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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3477 products of "Cell Cycle/Checkpoint"

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  • Antibacterial agent 144


    <p>Antibacterial Agent 144 (compound 8e) exhibits superior efficacy against multi-resistant Staphylococcus aureus compared to Chloromycin and Amoxicillin.</p>
    Formula:C26H23N7O3
    Color and Shape:Solid
    Molecular weight:481.51
  • CDK5-IN-1

    CAS:
    <p>CDK5-IN-1: Potent CDK5 inhibitor (&lt;10 nM) used in kidney disease research.</p>
    Formula:C24H25FN6O3S
    Color and Shape:Solid
    Molecular weight:496.56
  • Gantofiban

    CAS:
    <p>Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.</p>
    Formula:C21H29N5O6
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:447.48
  • (E/Z)-THZ1 2HCl

    CAS:
    <p>THZ1 2HCl: selective CDK7 allosteric inhibitor, IC50 3.2 nM, hinders cancer cell growth.</p>
    Formula:C31H30Cl3N7O2
    Purity:99.51%
    Color and Shape:Solid
    Molecular weight:638.98
  • 5'-O-DMT-ibu-dC

    CAS:
    <p>5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.</p>
    Formula:C34H37N3O7
    Color and Shape:Solid
    Molecular weight:599.67
  • CDK7-IN-5

    CAS:
    <p>CDK7-IN-5, a CDK7 inhibitor with an IC 50 value of less than 100 nM, exhibits potent anticancer properties (WO2015154022A1, Compound 104).</p>
    Formula:C34H45N9O2
    Color and Shape:Solid
    Molecular weight:611.795
  • Remdesivir nucleoside monophosphate

    CAS:
    <p>Remdesivir metabolite, antiviral nucleoside analog, effective against SARS-CoV and MERS-CoV.</p>
    Formula:C12H14N5O7P
    Color and Shape:Solid
    Molecular weight:371.24
  • N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium

    CAS:
    <p>N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium, a dinucleotide cap analog, facilitates in vitro RNA transcription [1].</p>
    Formula:C21H35N12O17P3
    Color and Shape:Solid
    Molecular weight:820.49
  • GK13S


    <p>G13KS: UCHL1 ligand, deubiquitinase inhibitor; reduces monoubiquitin in glioblastoma cells.</p>
    Formula:C21H22N6O2
    Color and Shape:Solid
    Molecular weight:390.44
  • Chrexanthomycin C


    <p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>
    Formula:C31H24O15
    Color and Shape:Solid
    Molecular weight:636.51
  • 5'-O-DMT-N4-Bz-2'-F-dC

    CAS:
    <p>5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.</p>
    Formula:C37H34FN3O7
    Color and Shape:Solid
    Molecular weight:651.68
  • UnyLinker 12 TEA


    <p>UnyLinker 12 TEA is a versatile linker used in the synthesis of oligoribonucleotides.</p>
    Formula:C39H35NO10C6H15N
    Color and Shape:Solid
    Molecular weight:778.34655
  • α2β1 Integrin Ligand Peptide

    CAS:
    <p>The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular</p>
    Formula:C14H22N4O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:390.35
  • Barasertib

    CAS:
    <p>AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.</p>
    Formula:C26H31FN7O6P
    Purity:99.63% - 99.92%
    Color and Shape:Solid
    Molecular weight:587.54
  • 5'-O-DMT-PAC-dA

    CAS:
    <p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>
    Formula:C39H37N5O7
    Color and Shape:Solid
    Molecular weight:687.74
  • KIF2C-IN-1


    <p>KIF2C-IN-1 (Compound 7S9) is a selective and potent small molecule inhibitor of KIF2C. It stabilizes the interaction between KIF2C and microtubule proteins, preventing the depolymerization of polyglutamylated microtubules. KIF2C-IN-1 enhances the cytotoxicity of Paclitaxel in Paclitaxel-resistant triple-negative breast cancer (TNBC) cells and, when combined with Paclitaxel, significantly reduces tumor growth in mouse models.</p>
    Formula:C36H39ClN4O9S
    Color and Shape:Solid
    Molecular weight:738.21263
  • PAT-LM1


    <p>PAT-LM1 is a human monoclonal antibody that targets NRB54/NONO. It is applicable in the study of hematological malignancies.</p>
    Color and Shape:Odour Liquid
  • 3'-Deoxyuridine-5'-triphosphate trisodium


    <p>3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).</p>
    Formula:C9H12N2Na3O14P3
    Color and Shape:Soild
    Molecular weight:534.08
  • CDK6/9-IN-1

    CAS:
    <p>CDK6/9-IN-1, an oral dual inhibitor of CDK6/9, has IC50s of 40.5nM (CDK6) and 39.5nM (CDK9).</p>
    Formula:C22H25ClN8O
    Color and Shape:Solid
    Molecular weight:452.95
  • wrwyar-NH2 TFA


    <p>wrwyar-NH2 (TFA) serves as the control peptide for wrwycr-NH2.</p>
    Color and Shape:Odour Solid