Formula:C15H21N5O4Purity:99.84%Color and Shape:SolidMolecular weight:335.36Mepazine
CAS:<p>Mepazine, a MALT1 inhibitor, blocks GSTMALT1 (IC50: 0.83μM) and GSTMALT1 325-760 (IC50: 0.42μM), promoting apoptosis and reducing cell viability.</p>Formula:C19H22N2SPurity:99.88% - 99.92%Color and Shape:SolidMolecular weight:310.46LDCA
CAS:<p>LDCA inhibits LDH-A, disrupts mitochondrial function, induces apoptosis in cancer cells, and is non-toxic.</p>Formula:C8H5Cl3FNOPurity:98.99%Color and Shape:SolidMolecular weight:256.49LQZ-7F
CAS:LQZ-7F is a survivin dimerization inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation and inhibits human tumor growth.Formula:C14H7N9O3Purity:98.64%Color and Shape:SolidMolecular weight:349.26SB 699551 dihydrochloride
CAS:<p>SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.</p>Formula:C34H47Cl2N3OPurity:99.83%Color and Shape:SolidMolecular weight:584.66Vamotinib
CAS:<p>Vamotinib (PF-114) is a tyrosine kinase inhibitor with antiproliferative and antitumor activity.Vamotinib is used in the study of Alzheimer's disease.</p>Formula:C29H27F3N6OPurity:99.64%Color and Shape:SolidMolecular weight:532.56PARP/PI3K-IN-1
CAS:PARP/PI3K-IN-1 is a PARP and PI3K dual inhibitor with anticancer and antiproliferative activities for the study of breast, pancreatic and lung cancers.Formula:C33H28F4N8O3Purity:99.59%Color and Shape:SolidMolecular weight:660.62Pyrazoloacridine
CAS:<p>Pyrazoloacridine (PD 115934) binds DNA, inhibits topo I/II, has 1.25 μM IC50 in K562 cells, and exhibits anti-cancer effects.</p>Formula:C19H21N5O3Purity:99.72%Color and Shape:SolidMolecular weight:367.4DK419
CAS:<p>DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.</p>Formula:C16H8ClF6N3OPurity:99.63%Color and Shape:SolidMolecular weight:407.7Trk-IN-9
CAS:<p>Trk-IN-9 is a TRK inhibitor with anticancer and antiproliferative activity and can be used in cancer research.</p>Formula:C23H24ClFN6OPurity:98.15%Color and Shape:SolidMolecular weight:454.93Bomedemstat ditosylate
CAS:<p>Bomedemstat (IMG-7289) is an LSD1 inhibitor for acute myeloid leukemia, MDS, and Myelofibrosis; induces apoptosis by regulating p53, PUMA, and BCLXL.</p>Formula:C42H50FN7O8S2Purity:99.05%Color and Shape:SolidMolecular weight:864.02Ro24-7429
CAS:<p>Ro24-7429: oral HIV-1 Tat antagonist, RUNX1 inhibitor with anti-HIV, antifibrotic, and anti-inflammatory properties.</p>Formula:C14H13ClN4Purity:99.29% - 99.85%Color and Shape:SolidMolecular weight:272.73
