Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(546 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(47 products)
- Dynamin(27 products)
- Ferroptosis(226 products)
- HSP(179 products)
- Integrin(253 products)
- Kinesin(87 products)
- LIM Kinase(20 products)
- Microtubule Associated(273 products)
- PKC(126 products)
- PLK(25 products)
- ROCK(62 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(76 products)
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Found 3877 products of "Cell Cycle/Checkpoint"
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Anticancer agent 263
Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.Formula:C13H20N2O6Color and Shape:SolidMolecular weight:300.308Mumefural
CAS:Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.
Formula:C12H12O9Color and Shape:SolidMolecular weight:300.22Biotin-PEG7-C2-NH-Vidarabine-S-CH3
Biotin-PEG7-C2-NH-Vidarabine-S-CH3 is a PEG linker with Vidarabine, an anti-herpes/zoster antiviral.Formula:C37H62N8O12S2Color and Shape:SolidMolecular weight:875.06L-Inosine
CAS:L-Inosine, an endogenous purine nucleoside from adenosine metabolism, has anti-inflammatory, antinociceptive, immunomodulatory, and neuroprotective properties.Formula:C10H12N4O5Color and Shape:SolidMolecular weight:268.23Fostroxacitabine bralpamide
CAS:Fostroxacitabine bralpamide (MIV-818) is an orally active Troxacitabine-based nucleotide prodrug. Fostroxacitabine bralpamide has anticancer effects.Formula:C22H30BrN4O8PColor and Shape:SolidMolecular weight:589.37(R)-N-(2,3-Dihydro-1H-indenyl)-2-amino adenosine
(R)-N-(2,3-Dihydro-1H-indenyl)-2-amino adenosine, a purine analog, targets lymphoid cancer via DNA synthesis inhibition and apoptosis.Formula:C19H22N6O4Color and Shape:SolidMolecular weight:398.42Pseudorabies virus-IN-1
Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.Formula:C27H23ClF2N4O2Color and Shape:SolidMolecular weight:508.9472-(P-Cyanophenyl methylidene hydrazino) adenosine
2-(P-Cyanophenyl methylidene hydrazino) adenosine: a purine analog with antitumor effects via DNA synthesis inhibition and apoptosis.Formula:C18H18N8O4Color and Shape:SolidMolecular weight:410.395-Iminodaunorubicin
CAS:5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.Formula:C27H30N2O9Color and Shape:SolidMolecular weight:526.54NUAK1-IN-1
NUAK1-IN-1 (Compound 9) is an inhibitor of NUAK1 with an IC50 of 5.012 nM, as well as a CDK4 inhibitor. It is suitable for research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.Formula:C25H30N6OColor and Shape:SolidMolecular weight:430.545N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine
N6-Benzoyl-3'-O-DMT-adenosine is a purine analog with antitumor effects by hindering DNA synthesis and inducing apoptosis.Formula:C41H41N5O8Color and Shape:SolidMolecular weight:731.792'-O-Me-5-I-U-3'-phosphoramidite
2’-O-Me-5-I-U-3’-phosphoramidite, a purine nucleoside analog, exhibits extensive antitumor activity primarily against indolent lymphoid malignancies.Formula:C40H48IN4O9PColor and Shape:SolidMolecular weight:886.715'-O-DMTr-2',2'-difluoro-dC(Bz)-methyl phosphonamidite
5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite is a purine nucleoside analog with extensive antitumor activity against indolent lymphoid malignancies.Formula:C44H49F2N4O7PColor and Shape:SolidMolecular weight:814.85Diguanosine 5′-triphosphate
CAS:Diguanosine 5′-triphosphate (Gp3G) is a kind of homodinucleotide from by GTP:GTP guanylyltransferase.Formula:C20H27N10O18P3Color and Shape:SolidMolecular weight:788.409Lorutengitide
CAS:Lorutengitide is a transcription-regulating peptide with antiproliferative activity.Formula:C30H50N8O12Color and Shape:SolidMolecular weight:714.764Brr2-IN-2
Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.Formula:C21H25FN4O2Color and Shape:SolidMolecular weight:384.455'-O-TBDMS-N2-ibu-dG
CAS:5'-O-TBDMS-N2-ibu-dG: a nucleoside derivative with strong anti-BVDV activity, useful in lead compound synthesis.Formula:C20H33N5O5SiColor and Shape:SolidMolecular weight:451.59m7GpppCmpG
CAS:m7GpppCmpG, a trinucleotide cap analogue, enables RNA manufacturing with cap 0 or cap 1 structures.Formula:C31H43N13O25P4Color and Shape:SolidMolecular weight:1121.6413-TP
13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.Formula:C12H19F2N6O12P3Color and Shape:SolidMolecular weight:570.23ONX 0801 trisodium
CAS:ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor.Formula:C32H30N5Na3O10Color and Shape:SolidMolecular weight:713.58
