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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3486 products of "Cell Cycle/Checkpoint"

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  • Thymectacin
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    Thymectacin

    CAS:
    <p>Thymectacin (NB 1011) is a selective thymidine synthase (TS) inhibitor with anticancer activity for the study of colon cancer and solid tumors.</p>
    Formula:C21H25BrN3O9P
    Purity:97.05% - 99.49%
    Color and Shape:Solid
    Molecular weight:574.32

    Ref: TM-T24881

  • Cdk1/2 Inhibitor III
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    Cdk1/2 Inhibitor III

    CAS:
    <p>Cdk1/2 Inhibitor III is a selective Cdk1/2 inhibitor with an IC50 value of 2.1 μM against CDK1/cyclin B.</p>
    Formula:C15H13F2N7O2S2
    Purity:99.07%
    Color and Shape:Solid
    Molecular weight:425.44

    Ref: TM-T14914

  • αvβ1 integrin-IN-1
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    αvβ1 integrin-IN-1

    CAS:
    <p>αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.</p>
    Formula:C26H34N6O6S
    Purity:99.74% - >99.99%
    Color and Shape:Solid
    Molecular weight:558.65

    Ref: TM-T13473

  • AZD4573
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    AZD4573

    CAS:
    <p>AZD4573 is an effective and selective CDK9 inhibitor (IC50: &lt;4 nM). It enables transient target engagement for the treatment of hematologic malignancies.</p>
    Formula:C22H28ClN5O2
    Purity:99% - 99.51%
    Color and Shape:Solid
    Molecular weight:429.94

    Ref: TM-T10436

  • Debio-0123
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    Debio-0123

    CAS:
    Debio-0123: potent, specific oral WEE1 inhibitor; IC50 in low nanomolar; boosts DNA damage & Carboplatin's anti-cancer effects.
    Formula:C26H28Cl2N6O
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:511.45

    Ref: TM-T9864

  • CF53
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    CF53

    CAS:
    <p>CF53: potent, selective oral BET inhibitor; Ki &lt;1 nM, Kd 2.2 nM, IC50 2 nM for BRD4 BD1; high affinity for BRD2/3/4/BRDT; effective anti-tumor agent.</p>
    Formula:C24H25N7O2
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:443.5

    Ref: TM-T10773

  • CFI-402257
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    CFI-402257

    CAS:
    <p>CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.</p>
    Formula:C28H30N6O3
    Purity:96.66% - 99.51%
    Color and Shape:Solid
    Molecular weight:498.58

    Ref: TM-T22289

  • DHX9-IN-2
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    DHX9-IN-2

    CAS:
    <p>DHX9-IN-2 is an inhibitor targeting ATP-dependent RNA de-helicase A (DHX9) with anticancer and antitumor activity for cancer research.</p>
    Formula:C18H16ClN3O3S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:421.92

    Ref: TM-T82568

  • SMN-C3
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    SMN-C3

    CAS:
    <p>SMN-C3 (MV8T2MCK57) is an orally active modulator of SMN2 splicing, and has the potential to treat spinal muscular atrophy (SMA).</p>
    Formula:C24H28N6O
    Purity:99.01% - 99.05%
    Color and Shape:Solid
    Molecular weight:416.52

    Ref: TM-T12935

  • LY3295668
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    LY3295668

    CAS:
    <p>LY3295668 (AK-01) is a selective inhibitor of Aurora A with Kis of 0.8 nM and 1038 nM for Aurora A and B, respectively.</p>
    Formula:C24H26ClF2N5O2
    Purity:99.68%
    Color and Shape:Solid
    Molecular weight:489.95

    Ref: TM-T15815

  • BDP9066
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    BDP9066

    CAS:
    <p>BDP9066 is a potent and selective MRCK inhibitor, inhibits MRCKβ and MRCKα/β, and can be used for the prevention and treatment of skin cancer.</p>
    Formula:C20H24N6
    Purity:98.18%
    Color and Shape:Solid
    Molecular weight:348.44

    Ref: TM-T14521

  • Lomibuvir
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    Lomibuvir

    CAS:
    <p>Lomibuvir (VCH-222, VX-222) is an allosteric inhibitor of HCV NS5B with Kd 17 nM, blocks RNA elongation, EC50 5.2 nM for 1b/Con1.</p>
    Formula:C25H35NO4S
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:445.61

    Ref: TM-T6729

  • Sorivudine
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    Sorivudine

    CAS:
    <p>Sorivudine (BV-araU) is an antiviral blocking DNA synthesis in viruses like varicella, HSV-1, and Epstein-Barr.</p>
    Formula:C11H13BrN2O6
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:349.13

    Ref: TM-T16911

  • RNAP-σ interaction inhibitor-2
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    RNAP-σ interaction inhibitor-2

    CAS:
    <p>RNAP-σ interaction inhibitor-2 (compound 7d) is an inhibitor targeting the interaction between RNA polymerase and the sigma factor. It demonstrates inhibitory activity against S. aureus with a minimum inhibitory concentration (MIC) of 2 µg/mL.</p>
    Formula:C27H19Cl3N2O6S2
    Color and Shape:Solid
    Molecular weight:637.939

    Ref: TM-T206884

  • CDK2/4-IN-2
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    CDK2/4-IN-2

    CAS:
    <p>CDK2/4-IN-2 (compound 56) serves as a dual inhibitor for CDK2 and CDK4, exhibiting an IC50 of less than 100 nM. It is applicable in cancer research.</p>
    Formula:C18H20F3N7O3S2
    Color and Shape:Solid
    Molecular weight:503.52

    Ref: TM-T200624

  • Rhodblock 1a
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    Rhodblock 1a

    CAS:
    <p>Rhodblock 1a is an inhibitor of the Rho kinase signaling pathway, which disrupts the localization and function of proteins within the Rho pathway. This interference hinders the proper formation of the cleavage furrow during cell division, leading to some cells either failing to form the cleavage furrow or forming a ruptured furrow, resulting in binucleated cells. Rhodblock 1a can be utilized for investigating cell division mechanisms and holds potential for research into cardiovascular diseases and cancer.</p>
    Formula:C20H16N2O2
    Color and Shape:Solid
    Molecular weight:316.353

    Ref: TM-T206882

  • 2′-OMe-ADP
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    2′-OMe-ADP

    CAS:
    <p>2′-OMe-ADP is a nucleotide analogue used in oligonucleotide synthesis.</p>
    Formula:C11H17N5O10P2
    Color and Shape:Solid
    Molecular weight:441.23

    Ref: TM-TSW-00949

  • 7-Methylguanosine 5′-monophosphate
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    7-Methylguanosine 5′-monophosphate

    CAS:
    <p>7-Methylguanosine 5′-monophosphate (7-Methylguanylic acid) is a component of nucleic acids.</p>
    Formula:C11H16N5O8P
    Color and Shape:Solid
    Molecular weight:377.25

    Ref: TM-TSW-00951

  • PD-1-IN-17
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    PD-1-IN-17

    CAS:
    <p>PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM.</p>
    Formula:C13H22N6O7
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:374.35

    Ref: TM-T12377

  • GSK3335103
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    GSK3335103

    CAS:
    <p>GSK3335103 is a non-peptide, orally active inhibitor of αvβ6 integrin (pIC50=8), employed in the study of pulmonary fibrosis.</p>
    Formula:C27H36FN3O4
    Color and Shape:Solid
    Molecular weight:485.59

    Ref: TM-T200463