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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3477 products of "Cell Cycle/Checkpoint"

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  • Orbofiban acetate
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    Orbofiban acetate

    CAS:
    <p>Orbofiban Acetate is a compound that serves as an antagonist to the platelet GPIIb/IIIa receptor, effectively inhibiting platelet aggregation when administered</p>
    Formula:C19H27N5O6
    Color and Shape:Solid
    Molecular weight:421.45

    Ref: TM-T73643

  • 2'-OMe-Ac-C Phosphoramidite
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    2'-OMe-Ac-C Phosphoramidite

    CAS:
    <p>2'-OMe-Ac-C Phosphoramidite, a modified phosphoramidite, is utilized in the synthesis of oligonucleotides.</p>
    Formula:C42H52N5O9P
    Color and Shape:Solid
    Molecular weight:801.86

    Ref: TM-T75265

  • JH-XVI-178
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    JH-XVI-178

    CAS:
    <p>JH-XVI-178: potent CDK8/19 inhibitor with good pharmacokinetics, low clearance, moderate oral bioavailability.</p>
    Formula:C22H22ClN7O
    Color and Shape:Solid
    Molecular weight:435.92

    Ref: TM-T40280

  • T-2513
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    T-2513

    CAS:
    <p>T-2513 inhibits topoisomerase I by covalently bonding to its DNA complex, blocking DNA replication and causing cell death.</p>
    Formula:C25H27N3O5
    Color and Shape:Solid
    Molecular weight:449.507

    Ref: TM-T40365

  • 5'-O-DMT-rI
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    5'-O-DMT-rI

    CAS:
    <p>5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].</p>
    Formula:C31H30N4O7
    Color and Shape:Solid
    Molecular weight:570.59

    Ref: TM-T37140

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    6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

    <p>6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, boasts a broad spectrum of biochemical and</p>
    Formula:C10H17N7O3
    Color and Shape:Solid
    Molecular weight:283.29

    Ref: TM-T75187

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    STX-100

    <p>PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.</p>
    Purity:97.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.3% (SDS-PAGE); 97.5% (SEC-HPLC)
    Color and Shape:Odour Liquid

    Ref: TM-T9901A-062

  • Py-MAA-Val-Cit-PAB-DX8951
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    Py-MAA-Val-Cit-PAB-DX8951

    CAS:
    <p>Py-MAA-Val-Cit-PAB-DX8951, a purine toxin, serves as an intermediate in the synthesis of antibody-drug conjugates [1].</p>
    Formula:C57H66FN11O13S
    Color and Shape:Solid
    Molecular weight:1164.26

    Ref: TM-T75117

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    PP-C8

    <p>PP-C8: PROTAC CDK12-Cyclin K degrader with DC50s 416/412 nM; synergizes with PARP inhibitor against TNBC.</p>
    Formula:C43H51FN12O7
    Color and Shape:Solid
    Molecular weight:866.94

    Ref: TM-T74359

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    1-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine

    <p>1-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine is an adenosine analog.</p>
    Formula:C18H18F3N5O4
    Color and Shape:Solid
    Molecular weight:425.36

    Ref: TM-T75042

  • CDK12-IN-6
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    CDK12-IN-6

    CAS:
    <p>CDK12-IN-6, a pyrazolotriazine, strongly inhibits CDK12 (IC50 1.19 μM at 2 mM ATP), but not CDK2/Cyclin E or CDK9/Cyclin T1 (both IC50 &gt;20 μM).</p>
    Formula:C20H21F2N9
    Color and Shape:Solid
    Molecular weight:425.448

    Ref: TM-T40289

  • LXY3
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    LXY3

    CAS:
    <p>LXY3 (LXY2) is a VLA-3 blocking peptide that inhibits the interaction of neutrophil surface integrin α3β1 (VLA-3) with laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is employed to block the neutrophil-mediated release of nanoparticles from the perivascular pool into the tumor stroma and is frequently used for targeted imaging in breast cancer.</p>
    Formula:C32H43N11O15S2
    Color and Shape:Solid
    Molecular weight:885.88

    Ref: TM-TP3270

  • Heliquinomycin
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    Heliquinomycin

    CAS:
    <p>Heliquinomycin, a Streptomyces metabolite, inhibits DNA helicase (Ki=6.8 μM) and fights Gram-positive bacteria and various cancer cells.</p>
    Formula:C33H30O17
    Color and Shape:Solid
    Molecular weight:698.586

    Ref: TM-T36748

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    5'-O-DMTr-2'-O-MOE inosine 3'-P-methyl phosphonamidite

    <p>5’-O-DMTr-2’-O-MOE inosine 3’-P-methyl phosphonamidite, a purine nucleoside analog, exhibits extensive antitumor activity specific to indolent lymphoid</p>
    Formula:C41H52N5O8P
    Color and Shape:Solid
    Molecular weight:773.85

    Ref: TM-T75229

  • (1S,3R,5R)-PIM447 dihydrochloride
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    (1S,3R,5R)-PIM447 dihydrochloride

    <p>(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).</p>
    Formula:C24H25Cl2F3N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:513.38

    Ref: TM-T13425

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    Uridine-5-oxo-acetyl-(9-fluorenylmethyl) ester

    <p>Uridine analogue with antitumor effects; inhibits DNA synthesis, induces apoptosis in lymphoid cancers.</p>
    Formula:C24H24N2O9
    Color and Shape:Solid
    Molecular weight:484.46

    Ref: TM-T75087

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    N1-Methyl-2'-O-(2-methoxyethyl) guanosine

    <p>N1-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.</p>
    Formula:C14H21N5O6
    Color and Shape:Solid
    Molecular weight:355.35

    Ref: TM-T75059

  • Anticancer agent 84
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    Anticancer agent 84

    CAS:
    <p>Anticancer agent 84 inhibits c-MYC transcription by stabilizing G4 structures, aiding cancer research.</p>
    Formula:C57H67N7O9
    Color and Shape:Solid
    Molecular weight:994.18

    Ref: TM-T74961

  • 5-Iminodaunorubicin
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    5-Iminodaunorubicin

    CAS:
    <p>5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.</p>
    Formula:C27H30N2O9
    Color and Shape:Solid
    Molecular weight:526.54

    Ref: TM-T72467

  • 6-Thioguanosine
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    6-Thioguanosine

    CAS:
    <p>6-Thioguanosine (6-Mercaptoguanosine) is an active nucleoside and low molecular weight gel.6-Thioguanosine has immunosuppressive properties.</p>
    Formula:C10H13N5O4S
    Purity:97.05%
    Color and Shape:Yellow-Green Powder
    Molecular weight:299.31

    Ref: TM-T20511