Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(116 products)
- CDK(547 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(46 products)
- Dynamin(27 products)
- Ferroptosis(233 products)
- HSP(180 products)
- Integrin(276 products)
- Kinesin(87 products)
- LIM Kinase(21 products)
- Microtubule Associated(273 products)
- PKC(128 products)
- PLK(25 products)
- ROCK(61 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(77 products)
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Found 3935 products of "Cell Cycle/Checkpoint"
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Aurora Kinases-IN-3
CAS:Aurora Kinases-IN-3 is an oral AURKB inhibitor that disrupts its mitotic localization, not its H3 Ser10 phosphorylation.Formula:C20H16F3N3O4Color and Shape:SolidMolecular weight:419.35HBV-IN-22
CAS:HBV-IN-22 (Compound LC5f) is an HBV DNA replication inhibitor that acts on both wild-type HBV (IC50: 0.71 μM) and drug-resistant HBV (IC50: 0.84 μM).Formula:C26H29N3O2S2Color and Shape:SolidMolecular weight:479.66SRPIN-803
CAS:SRPIN-803 is a selective dual SRPK1 and CK2 inhibitor.Formula:C14H9F3N4O3SPurity:98%Color and Shape:SolidMolecular weight:370.31ROCK2-IN-5
ROCK2-IN-5, a compound blending fasudil, caffeic, and ferulic acids, shows promise for ALS research involving SOD1 mutations.Formula:C23H25N3O5SColor and Shape:SolidMolecular weight:455.53GSK317354A
CAS:GSK317354A is a GRK2 inhibitor.Formula:C25H18F4N6OColor and Shape:SolidMolecular weight:494.44BOP sodium
CAS:BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.Formula:C25H29N3NaO7SColor and Shape:SolidMolecular weight:538.57KIRA-7
CAS:KIRA-7: imidazopyrazine, anti-fibrotic, inhibits IRE1α RNase (IC50: 110 nM) allosterically.Formula:C27H23FN6OColor and Shape:SolidMolecular weight:466.51DNA Gyrase-IN-4
CAS:DNA Gyrase-IN-4 inhibits DNA cyclooxygenase (IC50: 0.13 μM) and is effective against Salmonella and E. coli.Formula:C22H15Cl2NO4SColor and Shape:SolidMolecular weight:460.33FUBP1-IN-2
CAS:FUBP1-IN-2 hinders FUBP1, affects c-Myc and p21 expression, and depletes polyamines.Formula:C26H26ClN3O4Color and Shape:SolidMolecular weight:479.96DHFR-IN-2
CAS:DHFR-IN-2 (4e) is a potent MtDHFR uncompetitive inhibitor with a 7 μM IC50, promising for TB research.Formula:C14H13NO2Color and Shape:SolidMolecular weight:227.26SR31527
CAS:SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.Formula:C15H14ClN3OSPurity:98.52%Color and Shape:SolidMolecular weight:319.81Ref: TM-T28848
1mg63.00€5mg137.00€1mL*10mM (DMSO)145.00€10mg215.00€25mg439.00€50mg708.00€100mg1,144.00€5,10-Dideazaaminopterin
CAS:5,10-Dideazaaminopterin is an antileukemic drug.Formula:C21H22N6O5Purity:98%Color and Shape:SolidMolecular weight:438.44HBV-IN-14
CAS:HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).Formula:C22H21ClN2O5Color and Shape:SolidMolecular weight:428.87MMV688845
CAS:MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.Formula:C24H25N3O3SColor and Shape:SolidMolecular weight:435.54RET-IN-19
CAS:RET-IN-19, a potent RET inhibitor, anticancer: IC50 6.8 nM (RET-wt), 13.51 nM (RET V804M); for NSCLC research.Formula:C28H28N6O4SColor and Shape:SolidMolecular weight:544.62(R)-Filanesib
CAS:(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).Formula:C20H22F2N4O2SColor and Shape:SolidMolecular weight:420.485-Ethynyluridine
CAS:5-Ethynyluridine marks new RNA for RICK, capturing proteins on various RNAs, even nonpolyadenylated types.Formula:C11H12N2O6Purity:99.78%Color and Shape:SolidMolecular weight:268.22Ref: TM-T36971
5mg49.00€1mL*10mM (DMSO)54.00€10mg84.00€25mg138.00€50mg236.00€100mg344.00€200mg515.00€Antibacterial agent 124
CAS:Antibacterial agent 124 inhibits Sa ProRS with an IC50 of 0.18 μM.Formula:C16H17ClFN3O2Color and Shape:SolidMolecular weight:337.78CDK9-IN-15
CAS:CDK9-IN-15: potent CDK9 inhibitor, blocks P-TEFb phosphorylation, inhibits transcription, reduces mRNA, induces tumor cell apoptosis.Formula:C16H11N3OSPurity:99.32%Color and Shape:SolidMolecular weight:293.34Ref: TM-T60619
1mL*10mM (DMSO)44.00€5mg46.00€10mg71.00€25mg126.00€50mg180.00€100mg260.00€200mg364.00€JA2131
CAS:JA2131: Small PARG inhibitor, IC50 0.4μM, induces DNA damage, stalls replication, kills cancer cells.Formula:C13H19N5O2S2Color and Shape:SolidMolecular weight:341.45Poloxipan
CAS:Poloxipan inhibits PLK1 (IC50: 3.2µM), PLK2 (1.7µM), PLK3 (3µM); minimal effect on Chk2, STAT1, STAT5b, Lck.Formula:C14H10BrN3O3SColor and Shape:SolidMolecular weight:380.22CTP Synthetase-IN-1
CAS:CTP Synthetase-IN-1 is a cytidine 5'-triphosphate synthetase (CTPS) inhibitor with antitumor activity for the study of arthritis and rheumatoid arthritis.Formula:C20H19F3N6O3S2Purity:98.11% - 99.18%Color and Shape:SolidMolecular weight:512.53Ref: TM-T72505
1mg65.00€5mg141.00€1mL*10mM (DMSO)158.00€10mg230.00€25mg477.00€50mg803.00€100mg1,378.00€RSK-IN-1
CAS:RSK-IN-1 (compound 7d) shows anti-tumor activity. RSK-IN-1 is an inhibitor of RSK that inhibits the phosphorylation of YB-1 [1].Formula:C22H17NO2Color and Shape:SolidMolecular weight:327.38CDK4/6-IN-8
CAS:CDK4/6-IN-8 (Compound 7p) is a selective inhibitor of CDK4 (IC50=5.01 nM) and CDK6 (IC50=3.97 nM).Formula:C18H18N6O5Color and Shape:SolidMolecular weight:398.37CDK8-IN-4
CAS:CDK8-IN-4 is an inhibitor of CDK8 (IC50: 0.2 nM).Formula:C20H18N4OColor and Shape:SolidMolecular weight:330.38IMB-10
CAS:IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.Formula:C19H15NOS2Color and Shape:SolidMolecular weight:337.46CDK12-IN-3
CAS:CDK12-IN-3 is a CDK12 inhibitor with anti-tumor activity and can be used for the study of malignant tumors.Formula:C23H28F2N8OPurity:99.85%Color and Shape:SolidMolecular weight:470.52Cdc7-IN-1
CAS:Cdc7-IN-1: selective ATP-competitive Cdc7 kinase inhibitor; IC50 0.6 nM at 1mM ATP; induces cancer cell death.Formula:C21H16ClN3O4Color and Shape:SolidMolecular weight:409.82CCG-257081
CAS:CCG-257081 blocks Rho/MRTF/SRF pathway; prevents fibrosis in mice; useful in cancer and fibrosis research.Formula:C24H19ClF3N3O2Purity:99.60% - 99.94%Color and Shape:SolidMolecular weight:473.87CLK1/2-IN-3
CAS:CLK1/2-IN-3 (Cpd-3) is a CLK1 and CLK2 inhibitor with antiproliferative activity that inhibits the activity of CLK and SRPK.Formula:C21H21N5O2Purity:99.04%Color and Shape:SolidMolecular weight:375.42CDK12-IN-E9
CAS:CDK12-IN-E9 is a potent and selective covalent CDK12 inhibitor and non-covalent CDK9 inhibitor while avoiding ABC transporter-mediated efflux.Formula:C24H30N6O2Color and Shape:SolidMolecular weight:434.53AS2863619 free base
CAS:AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells.Formula:C16H12N8OColor and Shape:SolidMolecular weight:332.32Centrinone-B
CAS:Centrinone-B (LCR-323) is a Plk4 inhibitor with potential anticancer activity for the study of triple-negative breast cancer.Formula:C27H27F2N7O5S2Purity:98.71%Color and Shape:SolidMolecular weight:631.67SP-471P
CAS:SP-471P inhibits DENV protease; EC50: DENV1-5.9 μM, DENV2-1.4 μM, DENV3-5.1 μM, DENV4-1.7 μM; CC50 >100 μM; lowers viral RNA synthesis.Formula:C33H26BrN5O2Color and Shape:SolidMolecular weight:604.5Crisnatol
CAS:Crisnatol (BWA770U) is an oral anticancer DNA intercalator, toxic to breast cancer cells, not skin fibroblasts.Formula:C23H23NO2Color and Shape:SolidMolecular weight:345.43L 888607 Racemate
CAS:L 888607 Racemate blocks DP1 and TP receptors with 132 nM and 17 nM affinity.Formula:C19H15ClFNO2SColor and Shape:SolidMolecular weight:375.84Ilorasertib hydrochloride
CAS:Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s:Formula:C25H22ClFN6O2SPurity:98.45%Color and Shape:SolidMolecular weight:525CLK1-IN-1
CAS:CLK1-IN-1 is a potent and selective inhibitor of the Cdc2-like kinase 1 (CLK1; IC50: 2 nM).Formula:C24H16FN5OColor and Shape:SolidMolecular weight:409.42Cdc7-IN-17
CAS:Cdc7-IN-17 is a potent inhibitor of CDC7 with an IC 50 of <10 μM that can be used in cancer research [1].Formula:C13H15N5OSColor and Shape:SolidMolecular weight:289.36THZ1-R
CAS:THZ1-R is a non-covalent active analogue of THZ1, with the acrylamide group removed from THZ1, not covalently bind to the C312 cysteine residue of CDK7.Formula:C31H30ClN7O2Purity:98%Color and Shape:SolidMolecular weight:568.07IXA6
CAS:IXA6 is an IRE1/XBP1s agonist with potential vasoprotective activity for the study of neurodegenerative diseases such as Parkinson's disease.Formula:C22H20ClN3O3SPurity:98.63%Color and Shape:SolidMolecular weight:441.9310-Formyl-5,8-dideazafolic acid
CAS:10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor.Formula:C22H21N5O7Purity:96.04%Color and Shape:SolidMolecular weight:467.43Tenofovir exalidex
CAS:Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistantFormula:C28H52N5O5PPurity:99.83%Color and Shape:SolidMolecular weight:569.72Kif15-IN-1
CAS:Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.Formula:C20H22N4O5SPurity:99.39% - 99.39%Color and Shape:SolidMolecular weight:430.48BPIC
CAS:BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.Formula:C27H20N2O5Color and Shape:SolidMolecular weight:452.46KIF18A-IN-3
CAS:KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.Formula:C28H38N4O5S2Purity:98.45%Color and Shape:SolidMolecular weight:574.763'-Deoxyuridine-5'-triphosphate
CAS:3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I & II, with a Ki of 2.0 µM.Formula:C9H15N2O14P3Color and Shape:SolidMolecular weight:468.14CDK8/19-IN-51
CAS:CDK8/19-IN-51 is a CDK8 and CDK19 inhibitor with anticancer activity, used in research on colorectal and gastric cancers.Formula:C23H22N6O2Purity:98.65% - 99.62%Color and Shape:SoildMolecular weight:414.46CDK8-IN-7
CAS:CDK8-IN-7 is a potent CDK8 inhibitor with a Kd of 3.5 nM, showing promise for AML research.Formula:C30H40N2Color and Shape:SolidMolecular weight:428.65XVA143
CAS:XVA143 is an integrin α/β I-like allosteric antagonist, inhibits LFA-1 (αLβ2 integrin)-dependent firm adhesion, induces extended conformations of integrins.Formula:C25H21Cl2N3O8Purity:99.94%Color and Shape:SolidMolecular weight:562.36HBV-IN-4
CAS:HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.Formula:C24H19ClFN5O3Color and Shape:SolidMolecular weight:479.89MLAF50
CAS:MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.Formula:C15H12I2O4Color and Shape:SolidMolecular weight:510.06Cdc7-IN-15
CAS:Cdc7-IN-15 (Example 108) is an inhibitor of cdc7 kinase that has potential to be used for cancer research [1].Formula:C12H14N4OSColor and Shape:SolidMolecular weight:262.33CP681301
CAS:CP681301 is a potent CDK5 inhibitor with anti-tumor effects in Drosophila and reduces Glioma stem cells' growth and renewal.Formula:C17H22N4OColor and Shape:SolidMolecular weight:298.38DNA Gyrase-IN-2
CAS:DNA Gyrase-IN-2 inhibits E. coli (IC50: 3.29-10.49 μM) and M. tuberculosis (IC50: 4.41-5.61 μM) COX, has antibacterial properties.Formula:C24H24N8OS2Color and Shape:SolidMolecular weight:504.63BMS-688521
CAS:BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.Formula:C26H19Cl2N5O4Purity:98.87%Color and Shape:SolidMolecular weight:536.37Ref: TM-T14676
1mg108.00€5mg264.00€1mL*10mM (DMSO)311.00€10mg371.00€25mg665.00€50mg874.00€100mg1,063.00€200mg1,423.00€CDK7-IN-15
CAS:CDK7-IN-15 (Compound 8) is an effective CDK7 inhibitor for studying cancers associated with transcriptional dysregulation.Formula:C21H24F4N6OSPurity:99.27%Color and Shape:SolidMolecular weight:484.51CLK1-IN-2
CLK1-IN-2: Metabolically stable, Clk1-selective inhibitor; IC50=1.7nM; useful in tumor, Duchenne MD, HIV-1, influenza research.Formula:C16H12Cl2N2O2SColor and Shape:SolidMolecular weight:367.25TDRL-X80
CAS:TDRL-X80 inhibits XPA DNA binding; effective on single, double, and cisplatin-damaged DNA; IC50: 18-29 μM (FP), 21-39 μM (ELISA).Formula:C23H15ClN2O6Color and Shape:SolidMolecular weight:450.83Laromustine
CAS:Laromustine (VNP40101M) is a sulfonyl hydrolysis alkylation prodrug for cancer treatment with significant anticancer activity, inhibiting thioredoxin reductase.Formula:C6H14ClN3O5S2Purity:≥98%Color and Shape:SolidMolecular weight:307.78Beaucage reagent
CAS:Beaucage reagent, which is found to be effective in causing DNA cleavage.Formula:C7H4O3S2Purity:98.50%Color and Shape:White To Off-White PowderMolecular weight:200.23CBL 0100 free base
CAS:CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.Formula:C24H26N2O2Purity:98.18% - 98.86%Color and Shape:SolidMolecular weight:374.48APC 366
CAS:APC 366: Mast cell tryptase inhibitor, Ki 7.1 μM. Reduces EAR, LAR, BHR in allergic asthma (sheep model).Formula:C22H28N6O4Purity:99.8%Color and Shape:SolidMolecular weight:440.5GW8510
CAS:GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.Formula:C21H15N5O3S2Purity:99.32%Color and Shape:SolidMolecular weight:449.51CH-1504
CAS:CH-1504, dihydrofolate reductase (DHFR) inhibitor, is used potentially for the treatment of rheumatoid arthritis.Formula:C23H23N5O5Color and Shape:SolidMolecular weight:449.46IDD388
CAS:IDD388 is a selective and potent aldose reductase (ALR2) inhibitor with antitumor activity that inhibits the ALR1 receptor.Formula:C16H12BrClFNO4Purity:99.56%Color and Shape:SolidMolecular weight:416.63MMV688844
CAS:MMV688844 inhibits M. abscessus DNA cyclooxygenase (IC50: 2μM) and has MIC50 of 12μM on strain bamboo; useful in antimicrobial studies.Formula:C23H25ClN4O2Color and Shape:SolidMolecular weight:424.92BPKDi
CAS:BPKDi is a potent and selective inhibitor of PKD (protein kinase D).Formula:C21H28N6OPurity:98%Color and Shape:SolidMolecular weight:380.49CDK7-IN-10
CAS:CDK7-IN-10: CDK7 inhibitor, IC50<100 nM, may hinder cell growth, induce apoptosis. (Patent WO2021016388A1, I-1)Formula:C29H35N7O3Color and Shape:SolidMolecular weight:529.63CDK7-IN-16
CAS:CDK7-IN-16, a potent CDK7 inhibitor (IC50: 1-10 nM), is used in cancer research with transcription defects.Formula:C19H21F3N6O2SColor and Shape:SolidMolecular weight:454.47DHX9-IN-1
CAS:DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].Formula:C21H21F2N5O3SColor and Shape:SolidMolecular weight:461.49Ref: TM-T82569
1mg205.00€5mg528.00€1mL*10mM (DMSO)537.00€10mg782.00€25mg1,161.00€50mg1,558.00€100mg2,322.00€Aloisine A
CAS:Aloisine A, a CDK/GSK-3 inhibitor with IC50: Cdk1/B-150nM, Cdk2/A-120nM, Cdk2/E-400nM, Cdk5/25-200nM, Cdk5/35-160nM, GSK-3α-500nM, GSK-3β-650nM, JNK-3-10μM.Formula:C16H17N3OPurity:98%Color and Shape:SolidMolecular weight:267.33TP1287
CAS:TP-1287 is an oral phosphate prodrug of the CDK9 inhibitor, alvocidib.Formula:C21H21ClNO8PColor and Shape:SolidMolecular weight:481.82WNK1-IN-1
CAS:WNK1-IN-1, a WNK1 inhibitor (IC50: 1.6 μM), also inhibits OSR1 phosphorylation (IC50: 4.3 μM), used in blood pressure and cancer research.Formula:C13H15BrCl2N2O4SPurity:98.09%Color and Shape:SolidMolecular weight:446.14Ref: TM-T73295
1mg71.00€5mg152.00€1mL*10mM (DMSO)167.00€10mg236.00€25mg485.00€50mg782.00€100mg1,305.00€DENV-IN-4
CAS:DENV-IN-4: Effective DENV inhibitor (EC50=4.79 μM), low toxicity (CC50>100 μM), and strong selectivity (SI>20.9); suppresses DENV2 and RdRp.Formula:C28H32N4O4SiColor and Shape:SolidMolecular weight:516.66Valategrast hydrochloride
CAS:Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.Formula:C30H33Cl4N3O4Purity:98%Color and Shape:SolidMolecular weight:641.41CDK9-IN-14
CAS:CDK9-IN-14: Potent CDK9 inhibitor, IC50=6.92 nM, effective on MV-4-11 cells and in vivo tumors, low toxicity, minimal side effects.Formula:C21H23F2N3O4Color and Shape:SolidMolecular weight:419.42Braco-19 trihydrochloride
CAS:BRACO19 3HCl inhibits telomerase, blocking its capping function, and prevents HAdV viral replication.Formula:C35H46Cl3N7O2Purity:98.74%Color and Shape:SolidMolecular weight:703.14FAK/aurora kinase-IN-1
CAS:FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].Formula:C23H24ClN7O3Color and Shape:SolidMolecular weight:481.93Synucleozid
CAS:Synucleozid is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.Formula:C22H20N6Purity:98%Color and Shape:SolidMolecular weight:368.43PF-4950834
CAS:PF-4950834, a ATP-competitive, selective Rho kinase inhibitor, provides therapeutic benefits in chronic inflammatory diseases.Formula:C21H19N3O2Purity:98%Color and Shape:SolidMolecular weight:345.39P18IN003
CAS:P18IN003 is a selective and effective p18(INK4C) inhibitor that inhibits the activity of p18 protein and can be used to study in vitro expansion ofFormula:C17H16N2O3Purity:99%Color and Shape:SolidMolecular weight:296.32PV-1115
CAS:PV-1115 is an effective and highly selective inhibitor of the Chk2.Formula:C20H19N7O3Purity:98%Color and Shape:SolidMolecular weight:405.41HIV-1 inhibitor-43
CAS:HIV-1 Inhibitor-43 suppresses HIV-1, with EC50: 21.3 nM (Y188L), 6.2 nM (K103N-Y181C), <0.7 nM (K103N/Y181C), and lowers HIV RNA/p24 protein.Formula:C24H21ClN2O4SColor and Shape:SolidMolecular weight:468.95Zelpolib
CAS:Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.Formula:C22H21N3O5S2Purity:98.79%Color and Shape:SolidMolecular weight:471.55(Rac)-Managlinat dialanetil
CAS:Managlinat dialanetil, an orally available and potent inhibitor of fructose 1,6-bisphosphatase (FBPase) used in research 2 type diabetes.Formula:C21H33N4O6PSPurity:98.52%Color and Shape:SolidMolecular weight:500.55DHODH-IN-12
CAS:DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.Formula:C10H9N3O2Purity:99.53%Color and Shape:SolidMolecular weight:203.2Ref: TM-T11021
1mg73.00€1mL*10mM (DMSO)122.00€5mg149.00€10mg213.00€25mg319.00€50mg447.00€100mg610.00€200mg823.00€CGP 53353
CAS:CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.Formula:C20H13F2N3O2Purity:98.11%Color and Shape:SolidMolecular weight:365.33JFN05510
CAS:Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.Formula:C50H68N7O9PSiColor and Shape:SolidMolecular weight:970.18Atuveciclib S-Enantiomer
CAS:Atuveciclib S-Enantiomer is a (S)-form of BAY-1143572; a potent, selective CDK9 inhibitor with an IC50 of 16 nM.Formula:C18H18FN5O2SPurity:98%Color and Shape:SolidMolecular weight:387.43Fosteabine
CAS:Fosteabine is an oral and prodrug analog of cytarabine. It is resistant to deoxycytidine deaminase.Formula:C27H50N3O8PPurity:98%Color and Shape:SolidMolecular weight:575.67DHODH-IN-24
CAS:DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].Formula:C26H26N4Color and Shape:SolidMolecular weight:394.51Aurora Kinases-IN-2
CAS:Aurora Kinases-IN-2 (12Aj) hinders Aurora A/B kinases (IC50: 90/152 nM), used in cancer studies.Formula:C22H18ClN5O3Color and Shape:SolidMolecular weight:435.86LSN 3213128
CAS:LSN 3213128: a potent oral antifolate targeting AICARFT with IC50s of 16 nM (enzyme) and 19 nM (cells), offers anti-tumor effects.Formula:C17H16FN3O4S2Color and Shape:SolidMolecular weight:409.45Myt1-IN-1
CAS:Myt1-IN-1 has anticancer effects that is a potent inhibitor of Myt1 with an IC 50 of <10 nM [1].Formula:C16H15ClN4O2Color and Shape:SolidMolecular weight:330.77Eg5 Inhibitor V, trans-24
CAS:Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.Formula:C26H21N3O3Purity:99.75%Color and Shape:SolidMolecular weight:423.46Ref: TM-T11155
1mg96.00€5mg193.00€1mL*10mM (DMSO)215.00€10mg289.00€25mg469.00€50mg642.00€100mg858.00€200mg1,153.00€AS-136A
CAS:AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.Formula:C17H19F3N4O3SPurity:98.52%Color and Shape:SolidMolecular weight:416.42Ref: TM-T62160
1mg215.00€5mg537.00€1mL*10mM (DMSO)590.00€10mg802.00€25mg1,369.00€50mg1,783.00€100mg2,395.00€CDK5 inhibitor 20-223
CAS:CDK5 inhibitor 20-223 is a potent CDK2/CDK5 inhibitor,anti-Colorectal Cancer (CRC), inhibiting cell migration and inducing cell cycle arrest.Formula:C19H19N3OColor and Shape:SolidMolecular weight:305.37AZD7762 HCl
CAS:AZD7762 HCl is a checkpoint kinase inhibitor, driving checkpoint abrogation and enhancing DNA-targeted treatment.Formula:C17H20ClFN4O2SPurity:98%Color and Shape:SolidMolecular weight:398.88VPC-70619
CAS:VPC-70619: Oral, selective N-Myc inhibitor; blocks cancer growth by hindering N-Myc-Max/DNA binding; well-absorbed.Formula:C16H8ClF3N4OColor and Shape:SolidMolecular weight:364.71
