Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(95 products)
- CDK(501 products)
- Cell Cycle Arrest(4 products)
- Chk(42 products)
- DYRK(48 products)
- Dynamin(23 products)
- Ferroptosis(215 products)
- HSP(169 products)
- Integrin(224 products)
- Kinesin(66 products)
- LIM Kinase(19 products)
- Microtubule Associated(262 products)
- PKC(102 products)
- PLK(28 products)
- ROCK(69 products)
- Rho(2 products)
- Wee1(15 products)
- c-Myc(69 products)
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Found 3485 products of "Cell Cycle/Checkpoint"
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PD-1/PD-L1-IN-51
<p>PD-1/PD-L1-IN-51 (Compound III-4) is an inhibitor of PD-1/PD-L1 (IC50: hPD-L1 at 2.9 nM). It binds directly to PD-L1, blocking the interaction between PD-1 and PD-L1, and enhancing the release of IFN-γ. Additionally, PD-1/PD-L1-IN-51 exhibits antitumor activity.</p>Color and Shape:Odour SolidLB80317
CAS:<p>LB-80317, a DNA polymerase inhibitor, is used potentially for the potential treatment of hepatitis B virus infection.</p>Formula:C10H14N5O5PColor and Shape:SolidMolecular weight:315.22Ceftriaxone
CAS:<p>Ceftriaxone: cephalosporin antibiotic, effective against Gram-positive/negative bacteria, with anti-inflammatory/antioxidant properties.</p>Formula:C18H18N8O7S3Purity:96.08%Color and Shape:SolidMolecular weight:554.585'-O-Benzoyl-3'-O-(4-methoxybenzyl)-2'-O,4'-C-methyleneuridine
<p>5’-O-Benzoyl-3’-O-(4-methoxybenzyl)-2’-O,4’-C-methyleneuridine is a purine nucleoside analog with broad antitumor activity, primarily targeting indolent</p>Formula:C25H24N2O8Color and Shape:SolidMolecular weight:480.47Orbofiban acetate
CAS:<p>Orbofiban Acetate is a compound that serves as an antagonist to the platelet GPIIb/IIIa receptor, effectively inhibiting platelet aggregation when administered</p>Formula:C19H27N5O6Color and Shape:SolidMolecular weight:421.452'-OMe-Ac-C Phosphoramidite
CAS:<p>2'-OMe-Ac-C Phosphoramidite, a modified phosphoramidite, is utilized in the synthesis of oligonucleotides.</p>Formula:C42H52N5O9PColor and Shape:SolidMolecular weight:801.86LXY3
CAS:<p>LXY3 (LXY2) is a VLA-3 blocking peptide that inhibits the interaction of neutrophil surface integrin α3β1 (VLA-3) with laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is employed to block the neutrophil-mediated release of nanoparticles from the perivascular pool into the tumor stroma and is frequently used for targeted imaging in breast cancer.</p>Formula:C32H43N11O15S2Color and Shape:SolidMolecular weight:885.88CCT241533 dihydrochloride
CAS:<p>Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.</p>Formula:C23H29Cl2FN4O4Color and Shape:SolidMolecular weight:515.41m7GpppGpG
CAS:<p>m7GpppGpG, a trinucleotide cap, protects mRNA from 5′ exonucleases & aids splicing and translation.</p>Formula:C31H41N15O25P4Color and Shape:SolidMolecular weight:1147.642'-O-Methyladenosine 5'-monophosphate triethyl ammonium
<p>2’-O-Methyladenosine 5’-monophosphate triethyl ammonium is an adenosine analog.</p>Formula:C11H14N5O7P2Color and Shape:SolidMolecular weight:359.23Ribonuclease T1
CAS:<p>Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.</p>Color and Shape:SolidGS-443902 trisodium
CAS:<p>GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.</p>Formula:C12H16N5O13P3·xNaColor and Shape:SolidDNA Gyrase-IN-12
<p>DNA Gyrase-IN-12 (Compound 6d) is an inhibitor of DNA gyrase. It exhibits antibacterial activity with MIC values ranging from 0.031 to 0.0625 μg/mL against Vancomycin-Intermediate Staphylococcus aureus (VISA) and Enterococcus faecium.</p>Color and Shape:Odour SolidCDK7-IN-2 hydrochloride hydrate
CAS:<p>CDK7-IN-2 HCl hydrate is a potent, specific CDK7 enzyme inhibitor with significant anti-cancer effects.</p>Formula:C26H42ClN7O4Color and Shape:SolidMolecular weight:552.12Apcin A HCL
CAS:<p>Apcin A HCL is an Apcin-derived APC inhibitor that binds Cdc20 and hinders ubiquitination, useful for synthesizing PROTAC CP5V.</p>Formula:C10H15Cl4N5O2Purity:99.59%Color and Shape:SolidMolecular weight:379.07N4-Benzoyl-2'-deoxy-2'-fluoro-β-D-arabinocytidine
<p>N4-Benzoyl-2’-deoxy-2’-fluoro-β-D-arabinocytidine, a purine nucleoside analog, exhibits widespread antitumor activity, particularly against indolent lymphoid</p>Formula:C16H16FN3O5Color and Shape:SolidMolecular weight:349.318-Chloro-2'-deoxy-2'-fluoro-arabino adenosine
<p>8-Chloro-2’-deoxy-2’-fluoro-arabino adenosine, a purine nucleoside analog, demonstrates broad antitumor activity against indolent lymphoid malignancies.</p>Formula:C10H11ClFN5O3Color and Shape:SolidMolecular weight:303.68TFMU-ADPr triethylamine
<p>TFMU-ADPr triethylamine is a substrate for PARG activity measurement, releasing a fluorophore to indicate PAR hydrolase activity.</p>Formula:C25H26F3N5O16P2·5C6H15NColor and Shape:SolidMolecular weight:1024.42IRE1-IN-2
<p>IRE1-IN-2 (compound G15) functions as a potent inhibitor of IRE1. It effectively suppresses lipid accumulation induced by FFA, exhibiting an IC50 value of 2.06 μM.</p>Formula:C16H20O6Color and Shape:SolidMolecular weight:308.12599huATN-658
<p>huATN-658 (MNPR-101) is a humanized monoclonal antibody inhibitor targeting the urokinase-type plasminogen activator receptor (uPAR). It effectively disrupts the interaction between uPAR and integrins, thereby inhibiting tumor cell proliferation, invasion, and migration. huATN-658 shows potential for research in breast cancer, particularly in cases of triple-negative breast cancer.</p>Color and Shape:Odour Liquid
