Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(541 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(48 products)
- Dynamin(27 products)
- Ferroptosis(226 products)
- HSP(180 products)
- Integrin(239 products)
- Kinesin(88 products)
- LIM Kinase(20 products)
- Microtubule Associated(275 products)
- PKC(117 products)
- PLK(25 products)
- ROCK(63 products)
- Rho(5 products)
- Wee1(14 products)
- c-Myc(76 products)
Show 10 more subcategories
Found 3827 products of "Cell Cycle/Checkpoint"
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Afuresertib
CAS:Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplasticFormula:C18H17Cl2FN4OSPurity:97.51% - 99.51%Color and Shape:SolidMolecular weight:427.32Ref: TM-T1911
1mg39.00€2mg50.00€5mg79.00€10mg97.00€25mg170.00€50mg274.00€100mg477.00€500mg1,035.00€1mL*10mM (DMSO)79.00€LY2334737
CAS:LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.Formula:C17H25F2N3O5Purity:98.82%Color and Shape:SolidMolecular weight:389.39Ref: TM-T4061
1mg38.00€5mg84.00€10mg117.00€25mg226.00€50mg338.00€100mg467.00€200mg615.00€1mL*10mM (DMSO)99.00€Levoleucovorin Calcium
CAS:Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.Formula:C20H21N7O7·CaPurity:99.07% - ≥98%Color and Shape:White Crystalline PowderMolecular weight:511.5SBC-115076
CAS:SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.Formula:C31H33N3O5Purity:97.07% - 99.89%Color and Shape:SolidMolecular weight:527.61Ref: TM-T2626
1mg38.00€2mg50.00€5mg80.00€10mg94.00€25mg172.00€50mg309.00€100mg477.00€500mg1,063.00€1mL*10mM (DMSO)87.00€Tegafur-Uracil
CAS:Tegafur-Uracil, an oral anticancer agent for solid tumor research, inhibits thymidylate synthase.Formula:C12H13FN4O5Color and Shape:SolidMolecular weight:312.257AT9283
CAS:AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).
Formula:C19H23N7O2Purity:99.83% - 99.98%Color and Shape:SolidMolecular weight:381.43GSK2850163 hydrochloride
CAS:GSK2850163 hydrochloride is a novel IRE1α inhibitor with IC50 of 20 nM for kinase and 200 nM for RNA enzyme.Formula:C24H30Cl3N3OColor and Shape:SolidMolecular weight:482.87GDC-0575
CAS:GDC-0575 (ARRY-575) is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).Formula:C16H20BrN5OPurity:≥95%Color and Shape:SolidMolecular weight:378.27Phthalazinone pyrazole
CAS:Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.Formula:C18H15N5OPurity:97.03%Color and Shape:SolidMolecular weight:317.34SL327
CAS:SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier.Formula:C16H12F3N3SPurity:97.98% - >99.99%Color and Shape:SolidMolecular weight:335.352-Aminofluorene
CAS:2-Aminofluorene (2-Fluorenamine) is a biochemical.Formula:C13H11NPurity:99.9%Color and Shape:Light Yellow CrystallineMolecular weight:181.236-Thio-2'-Deoxyguanosine
CAS:6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.Formula:C10H13N5O3SPurity:97.52%Color and Shape:SolidMolecular weight:283.31BTYNB
CAS:BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1. MDK6620 downregulates β-TrCP1 mRNA and reduces activation of NF-κB.Formula:C12H9BrN2OSPurity:≥95%Color and Shape:SolidMolecular weight:309.18STAMBP-IN-1
CAS:STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release afterFormula:C27H28N4O4SPurity:99.64%Color and Shape:SolidMolecular weight:504.6Ref: TM-T8706
1mg71.00€5mg160.00€10mg250.00€25mg535.00€50mg772.00€100mg1,074.00€1mL*10mM (DMSO)To inquireIMP-1088
CAS:IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.Formula:C25H29F2N5OPurity:98.48% - 99.52%Color and Shape:SolidMolecular weight:453.53Ref: TM-T9350
1mg144.00€2mg188.00€5mg283.00€10mg469.00€25mg833.00€50mg1,121.00€1mL*10mM (DMSO)310.00€RNase L-IN-2
CAS:RNase L-IN-2 activates RNase L at 22 uM, has antiviral effects on various RNA viruses, non-toxic at effective levels.Formula:C16H14N2O2SPurity:98.81%Color and Shape:SolidMolecular weight:298.36Ref: TM-T8591
1mg120.00€5mg264.00€10mg395.00€25mg627.00€50mg890.00€100mg1,198.00€200mg1,603.00€1mL*10mM (DMSO)243.00€MLS-573151
CAS:MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Formula:C21H19N3O2SPurity:98.80%Color and Shape:SolidMolecular weight:377.46Ref: TM-T22106
2mg34.00€5mg50.00€10mg86.00€25mg161.00€50mg245.00€100mg363.00€200mg515.00€1mL*10mM (DMSO)55.00€Palbociclib
CAS:Palbociclib is an oral CDK4/6 inhibitor, halts Rb phosphorylation, arrests cell cycle, and curbs tumor growth.Formula:C24H29N7O2Purity:98% - 99.9%Color and Shape:SolidMolecular weight:447.53A-674563 2HCl(552325-73-2(fb-2hcl))
A-674563 2HCl is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.Formula:C22H24Cl2N4OPurity:94.66%Color and Shape:SolidMolecular weight:431.36Ref: TM-T6139L
1mg86.00€5mg138.00€10mg188.00€25mg335.00€50mg505.00€100mg730.00€1mL*10mM (DMSO)170.00€TC-E 5003
CAS:TC-E 5003 (NSC-30176) is a selective inhibitor of PRMT1 with IC50 of 1.5 μM.Formula:C16H14Cl2N2O4SPurity:97.01%Color and Shape:SolidMolecular weight:401.26
