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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3477 products of "Cell Cycle/Checkpoint"

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  • 5'-DMTr-3'dA(Bz)-methylphosphonami dite


    <p>5’-DMTr-3’dA(Bz)-methylphosphonamidite, a purine nucleoside analog, exhibits wide-ranging antitumor activity, specifically targeting indolent lymphoid</p>
    Formula:C45H51N6O6P
    Color and Shape:Solid
    Molecular weight:802.9
  • N1-(2-Methyl)propyl pseudouridine


    <p>N1-(2-Methyl)propyl pseudouridine, a purine analog, targets lymphoid cancer by inhibiting DNA synthesis and inducing apoptosis.</p>
    Formula:C13H20N2O6
    Color and Shape:Solid
    Molecular weight:300.31
  • Psammaplin A

    CAS:
    <p>Psammaplin A: marine-derived, inhibits HDAC/DNA methyltransferases, strong DAC1 blocker (IC50=0.9nM), antimicrobial against Gram-positive bacteria, anticancer.</p>
    Formula:C22H24Br2N4O6S2
    Color and Shape:Solid
    Molecular weight:664.38
  • Ac-MRGDH-NH2


    <p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>
    Formula:C25H41N11O8S
    Color and Shape:Solid
    Molecular weight:655.727
  • Endo-1,4-β-xylanase

    CAS:
    <p>Endo-1,4-β-xylanase (CtXyn11A) is a type of xylan hydrolase that hydrolyzes the β-1,4-glycosidic bond of the xylan molecule.</p>
    Color and Shape:Solid
  • 5'(R)-C-Methyl-5-fluorouridine


    <p>5’(R)-C-Methyl-5-fluorouridine, a uridine analogue, possesses potential antiepileptic properties.</p>
    Formula:C10H13FN2O6
    Color and Shape:Solid
    Molecular weight:276.22
  • (S)-DI-87

    CAS:
    <p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor,reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>
    Formula:C23H30N6O3S2
    Purity:99.42%
    Color and Shape:Soild
    Molecular weight:502.65
  • Deoxythymidine-5'-triphosphate

    CAS:
    <p>Deoxythymidine-5'-triphosphate (dTTP) is a nucleoside triphosphate involved in DNA synthesis.</p>
    Formula:C10H17N2O14P3
    Color and Shape:Solid
    Molecular weight:482.167
  • Methylcarbamyl PAF C-8


    <p>Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.</p>
    Color and Shape:Odour Solid
  • PROTAC CDK9 degrader-8


    <p>PROTAC CDK9 Degrader-8 (Compound 21) is a potent degrader of CDK9 with an IC50 of 0.01 μM, utilized in cancer research [1].</p>
    Formula:C44H52Cl2N10O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:903.85
  • CDK1-IN-2

    CAS:
    <p>CDK1-IN-2 (cdk1 inhibitor 2) is a CDK1 inhibitor with IC50 of 5.8 μM.</p>
    Formula:C17H11ClN2O
    Purity:98.53%
    Color and Shape:Soild
    Molecular weight:294.73
  • Cytarabine triphosphate

    CAS:
    <p>Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.</p>
    Formula:C9H16N3O14P3
    Color and Shape:Solid
    Molecular weight:483.16
  • Aclacinomycin A

    CAS:
    <p>Aclacinomycin A has a wide range of applications in life science related research.</p>
    Formula:C42H53NO15
    Purity:99.43%
    Color and Shape:Solid
    Molecular weight:811.87
  • BLINK15


    <p>BLINK15 is a blood-brain barrier-permeable Cdk5 inhibitor. It reduces CDK5 activity in CDK5/p35 (IC50= 29.34 nM) and CDK5/p25 (IC50= 12.08 nM) complexes. Additionally, BLINK15 exhibits antidiabetic and neuroprotective effects. It lowers blood glucose levels in type 2 diabetes (T2D) mice, enhances cognitive abilities, and diminishes neurodegenerative lesions.</p>
    Color and Shape:Odour Solid
  • CDK2-IN-43


    <p>CDK2-IN-43 (Compound 3a) is a CDK2-cyclin E2 inhibitor with an IC50 value of 6.0 nM. It is applicable to cancer research.</p>
    Formula:C19H27N7O
    Color and Shape:Solid
    Molecular weight:369.464
  • ROCK-IN-32

    CAS:
    <p>ROCK-IN-32 is an effective Rho-kinase inhibitor.</p>
    Formula:C20H17Cl2N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:402.27
  • Ceftriaxone

    CAS:
    <p>Ceftriaxone: cephalosporin antibiotic, effective against Gram-positive/negative bacteria, with anti-inflammatory/antioxidant properties.</p>
    Formula:C18H18N8O7S3
    Purity:96.08%
    Color and Shape:Solid
    Molecular weight:554.58
  • Thailanstatin C

    CAS:
    <p>Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.</p>
    Formula:C30H46ClNO9
    Color and Shape:Solid
    Molecular weight:600.15
  • m7GpppUmpG

    CAS:
    <p>m7GpppUmpG, a trinucleotide cap analogue, enables RNA synthesis with cap 0 or 1 structures.</p>
    Formula:C31H42N12O26P4
    Color and Shape:Solid
    Molecular weight:1122.63
  • CCT241533 dihydrochloride

    CAS:
    <p>Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.</p>
    Formula:C23H29Cl2FN4O4
    Color and Shape:Solid
    Molecular weight:515.41