Caspase
Caspase inhibitors are compounds that block the activity of caspases, a family of proteases that are central executors of apoptosis. Caspases cleave specific substrates within the cell to trigger the apoptotic process, leading to programmed cell death. Caspase inhibitors are used to study the mechanisms of apoptosis, as well as to prevent unwanted cell death in various research models. These inhibitors are also explored in therapeutic contexts to protect cells from apoptosis in diseases such as neurodegeneration. At CymitQuimica, we offer a wide range of high-quality caspase inhibitors to support your research in apoptosis, cell death, and related fields.
Found 154 products of "Caspase"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Caspase-3 activator 2
Caspase-3 Activator 2 (Compound 2f) is a caspase 3 activator with cytotoxic effects on HL-60 and K562 cells, exhibiting IC 50 values of 33.52 μM and 76.90 μM,Purity:98%Color and Shape:Odour SolidAc-Trp-Glu-His-Asp-Aldehyde
CAS:Ac-Trp-Glu-His-Asp-Aldehyde is a powerful and selective inhibitor of caspase-1, demonstrating a K_i value of 56 pM [1] [2].Formula:C28H33N7O9Color and Shape:SolidMolecular weight:611.6IRF1-IN-2
CAS:IRF1-IN-2 is a small molecule IRF1 inhibitor that suppresses pyroptosis, protecting against radiation-induced skin damage.Formula:C18H20N2O4SPurity:99.85%Color and Shape:SolidMolecular weight:360.43Ac-AAVALLPAVLLALLAP-DEVD-CHO
CAS:Ac-AAVALLPAVLLALLAP-DEVD-CHO (DEVD-CHO-CPP 32) serves as a potent and reversible inhibitor of caspase-3 [1].Formula:C94H158N20O27Purity:98%Color and Shape:SolidMolecular weight:2000.38Reproxalap
CAS:Reproxalap (NS-2) is a dry eye treatment that neutralizes aldehydes like malondialdehyde.
Formula:C12H13ClN2OPurity:99.4% - 99.97%Color and Shape:SolidMolecular weight:236.7Ac-VDVAD-CHO TFA
Ac-VDVAD-CHO (TFA) is a caspase-2/3 inhibitor with IC50 values of 46 nM and 15 nM, respectively.Color and Shape:Odour SolidJ22352
CAS:J22352, a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC50 value of 4.7 nM, enhances anticancer effects inFormula:C24H21N3O4Color and Shape:SolidMolecular weight:415.44Almorexant hydrochloride
CAS:Almorexant hydrochloride (ACT 078573 hydrochloride) is a dual orexin receptor antagonist that induces apoptosis and can be used to study sleep disorders.Formula:C29H32ClF3N2O3Purity:99.85%Color and Shape:SolidMolecular weight:549.02MX1013
CAS:MX1013, a dipeptide pan-caspase inhibitor, inhibits caspase-1, -3, -6, -7, -8, and -9.Formula:C18H23FN2O6Color and Shape:SolidMolecular weight:382.39Tripeptide-32
CAS:Tripeptide-32 is a bioactive peptide recognized for its anti-aging properties, commonly utilized as an ingredient in cosmetics [1].Formula:C12H22N4O5Purity:98%Color and Shape:SolidMolecular weight:302.33Z-FA-FMK
CAS:Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.Formula:C21H23FN2O4Purity:98.84% - 99.68%Color and Shape:SolidMolecular weight:386.42Chelidonic acid
CAS:Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.Formula:C7H4O6Purity:99.03%Color and Shape:SolidMolecular weight:184.10Almorexant
CAS:Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.Formula:C29H31F3N2O3Purity:97.75% - 98.02%Color and Shape:SolidMolecular weight:512.56Asperosaponin VI
CAS:Asperosaponin VI, from Dipsacus asper rhizome, treats back pain, hematoma, and fractures.Formula:C47H76O18Purity:97.15% - 99.79%Color and Shape:SolidMolecular weight:929.10Z-IETD-FMK
CAS:Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.Formula:C30H43FN4O11Purity:95% - 99.81%Color and Shape:SolidMolecular weight:654.68Ginsenoside Rh2
CAS:Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.Formula:C36H62O8Purity:99.20% - 99.76%Color and Shape:White PowderMolecular weight:622.872-HBA
CAS:2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.Formula:C17H14O3Purity:99.76%Color and Shape:SolidMolecular weight:266.29Ref: TM-T7374
2mg34.00€5mg50.00€10mg75.00€25mg137.00€50mg213.00€100mg340.00€200mg504.00€1mL*10mM (DMSO)55.00€Ac-DEVD-AMC
CAS:Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .Formula:C30H37N5O13Purity:98.20%Color and Shape:White PowderMolecular weight:675.64KEA1-97
CAS:Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M).Formula:C15H9Cl2FN4Purity:97.07%Color and Shape:SolidMolecular weight:335.16Paris saponin VII
CAS:Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
Formula:C51H82O21Purity:99.51% - 99.63%Color and Shape:SolidMolecular weight:1031.18Z-VAD(OMe)-FMK
CAS:View and buy Z-VAD(OMe)-FMK from TargetMol.Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor.Cited in 10 publications.Formula:C22H30FN3O7Purity:95.92% - 99.71%Color and Shape:SolidMolecular weight:467.49Ref: TM-T6013
1mg57.00€2mg88.00€5mg144.00€10mg235.00€25mg349.00€50mg472.00€100mg658.00€200mg933.00€1mL*10mM (DMSO)145.00€PHYTOSPHINGOSINE
CAS:Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.Formula:C18H39NO3Purity:99.81%Color and Shape:SolidMolecular weight:317.51TC11
CAS:TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosisFormula:C20H22N2O2Purity:97.86%Color and Shape:SolidMolecular weight:322.4Belnacasan
CAS:Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.Formula:C24H33ClN4O6Purity:96.53% - 99.5%Color and Shape:SolidMolecular weight:508.99Ref: TM-T6090
2mg34.00€5mg52.00€10mg81.00€25mg161.00€50mg222.00€100mg396.00€200mg585.00€1mL*10mM (DMSO)52.00€Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14Ac-DEVD-pNA
CAS:Ac-DEVD-pNA is the preferred peptidic substrate for caspase-3.Formula:C26H34N6O13Purity:>99.99%Color and Shape:WhiteMolecular weight:638.58Ref: TM-T7816
2mg34.00€5mg57.00€10mg75.00€25mg160.00€50mg231.00€100mg335.00€200mg477.00€1mL*10mM (DMSO)79.00€Z-YVAD-FMK
CAS:AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.Formula:C31H39FN4O9Purity:98.00%Color and Shape:SolidMolecular weight:630.66Dihydrocapsaicin
CAS:Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.Formula:C18H29NO3Purity:99.8% - ≥95%Color and Shape:White CrystalMolecular weight:307.43Tauroursodeoxycholate
CAS:Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.Formula:C26H45NO6SPurity:98.77% - 99.93%Color and Shape:White SolidMolecular weight:499.7Diclofenac Potassium
CAS:Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.Formula:C14H10Cl2KNO2Purity:99.51%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:334.24CASP3 Activator 1541
CAS:CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.Formula:C24H17N3O4Purity:98.84%Color and Shape:SolidMolecular weight:411.41Ref: TM-T8652
1mg34.00€5mg71.00€10mg105.00€25mg215.00€50mg344.00€100mg532.00€200mg740.00€1mL*10mM (DMSO)86.00€5,7,4'-Trimethoxyflavone
CAS:5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.Formula:C18H16O5Purity:97.53%Color and Shape:SolidMolecular weight:312.32L67
CAS:L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).
Formula:C16H14Br2N4O4Purity:98.34% - 99.56%Color and Shape:SolidMolecular weight:486.11Phenoxodiol
CAS:Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP)Formula:C15H12O3Purity:98.07% - 99.18%Color and Shape:SolidMolecular weight:240.25Ref: TM-T16522
1mg63.00€5mg137.00€10mg215.00€25mg353.00€50mg537.00€100mg767.00€1mL*10mM (DMSO)150.00€Taurodeoxycholic acid sodium hydrate
CAS:Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.Formula:C26H46NNaO7SPurity:99.95%Color and Shape:SolidMolecular weight:539.70Ospemifene
CAS:Ospemifene (FC-1271a) is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA approved on February 26, 2013.Formula:C24H23ClO2Purity:99.95%Color and Shape:SolidMolecular weight:378.895,7-Dihydroxychromone
CAS:1.Formula:C9H6O4Purity:99.76% - ≥95%Color and Shape:SolidMolecular weight:178.14Ref: TM-T5S1805
1mg44.00€5mg84.00€10mg119.00€25mg197.00€50mg294.00€100mg437.00€500mg954.00€1mL*10mM (DMSO)75.00€Boc-Asp(OMe)-fluoromethyl ketone
CAS:Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.Formula:C11H18FNO5Purity:≥98%Color and Shape:SolidMolecular weight:263.26(E/Z)-Necrosulfonamide
CAS:(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.Formula:C18H15N5O6S2Purity:97.62% - 98%Color and Shape:SolidMolecular weight:461.47Lobaplatin
CAS:Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe.Formula:C9H18N2O3PtPurity:98.00%Color and Shape:SolidMolecular weight:397.33Z-DEVD-FMK
CAS:Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7,Formula:C30H41FN4O12Purity:96.19% - 99.69%Color and Shape:SolidMolecular weight:668.66Diethylnorspermine HBr
CAS:DENSPM is a potent polyamine analog that induces SSAT, arrests the cell cycle, and triggers apoptosis in various cancer cells.Formula:C13H36Br4N4Color and Shape:SolidMolecular weight:568.075Arnicolide D
CAS:Arnicolide D is a sesquiterpene lactone.Formula:C19H24O5Purity:96.66% - 99.93%Color and Shape:SolidMolecular weight:332.39EF24
CAS:EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.Formula:C19H15F2NOPurity:99.71%Color and Shape:SolidMolecular weight:311.33Ref: TM-T27242
1g1,510.00€1mg40.00€5mg85.00€10mg133.00€25mg235.00€50mg354.00€100mg533.00€500mg1,130.00€1mL*10mM (DMSO)93.00€PAC-1
CAS:PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.Formula:C23H28N4O2Purity:96.78% - 99.76%Color and Shape:SolidMolecular weight:392.49Ivachtin
CAS:Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining
Formula:C20H21N3O7SPurity:99.74%Color and Shape:SolidMolecular weight:447.46Penicillic acid
CAS:Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.
Formula:C8H10O4Purity:98%Color and Shape:Needles From Petroleum Ether Slight Yellow PowderMolecular weight:170.16Guggulsterone
CAS:Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.Formula:C21H28O2Purity:99.4% - 99.8%Color and Shape:Light Yellow PowderMolecular weight:312.45Ref: TM-T5574
1mg34.00€5mg50.00€10mg93.00€25mg152.00€50mg205.00€100mg289.00€200mg432.00€1mL*10mM (DMSO)55.00€Z-VAD-FMK
CAS:Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does notFormula:C21H28FN3O7Purity:98.24% - 99.79%Color and Shape:SolidMolecular weight:453.46Ref: TM-T7020
1mg112.00€5mg231.00€10mg394.00€25mg627.00€50mg890.00€100mg1,198.00€200mg1,603.00€1mL*10mM (DMSO)255.00€Tauroursodeoxycholate sodium
CAS:Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.Formula:C26H44NNaO6SPurity:97.90%Color and Shape:SolidMolecular weight:521.69
