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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3480 products of "Cell Cycle/Checkpoint"

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  • Palbociclib dihydrochloride


    <p>Palbociclib, oral CDK4/6 inhibitor (IC50: 11/16 nM), targets HR+/HER2- breast cancer and hepatocellular carcinoma.</p>
    Formula:C24H31Cl2N7O2
    Color and Shape:Solid
    Molecular weight:520.45
  • AT7519 TFA

    CAS:
    <p>AT7519 inhibits CDK1-6 kinases; IC50 ranges 0.018-0.66 μM.</p>
    Formula:C18H18Cl2F3N5O4
    Color and Shape:Solid
    Molecular weight:496.27
  • Palmatine

    CAS:
    <p>Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.</p>
    Formula:C21H22NO4
    Purity:96.28% - 99.49%
    Color and Shape:Solid
    Molecular weight:352.4
  • PF-06873600

    CAS:
    <p>PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.</p>
    Formula:C20H27F2N5O4S
    Purity:98.77% - 99.55%
    Color and Shape:Solid
    Molecular weight:471.52
  • 2'-Deoxy-2'-fluorocytidine

    CAS:
    <p>2'-Deoxy-2'-fluorocytidine is an nucleoside analog and inhibits of Crimean-Congo hemorrhagic fever virus (CCHFV) replication potently.</p>
    Formula:C9H12FN3O4
    Purity:99.90%
    Color and Shape:White Or Almost White Crystalline Powder
    Molecular weight:245.21
  • GLPG0187

    CAS:
    <p>GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).</p>
    Formula:C29H37N7O5S
    Purity:99.4% - 99.70%
    Color and Shape:Solid
    Molecular weight:595.71
  • Roniciclib

    CAS:
    <p>Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.</p>
    Formula:C18H21F3N4O3S
    Purity:98% - 98.63%
    Color and Shape:Solid
    Molecular weight:430.44
  • Tiazofurin

    CAS:
    <p>Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.</p>
    Formula:C9H12N2O5S
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:260.27
  • Apcin-A

    CAS:
    <p>Apcin-A is an anaphase-promoting complex (APC) inhibitor.</p>
    Formula:C10H14Cl3N5O2
    Color and Shape:Solid
    Molecular weight:342.61
  • SBC-115076

    CAS:
    <p>SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.</p>
    Formula:C31H33N3O5
    Purity:97.07% - 99.89%
    Color and Shape:Solid
    Molecular weight:527.61
  • TAK-632

    CAS:
    <p>TAK-632 is a potent pan-Raf inhibitor.</p>
    Formula:C27H18F4N4O3S
    Purity:98% - 99.5%
    Color and Shape:Solid
    Molecular weight:554.52
  • CAN508

    CAS:
    <p>CAN508: potent CDK9/T1 inhibitor; IC50 0.35 μM, Cdk2/E; Ki 13.3 μM, IC50 20 μM; 38x selective; antitumor.</p>
    Formula:C9H10N6O
    Purity:98.65%
    Color and Shape:Solid
    Molecular weight:218.22
  • GSK2850163 hydrochloride

    CAS:
    <p>GSK2850163 hydrochloride is a novel IRE1α inhibitor with IC50 of 20 nM for kinase and 200 nM for RNA enzyme.</p>
    Formula:C24H30Cl3N3O
    Color and Shape:Solid
    Molecular weight:482.87
  • CHR-6494 TFA

    CAS:
    <p>CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.</p>
    Formula:C18H17F3N6O2
    Purity:99.50%
    Color and Shape:Solid
    Molecular weight:406.36
  • Mitonafide

    CAS:
    <p>Mitonafide (NSC-300288) suppresses the activity of M. tuberculosis NAD+ dependent DNA ligase A. Mitonafide is a DNA intercalating agent.</p>
    Formula:C16H15N3O4
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:313.31
  • Ribociclib succinate hydrate

    CAS:
    <p>Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively).</p>
    Formula:C27H38N8O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:570.651
  • IMM-H007

    CAS:
    <p>IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression</p>
    Formula:C22H23N5O8
    Purity:97.73%
    Color and Shape:Solid
    Molecular weight:485.45
  • Phthalazinone pyrazole

    CAS:
    <p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>
    Formula:C18H15N5O
    Purity:97.03%
    Color and Shape:Solid
    Molecular weight:317.34
  • 2-Aminofluorene

    CAS:
    <p>2-Aminofluorene (2-Fluorenamine) is a biochemical.</p>
    Formula:C13H11N
    Purity:99.9%
    Color and Shape:Light Yellow Crystalline
    Molecular weight:181.23
  • PNU112455A hydrochloride

    CAS:
    <p>PNU112455A hydrochloride is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.</p>
    Formula:C10H12ClN5O2S
    Purity:98.58% - 99.22%
    Color and Shape:Solid
    Molecular weight:301.75
  • STAMBP-IN-1

    CAS:
    <p>STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release after</p>
    Formula:C27H28N4O4S
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:504.6
  • 5'-Deoxy-5-fluorocytidine

    CAS:
    <p>5'-Deoxy-5-fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine.</p>
    Formula:C9H12FN3O4
    Purity:99.67%
    Color and Shape:White Solid
    Molecular weight:245.21
  • Ibezapolstat

    CAS:
    <p>Ibezapolstat (ACX-362E) is an antibiotic with antibacterial activity that inhibits Clostridium difficile.</p>
    Formula:C18H20Cl2N6O2
    Purity:98% - 99.429%
    Color and Shape:Solid
    Molecular weight:423.3
  • RNase L-IN-2

    CAS:
    <p>RNase L-IN-2 activates RNase L at 22 uM, has antiviral effects on various RNA viruses, non-toxic at effective levels.</p>
    Formula:C16H14N2O2S
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:298.36
  • SCH900776

    CAS:
    <p>SCH900776 (MK-8776) is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.</p>
    Formula:C15H18BrN7
    Purity:96.69% - 99.6%
    Color and Shape:Solid
    Molecular weight:376.25
  • BMS-1166

    CAS:
    <p>BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.</p>
    Formula:C36H33ClN2O7
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:641.11
  • TH5427 hydrochloride

    CAS:
    <p>TH5427 HCl inhibits NUDT5 with 29 nM IC50; 690x more selective over MTH1; blocks ATP in breast cancer cells, hindering growth.</p>
    Formula:C20H21Cl3N8O3
    Color and Shape:Solid
    Molecular weight:527.79
  • TAK-960 hydrochloride

    CAS:
    <p>TAK-960 hydrochloride is an oral, potent PLK1 inhibitor with IC50 of 0.8 nM, effective against various tumor cells and xenografts.</p>
    Formula:C27H35ClF3N7O3
    Color and Shape:Solid
    Molecular weight:598.06
  • DMTr-LNA-5MeU-3-CED-phosphoramidite

    CAS:
    <p>DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.</p>
    Formula:C41H49N4O9P
    Purity:98.28%
    Color and Shape:Solid
    Molecular weight:772.82
  • FOY 251

    CAS:
    <p>FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.</p>
    Formula:C17H19N3O7S
    Purity:97.11% - 99.33%
    Color and Shape:Solid
    Molecular weight:409.41
  • SBC-110736

    CAS:
    <p>SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor</p>
    Formula:C26H27N3O2
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:413.51
  • SEL120-34A HCl

    CAS:
    <p>SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectively</p>
    Formula:C15H19Br2ClN4
    Purity:98.13% - 98.47%
    Color and Shape:Solid
    Molecular weight:450.6
  • FEN1-IN-SC13

    CAS:
    <p>FEN1-IN-SC13 is a potent inhibitor of DNA fragmentation endonuclease 1 (FEN1)</p>
    Formula:C24H23N3O3S
    Purity:98.02%
    Color and Shape:Solid
    Molecular weight:433.52
  • TAK-960 monohydrochloride

    CAS:
    <p>TAK-960 monohydrochloride, an oral compound, inhibits PLK1 (IC50=0.8 nM), PLK2, PLK3, stunts cancer cell growth, and is effective in tumor models.</p>
    Formula:C27H35ClF3N7O3
    Color and Shape:Solid
    Molecular weight:598.07
  • Amenamevir

    CAS:
    <p>Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mL</p>
    Formula:C24H26N4O5S
    Purity:99.00% - 99.86%
    Color and Shape:Solid
    Molecular weight:482.55
  • TH588 hydrochloride

    CAS:
    <p>TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.</p>
    Formula:C13H13Cl3N4
    Color and Shape:Solid
    Molecular weight:331.63
  • Garenoxacin mesylate hydrate

    CAS:
    <p>Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains</p>
    Formula:C23H20F2N2O4·CH4O3S·H2O
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:540.53
  • Nemorubicin

    CAS:
    <p>Nemorubicin (PNU 152243) is a unique doxorubicin variant with varied antitumor action, metabolism, and toxicity, effective against resistant tumors.</p>
    Formula:C32H37NO13
    Purity:97.4%
    Color and Shape:Solid
    Molecular weight:643.64
  • Methotrexate metabolite

    CAS:
    <p>DAMPA, active metabolite of Methotrexate, is a chemotherapeutic and immunosuppressive folic acid antagonist.</p>
    Formula:C15H15N7O2
    Purity:95.60% - 97.59%
    Color and Shape:Solid
    Molecular weight:325.33
  • Dalpiciclib

    CAS:
    <p>Dalpiciclib (SHR-6390) selectively inhibits CDK4/6 (IC50: 12.4/9.9 nM), is orally available, and impedes esophageal cancer growth.</p>
    Formula:C25H30N6O2
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:446.54
  • CYC-116

    CAS:
    <p>CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active</p>
    Formula:C18H20N6OS
    Purity:97.36% - 97.59%
    Color and Shape:Solid
    Molecular weight:368.46
  • PFM01

    CAS:
    <p>PFM01 inhibits MRE11 enzyme, steering DSBR towards NHEJ over HR.</p>
    Formula:C14H15NO2S2
    Purity:98.68%
    Color and Shape:Solid
    Molecular weight:293.4
  • Acelarin

    CAS:
    <p>Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.</p>
    Formula:C25H27F2N4O8P
    Purity:99.26%
    Color and Shape:Solid
    Molecular weight:580.47
  • Ocifisertib(CFI-400945 free base)

    CAS:
    <p>Ocifisertib (CFI-400945 free base) is a potent, selective and orally active inhibitor of polo-like kinase 4.Cost-effective and quality-assured.</p>
    Formula:C33H34N4O3
    Purity:98.53% - 99.04%
    Color and Shape:Solid
    Molecular weight:534.65
  • LJI308

    CAS:
    LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.
    Formula:C21H18F2N2O2
    Purity:99.73% - 99.87%
    Color and Shape:Solid
    Molecular weight:368.38
  • N1-Methylpseudouridine

    CAS:
    <p>N1-Methylpseudouridine (1-Methylpseudouridine) is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms by</p>
    Formula:C10H14N2O6
    Purity:98.95% - 99.88%
    Color and Shape:Solid
    Molecular weight:258.23
  • POL1-IN-1

    CAS:
    <p>POL1-IN-1 (Compound 3A) 是一种RNA 聚合酶 1 POL1抑制剂,IC50值低于 0.5 uM。 它能有效抑制A375恶性黑色素瘤细胞系中RNA 聚合酶I 的转录。</p>
    Formula:C21H20N6
    Purity:98% - 98.01%
    Color and Shape:Solid
    Molecular weight:356.42
  • Zoliflodacin

    CAS:
    <p>Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor.</p>
    Formula:C22H22FN5O7
    Purity:99.82% - 99.93%
    Color and Shape:Solid
    Molecular weight:487.44
  • HA-100

    CAS:
    <p>HA-100 is an inhibitor of protein kinase</p>
    Formula:C13H15N3O2S
    Purity:99.44%
    Color and Shape:Pale Yellow Crystalline Solid
    Molecular weight:277.34
  • LXW7

    CAS:
    <p>LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (</p>
    Formula:C29H48N12O12S2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:820.89
  • TCS7010

    CAS:
    <p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>
    Formula:C31H31ClFN7O2
    Purity:98.49% - 99.62%
    Color and Shape:Solid
    Molecular weight:588.07
  • MSC2530818

    CAS:
    <p>MSC2530818 is an effective, selective and orally available CDK8 inhibitor (IC50: 2.6 nM).</p>
    Formula:C18H17ClN4O
    Purity:98.93%
    Color and Shape:Solid
    Molecular weight:340.81
  • Fanotaprim

    CAS:
    <p>Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor.</p>
    Formula:C19H22N8O
    Purity:98.1%
    Color and Shape:Solid
    Molecular weight:378.43
  • MLN0905

    CAS:
    <p>MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM).</p>
    Formula:C24H25F3N6S
    Purity:97.17% - 98%
    Color and Shape:Solid
    Molecular weight:486.56
  • BMS-3

    CAS:
    <p>BMS-3 is a potent LIMK inhibitor with IC50s of 5 nM and 6 nM for LIMK1 and LIMK2, respectively.</p>
    Formula:C17H12Cl2F2N4OS
    Purity:99.31% - 99.81%
    Color and Shape:Solid
    Molecular weight:429.27
  • 6-O-Methyl Guanosine

    CAS:
    <p>6-O-Methyl Guanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line.</p>
    Formula:C11H15N5O5
    Purity:97.5%
    Color and Shape:Solid
    Molecular weight:297.27
  • EHT 1864 2HCl

    CAS:
    <p>EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.</p>
    Formula:C25H29Cl2F3N2O4S
    Purity:98.39% - 99.42%
    Color and Shape:Solid
    Molecular weight:581.47
  • kb-NB77-78

    CAS:
    <p>kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).</p>
    Formula:C18H25NO3Si
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:331.48
  • Talotrexin

    CAS:
    <p>Talotrexin (PT523), a nonpolyglutamatable antifolate analog of Aminopterin, inhibits DHFR and RFC, targeting tumor growth.</p>
    Formula:C27H27N9O6
    Color and Shape:Solid
    Molecular weight:573.56
  • 3-Deazauridine

    CAS:
    <p>3-Deazauridine (NSC-126849), a uridine analog, blocks CTP synthesis by competing with CTP synthetase.</p>
    Formula:C10H13NO6
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:243.21
  • Bonafton

    CAS:
    <p>Bonafton (Bonaphthone) is an antiviral agent.</p>
    Formula:C10H5BrO2
    Purity:97.16%
    Color and Shape:Solid
    Molecular weight:237.05
  • Ispinesib

    CAS:
    <p>Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic</p>
    Formula:C30H33ClN4O2
    Purity:98% - 99.09%
    Color and Shape:Solid
    Molecular weight:517.06
  • Saccharin 1-methylimidazole

    CAS:
    <p>Saccharin 1-methylimidazole (SMI) is a general-purpose activator used for DNA and RNA synthesis.</p>
    Formula:C7H5NO3S·C4H6N2
    Purity:98.21%
    Color and Shape:Solid
    Molecular weight:265.29
  • AZD-5597

    CAS:
    <p>AZD-5597 ((S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone) is a potent</p>
    Formula:C23H28FN7O
    Purity:98.01%
    Color and Shape:Solid
    Molecular weight:437.51
  • SP-146


    <p>SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).</p>
    Formula:C25H20FN7O
    Purity:97.82%
    Color and Shape:Solid
    Molecular weight:453.47
  • 3-AP

    CAS:
    <p>3-AP (Triapine) is a novel inhibitor of the M2 subunit of ribonucleotide reductase (RR).</p>
    Formula:C7H9N5S
    Purity:97.33% - 99.87%
    Color and Shape:Solid
    Molecular weight:195.24
  • DMT-2′Fluoro-dU Phosphoramidite

    CAS:
    <p>DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.</p>
    Formula:C39H46FN4O8P
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:748.78
  • ILK-IN-2

    CAS:
    <p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>
    Formula:C30H30F3N5O
    Purity:99.30%
    Color and Shape:Solid
    Molecular weight:533.59
  • GSK461364

    CAS:
    <p>GSK461364 (GSK461364A)(Ki=2.2 nM) inhibits purified Plk1 .The specificity of GSK461364 for Plk1 is more than 1000-fold over Plk2/3.</p>
    Formula:C27H28F3N5O2S
    Purity:99% - 99.73%
    Color and Shape:Solid
    Molecular weight:543.6
  • 2-Chloroadenosine

    CAS:
    <p>2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively</p>
    Formula:C10H12ClN5O4
    Purity:99.23%
    Color and Shape:White Powder
    Molecular weight:301.69
  • LY3405105

    CAS:
    <p>LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-</p>
    Formula:C26H39N7O3
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:497.63
  • UNC10217938A

    CAS:
    <p>UNC10217938A is a 3-deazapteridine analog, has strong oligonucleotide enhancing effects.</p>
    Formula:C26H28N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:456.54
  • Mps1-IN-1 dihydrochloride

    CAS:
    <p>Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM.</p>
    Formula:C28H35Cl2N5O4S
    Color and Shape:Solid
    Molecular weight:608.58
  • BMS-8

    CAS:
    <p>BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.</p>
    Formula:C27H28BrNO3
    Purity:98.88%
    Color and Shape:Solid
    Molecular weight:494.42
  • Brequinar

    CAS:
    <p>Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.</p>
    Formula:C23H15F2NO2
    Purity:99.1% - 99.57%
    Color and Shape:Solid
    Molecular weight:375.37
  • Pyridostatin hydrochloride

    CAS:
    <p>Pyridostatin hydrochloride stabilizes G-quadruplex DNA (Kd=490nM), inhibits cancer cell growth, and reduces SRC in breast cancer.</p>
    Formula:C31H37Cl5N8O5
    Color and Shape:Solid
    Molecular weight:778.94
  • PKD-IN-1 dihydrochloride (956121-30-5 free base)

    CAS:
    <p>CRT0066101 dihydrochloride is an inhibitor of PKD.</p>
    Formula:C18H21Cl3N4O
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:415.75
  • Brr2-IN-3

    CAS:
    <p>Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa.</p>
    Formula:C24H20N4O3S
    Purity:99.26%
    Color and Shape:Solid
    Molecular weight:444.51
  • RCM-1

    CAS:
    <p>RCM-1 is an inhibitor of FOXM1.</p>
    Formula:C20H12N2OS4
    Purity:98.08%
    Color and Shape:Solid
    Molecular weight:424.58
  • CCT 137690

    CAS:
    <p>CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).</p>
    Formula:C26H31BrN8O
    Purity:98.51% - 99.89%
    Color and Shape:Solid
    Molecular weight:551.48
  • Palmatine chloride

    CAS:
    <p>Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.</p>
    Formula:C21H22ClNO4
    Purity:97.9% - 99.47%
    Color and Shape:Solid
    Molecular weight:387.857
  • CHR-6494

    CAS:
    <p>CHR-6494 is a haspin inhibitor that inhibits histone H3T3 phosphorylation (IC50: 2 nM).</p>
    Formula:C16H16N6
    Purity:98.78%
    Color and Shape:Solid
    Molecular weight:292.34
  • Apcin

    CAS:
    <p>Apcin: potent APC/C(Cdc20) E3 ligase inhibitor, blocks substrate recognition &amp; mitosis, synergizes with Ts-Arg-OMe.</p>
    Formula:C13H14Cl3N7O4
    Purity:96.74%
    Color and Shape:Solid
    Molecular weight:438.65
  • S-trityl-L-Cysteine

    CAS:
    <p>S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5</p>
    Formula:C22H21NO2S
    Purity:97.02%
    Color and Shape:Almost White To Light Yellow Granular Powder
    Molecular weight:363.47
  • Orbofiban

    CAS:
    <p>Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.</p>
    Formula:C17H23N5O4
    Color and Shape:Solid
    Molecular weight:361.4
  • TH-263

    CAS:
    <p>TH-263 is inactive toward both LIMK1 and LIMK2 and thus can be used as negative control for TH-257, and is a diaryl sulfonamide derivative.</p>
    Formula:C21H20N2O3S
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:380.46
  • CKI-7 free base

    CAS:
    <p>CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.</p>
    Formula:C11H12ClN3O2S
    Color and Shape:Solid
    Molecular weight:285.75
  • Dasabuvir sodium

    CAS:
    <p>Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).</p>
    Formula:C26H26N3NaO5S
    Color and Shape:Solid
    Molecular weight:515.56
  • AT-9283 HCl

    CAS:
    <p>AT-9283, a multi-targeted kinase inhibitor, is used potentially for the treatment of multiple myeloma.</p>
    Formula:C19H24ClN7O2
    Color and Shape:Solid
    Molecular weight:417.89
  • 6-Chloropurine riboside

    CAS:
    <p>6-Chloropurine riboside (6-CPR): purine analog with antitumor, anti-inflammatory, antiviral, antifungal effects, and neuroprotective properties.</p>
    Formula:C10H11ClN4O4
    Purity:96.84%
    Color and Shape:Soild
    Molecular weight:286.6700
  • Peldesine dihydrochloride

    CAS:
    <p>Peldesine (BCX 34) dihydrochloride is an inhibitor of PNP in humans, rats, and mice, also hindering T-cell proliferation, used in lymphoma and HIV research.</p>
    Formula:C12H13Cl2N5O
    Color and Shape:Solid
    Molecular weight:314.17
  • Temozolomide Acid

    CAS:
    <p>TMZA, a TMZ metabolite, shows in vitro anticancer effects. TMZ, an oral alkylator, treats GBM and astrocytomas.</p>
    Formula:C6H5N5O3
    Purity:99.28%
    Color and Shape:Solid
    Molecular weight:195.14
  • CDK9-IN-30

    CAS:
    <p>CDK9-IN-30 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.</p>
    Formula:C16H20FNO3
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:293.33
  • 5-Chloro-2'-deoxyuridine

    CAS:
    <p>5-Chloro-2'-deoxyuridine (5-Chlorodeoxyuridine) is a thymine analog.</p>
    Formula:C9H11ClN2O5
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:262.65
  • EG1

    CAS:
    <p>EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.</p>
    Formula:C22H18N2O5
    Purity:97.48%
    Color and Shape:Solid
    Molecular weight:390.39
  • Dasabuvir

    CAS:
    <p>Dasabuvir (ABT-333) blocks HCV replication by inhibiting the essential NS5B RNA polymerase.</p>
    Formula:C26H27N3O5S
    Purity:99.54% - 99.62%
    Color and Shape:Solid
    Molecular weight:493.57
  • 1,4-Anthraquinone

    CAS:
    <p>1,4-Anthraquinone: anticancer, hinders nucleoside transport, inhibits synthesis, fragments DNA, curbs L1210 cell growth; aids HPLC analysis of NAC, CAP.</p>
    Formula:C14H8O2
    Purity:95.96% - 97.01%
    Color and Shape:Orange Brown Solid
    Molecular weight:208.21
  • Alovudine

    CAS:
    <p>3'-Fluoro-3'-deoxythymidine (3'-Deoxy-3'-fluorothymidine) is a marker of DNA synthesis,which is less susceptible to inflammatory changes than FDG.</p>
    Formula:C10H13FN2O4
    Purity:99.41%
    Color and Shape:Less Solid Colourless Solid
    Molecular weight:244.22
  • BAY-1816032

    CAS:
    <p>BAY-1816032 is a benzimidazole budding inhibition relieved homolog protein 1 kinase (BUB1) inhibitor.Cost-effective and quality-assured.</p>
    Formula:C27H24F2N6O4
    Purity:98.02% - 99.81%
    Color and Shape:Solid
    Molecular weight:534.51
  • Longdaysin

    CAS:
    <p>Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).</p>
    Formula:C16H16F3N5
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:335.33