Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(112 products)
- CDK(528 products)
- Cell Cycle Arrest(5 products)
- Chk(46 products)
- DYRK(49 products)
- Dynamin(27 products)
- Ferroptosis(226 products)
- HSP(179 products)
- Integrin(260 products)
- Kinesin(87 products)
- LIM Kinase(19 products)
- Microtubule Associated(283 products)
- PKC(111 products)
- PLK(25 products)
- ROCK(66 products)
- Rho(2 products)
- Wee1(14 products)
- c-Myc(77 products)
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Found 3768 products of "Cell Cycle/Checkpoint"
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Synucleozid hydrochloride
CAS:Synucleozid hydrochloride inhibits the translation of the intrinsically disordered protein α-synuclein by targeting its structured mRNA.Formula:C22H21ClN6Purity:98.13%Color and Shape:SolidMolecular weight:404.9N,N-Dimethyl-2'-O-methylcytidine
CAS:N,N-Dimethyl-2'-O-methylcytidine (N4, N4, 2'-O-Trimethylcytidine) is a purine nucleoside analogue with anti-cancer activity.Formula:C12H19N3O5Purity:99.62%Color and Shape:SolidMolecular weight:285.38-Chloroinosine
CAS:8-Chloroinosine is a purine nucleoside analog and a metabolite of the anticancer compound 8-chloro-adenosine.Formula:C10H11ClN4O5Purity:99.37% - 99.56%Color and Shape:SolidMolecular weight:302.67Kinesore
CAS:Kinesore is a cell-permeable modulator that binds to the microtubule motor protein kinesin-1, thereby inhibiting the interaction between KLC2 and SKIP.Formula:C20H16Br2N4O4Purity:97.24%Color and Shape:SolidMolecular weight:536.17Ref: TM-T15663
2mg42.00€5mg62.00€10mg87.00€25mg159.00€50mg230.00€100mg346.00€200mg520.00€1mL*10mM (DMSO)73.00€5'-O-DMT-N2-ibu-dG
CAS:5'-O-DMT-N2-ibu-dG is a deoxynucleoside served as a building block in oligonucleotide synthesis, with protecting groups to prevent unwanted reactions.Formula:C35H37N5O7Purity:98.71%Color and Shape:SolidMolecular weight:639.78-Bromoadenosine
CAS:8-Bromoadenosine is an adenosine derivative. 8-Br-Adenosine inhibitis mitochondrial membrane potential, cytoplasmic Ca²⁺ levels, and RNA and protein synthesis.Formula:C10H12BrN5O4Purity:99.11%Color and Shape:SolidMolecular weight:346.14NSC 23766
CAS:NSC 23766 is a Rac1 GTPase inhibitor by targeting GEFs, inhibiting cell proliferation.NSC23766 competitively inhibits M2 mAChR-induced Rac1 activation.Formula:C24H35N7Purity:99.49%Color and Shape:SolidMolecular weight:421.58N2-Isobutyryl-2-deoxyguanosine
CAS:<p>N2-Isobutyryl-2-deoxyguanosine（iBu-dG） is a nucleoside analog that can be used to synthesize oligonucleotides.</p>Formula:C14H19N5O5Purity:97.03%Color and Shape:SolidMolecular weight:337.33APE1-IN-1
CAS:APE1-IN-1 is a purine/pyrimidine-free endonuclease 1 inhibitor with potential antitumor activity that enhances the toxicity of alkylating agents on cancer cellsFormula:C19H21N3OS2Purity:98.5%Color and Shape:SolidMolecular weight:371.52PD 407824
CAS:PD 407824 is a chemical BMP sensitiser that promotes increased cellular sensitivity to subthreshold amounts of BMP4.PD 407824 is a potent inhibitor of the checkpoint kinases Chk1 and WEE1 (IC50s: 47 and 97 nM, respectively).Formula:C20H12N2O3Purity:98.02%Color and Shape:SolidMolecular weight:328.322'-O-Methyl-5-iodouridine
CAS:<p>2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a</p>Formula:C10H13IN2O6Purity:99.89%Color and Shape:SolidMolecular weight:384.12TG003
CAS:TG003 is a Clk1/Sty inhibitor that inhibits Clk1 and Clk4, suppresses cancer cell growth, and induces apoptosis.Formula:C13H15NO2SPurity:99.46%Color and Shape:SolidMolecular weight:249.33Ref: TM-T60367
1mg50.00€5mg97.00€10mg159.00€25mg281.00€50mg465.00€100mg558.00€200mg810.00€1mL*10mM (DMSO)170.00€A-674563 2HCl(552325-73-2(fb-2hcl))
A-674563 2HCl is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.Formula:C22H24Cl2N4OPurity:94.66%Color and Shape:SolidMolecular weight:431.36Ref: TM-T6139L
1mg86.00€5mg138.00€10mg188.00€25mg335.00€50mg505.00€100mg730.00€1mL*10mM (DMSO)170.00€Palbociclib
CAS:Palbociclib is an oral CDK4/6 inhibitor, halts Rb phosphorylation, arrests cell cycle, and curbs tumor growth.Formula:C24H29N7O2Purity:98% - 99.9%Color and Shape:SolidMolecular weight:447.53IMP-1088
CAS:IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.Formula:C25H29F2N5OPurity:98.48% - 99.52%Color and Shape:SolidMolecular weight:453.53Ref: TM-T9350
1mg144.00€2mg188.00€5mg283.00€10mg469.00€25mg833.00€50mg1,121.00€1mL*10mM (DMSO)310.00€BTYNB
CAS:BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1. MDK6620 downregulates β-TrCP1 mRNA and reduces activation of NF-κB.Formula:C12H9BrN2OSPurity:≥95%Color and Shape:SolidMolecular weight:309.186-Thio-2'-Deoxyguanosine
CAS:6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.Formula:C10H13N5O3SPurity:97.52%Color and Shape:SolidMolecular weight:283.31BUR1
CAS:BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.Formula:C16H17N5Purity:90%Color and Shape:SolidMolecular weight:279.34Trilaciclib
CAS:Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC₅₀ values of 1 nM and 4 nM respectively. enhances antitumour immunity.Formula:C24H30N8OPurity:99.624%Color and Shape:SolidMolecular weight:446.55SL327
CAS:SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier.Formula:C16H12F3N3SPurity:97.98% - >99.99%Color and Shape:SolidMolecular weight:335.35
