Caspase
Caspase inhibitors are compounds that block the activity of caspases, a family of proteases that are central executors of apoptosis. Caspases cleave specific substrates within the cell to trigger the apoptotic process, leading to programmed cell death. Caspase inhibitors are used to study the mechanisms of apoptosis, as well as to prevent unwanted cell death in various research models. These inhibitors are also explored in therapeutic contexts to protect cells from apoptosis in diseases such as neurodegeneration. At CymitQuimica, we offer a wide range of high-quality caspase inhibitors to support your research in apoptosis, cell death, and related fields.
Found 125 products of "Caspase"
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Almorexant
CAS:<p>Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.</p>Formula:C29H31F3N2O3Purity:97.75% - 98.02%Color and Shape:SolidMolecular weight:512.56Asperosaponin VI
CAS:<p>Asperosaponin VI, from Dipsacus asper rhizome, treats back pain, hematoma, and fractures.</p>Formula:C47H76O18Purity:97.15% - 99.79%Color and Shape:SolidMolecular weight:929.1Z-IETD-FMK
CAS:<p>Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.</p>Formula:C30H43FN4O11Purity:95% - 99.81%Color and Shape:SolidMolecular weight:654.68Ginsenoside Rh2
CAS:<p>Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.</p>Formula:C36H62O8Purity:99.20% - 99.76%Color and Shape:White PowderMolecular weight:622.872-HBA
CAS:<p>2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.</p>Formula:C17H14O3Purity:99.76%Color and Shape:SolidMolecular weight:266.29Ac-DEVD-AMC
CAS:<p>Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .</p>Formula:C30H37N5O13Purity:98.20%Color and Shape:White PowderMolecular weight:675.64KEA1-97
CAS:<p>Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M).</p>Formula:C15H9Cl2FN4Purity:97.07%Color and Shape:SolidMolecular weight:335.16Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Formula:C51H82O21Purity:99.51% - 99.63%Color and Shape:SolidMolecular weight:1031.18Z-VAD(OMe)-FMK
CAS:<p>View and buy Z-VAD(OMe)-FMK from TargetMol.Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor.Cited in 10 publications.</p>Formula:C22H30FN3O7Purity:95.92% - 99.71%Color and Shape:SolidMolecular weight:467.49Ac-DEVD-CHO acetate
<p>Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.</p>Formula:C22H34N4O13Purity:98.54%Color and Shape:SolidMolecular weight:562.52PHYTOSPHINGOSINE
CAS:<p>Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.</p>Formula:C18H39NO3Purity:99.81%Color and Shape:SolidMolecular weight:317.51TC11
CAS:<p>TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis</p>Formula:C20H22N2O2Purity:97.86%Color and Shape:SolidMolecular weight:322.4Belnacasan
CAS:<p>Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.</p>Formula:C24H33ClN4O6Purity:96.53% - 99.5%Color and Shape:SolidMolecular weight:508.99Sesamolin
CAS:<p>Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.</p>Formula:C20H18O7Purity:98.77% - 99.04%Color and Shape:SolidMolecular weight:370.35Wedelolactone
CAS:<p>Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.</p>Formula:C16H10O7Purity:98.07% - 99.87%Color and Shape:SolidMolecular weight:314.25PI-1840
CAS:<p>PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.</p>Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.47Dehydrocorydaline
CAS:<p>1.</p>Formula:C22H24NO4Purity:99.84%Color and Shape:SolidMolecular weight:366.43Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14Ac-DEVD-pNA
CAS:<p>Ac-DEVD-pNA is the preferred peptidic substrate for caspase-3.</p>Formula:C26H34N6O13Purity:>99.99%Color and Shape:WhiteMolecular weight:638.58Z-YVAD-FMK
CAS:<p>AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.</p>Formula:C31H39FN4O9Purity:98.00%Color and Shape:SolidMolecular weight:630.66Emricasan
CAS:<p>Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties.</p>Formula:C26H27F4N3O7Purity:98.13% - 99%Color and Shape:SolidMolecular weight:569.5Z-FA-FMK
CAS:<p>Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.</p>Formula:C21H23FN2O4Purity:98.84% - 99.68%Color and Shape:SolidMolecular weight:386.42Dihydrocapsaicin
CAS:<p>Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.</p>Formula:C18H29NO3Purity:99.61% - ≥95%Color and Shape:White CrystalMolecular weight:307.43Aristolactam I
CAS:<p>Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway.</p>Formula:C17H11NO4Purity:98.98% - 99.63%Color and Shape:SolidMolecular weight:293.27Ossirene
CAS:<p>Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.</p>Formula:C2H4Cl3O2Te·H4NPurity:≥98%Color and Shape:SolidMolecular weight:312.05Tauroursodeoxycholate
CAS:<p>Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.</p>Formula:C26H45NO6SPurity:98.77% - 99.93%Color and Shape:White SolidMolecular weight:499.7Senkyunolide I
CAS:<p>1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.</p>Formula:C12H16O4Purity:99.73% - 99.88%Color and Shape:SolidMolecular weight:224.25Diclofenac Potassium
CAS:<p>Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.</p>Formula:C14H10Cl2KNO2Purity:99.51%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:334.24CASP3 Activator 1541
CAS:<p>CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.</p>Formula:C24H17N3O4Purity:98.84%Color and Shape:SolidMolecular weight:411.41L67
CAS:<p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>Formula:C16H14Br2N4O4Purity:98.34% - 99.56%Color and Shape:SolidMolecular weight:486.11Phenoxodiol
CAS:<p>Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP)</p>Formula:C15H12O3Purity:98.07%Color and Shape:SolidMolecular weight:240.25AVN-944
CAS:<p>AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.</p>Formula:C25H27N5O5Purity:99.07% - ≥95%Color and Shape:SolidMolecular weight:477.51Taurodeoxycholic acid sodium hydrate
CAS:<p>Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.</p>Formula:C26H46NNaO7SPurity:99.95%Color and Shape:SolidMolecular weight:539.705,7-Dihydroxychromone
CAS:<p>1.</p>Formula:C9H6O4Purity:99.76% - ≥95%Color and Shape:SolidMolecular weight:178.14Boc-Asp(OMe)-fluoromethyl ketone
CAS:<p>Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.</p>Formula:C11H18FNO5Purity:≥98%Color and Shape:SolidMolecular weight:263.26Tauroursodeoxycholate sodium
CAS:<p>Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.</p>Formula:C26H44NNaO6SPurity:97.90%Color and Shape:SolidMolecular weight:521.69Z-VAD-FMK
CAS:<p>Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does not</p>Formula:C21H28FN3O7Purity:98.24% - 99.79%Color and Shape:SolidMolecular weight:453.46(E/Z)-Necrosulfonamide
CAS:<p>(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.</p>Formula:C18H15N5O6S2Purity:97.62% - 98%Color and Shape:SolidMolecular weight:461.47Lobaplatin
CAS:<p>Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe.</p>Formula:C9H18N2O3PtPurity:98.00%Color and Shape:SolidMolecular weight:397.33Z-DEVD-FMK
CAS:<p>Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7,</p>Formula:C30H41FN4O12Purity:96.19% - 99.69%Color and Shape:SolidMolecular weight:668.66Arnicolide D
CAS:<p>Arnicolide D is a sesquiterpene lactone.</p>Formula:C19H24O5Purity:96.66%Color and Shape:SolidMolecular weight:332.39Dehydrocorydaline nitrate
CAS:<p>DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.</p>Formula:C22H24N2O7Purity:99.79% - 99.92%Color and Shape:SolidMolecular weight:428.44Dehydrotrametenolic acid
CAS:<p>Dehydrotrametenolic acid (Dehydroeburicoic acid) induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation in</p>Formula:C31H48O3Purity:98%Color and Shape:SolidMolecular weight:468.71Limonin glucoside
CAS:<p>Limonin glucoside: a citrus compound, blocks HIV/HTLV-1, triggers cancer cell death, kills Aedes larvae.</p>Formula:C32H42O14Color and Shape:SolidMolecular weight:650.674Caspase-3-IN-1
CAS:<p>Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).</p>Formula:C26H25N3O6SColor and Shape:SolidMolecular weight:507.56Tigilanol tiglate
CAS:<p>Tigilanol tiglate (EBC-46) is a PKC/C1 domain activator. Tigilanol tiglate induces immunogenic cell death and tumour regression.</p>Formula:C30H42O10Purity:98%Color and Shape:SolidMolecular weight:562.65Anisperimus
CAS:<p>Anisperimus (LF 15-0195) is an immunosuppressant that prevents CNS autoimmunity by promoting the development of regulatory CD4 T cells expressing Foxp3.</p>Formula:C18H39N7O3Purity:98.10%Color and Shape:SolidMolecular weight:401.55AD-2646
CAS:<p>AD-2646 has antidepressant activity and inhibits 2-deoxy-D-glucose (2-DG)-induced gastric acid secretion.</p>Formula:C23H40N2O4Color and Shape:SolidMolecular weight:408.57ZYZ-488
CAS:<p>ZYZ-488 is an Apoptosis protease activating factor-1 (Apaf-1) inhibitor, which suppresses the activation of procaspase-9 and procaspase-3.</p>Formula:C20H29N3O11Purity:99.04%Color and Shape:SolidMolecular weight:487.46Caspase-9 Inhibitor III
CAS:<p>Caspase-9 Inhibitor III (Ac-LEHD-cmk) blocks caspase-9, protects against ischemic heart damage.</p>Formula:C24H35ClN6O9Color and Shape:SolidMolecular weight:587.02
