Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(546 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(47 products)
- Dynamin(27 products)
- Ferroptosis(227 products)
- HSP(179 products)
- Integrin(262 products)
- Kinesin(87 products)
- LIM Kinase(20 products)
- Microtubule Associated(274 products)
- PKC(126 products)
- PLK(25 products)
- ROCK(62 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(76 products)
Show 10 more subcategories
Found 3888 products of "Cell Cycle/Checkpoint"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
MtTMPK-IN-9
MtTMPK-IN-9 moderately inhibits MtbTMPK (IC50: 48 μM), has submicromolar Mycobacterium activity, and is non-toxic, aiding tuberculosis research.Formula:C25H26N6O7Color and Shape:SolidMolecular weight:522.51LNA-CTP
CAS:LNA-CTP is a nucleotide analog utilized in the synthesis of oligonucleotides.
Formula:C10H16N3O14P3Color and Shape:SolidMolecular weight:495.17Aurora B inhibitor 1
CAS:Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor (Ki <0.010 uM) with potential anticancer activity for cancer research.Formula:C25H26ClF2N7O2Purity:98.37%Color and Shape:SolidMolecular weight:529.972′-OMe-UMP
CAS:2′-OMe-UMP is a nucleotide analog used in the synthesis of oligonucleotides.Formula:C10H15N2O9PMolecular weight:338.21WRN inhibitor 11
CAS:WRN inhibitor 11 (Example 17) is an orally effective inhibitor of WRN helicase, with an IC50 of 63 nM.Formula:C34H35ClF3N9O5Color and Shape:SolidMolecular weight:742.15UM-C162
CAS:UM-C162, a benzimidazole derivative, offers protection to nematodes from Staphylococcus aureus infections. It inhibits biofilm formation without impairing bacterial viability. Additionally, UM-C162 disrupts the production of Staphylococcus aureus hemolysins, proteases, and coagulases. This compound holds potential as an antivirulence agent for managing Staphylococcus aureus infections.Formula:C30H25N3O4Color and Shape:SolidMolecular weight:491.54Antiangiogenic agent 2
Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.
Formula:C26H26FN3O4Color and Shape:SolidMolecular weight:463.5MtTMPK-IN-8
MtTMPK-IN-8 inhibits MtbTMPK, has low cytotoxicity, shows 0.78-9.4 μM activity against Mycobacterium, useful for tuberculosis research.Formula:C24H24N6O7Color and Shape:SolidMolecular weight:508.48CDK4/6-IN-3
CAS:CDK4/6-IN-3 is a brain-penetrant CDK4/CDK6 inhibitor (Kis: <0.3 nM and 2.2 nM) used for the treatment of glioblastoma. It inhibits CDK1 with a Ki of 110 nM.Formula:C25H31FN8Purity:98%Color and Shape:SolidMolecular weight:462.57Elacytarabine
CAS:Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors.Formula:C27H45N3O6Purity:97.69%Color and Shape:SolidMolecular weight:507.66Zelasudil
CAS:Zelasudil (RXC007) is a Rho-related (ROCK) kinase inhibitor for the study of idiopathic pulmonary fibrosis and inflammation.Formula:C22H21F2N7OPurity:99.15%Color and Shape:SolidMolecular weight:437.445Ref: TM-T69665
1mg92.00€5mg168.00€10mg248.00€25mg421.00€50mg587.00€100mg820.00€1mL*10mM (DMSO)170.00€USP15-IN-1
CAS:USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM).Formula:C22H23N3O3Purity:99.509% - 99.81%Color and Shape:SolidMolecular weight:377.44GFB-12811
CAS:GFB-12811 is an orally active, selective, and potent CDK5 inhibitor, used in the study of autosomal dominant polycystic kidney disease.Formula:C22H23F4N5OPurity:98.88%Color and Shape:SolidMolecular weight:449.44HRO761
CAS:HRO761 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.Formula:C31H31ClF3N9O5Purity:98.74% - 99.62%Color and Shape:SolidMolecular weight:702.08Ref: TM-T72107
1mg57.00€5mg118.00€10mg167.00€25mg280.00€50mg475.00€100mg708.00€1mL*10mM (DMSO)778.00€CTPS1-IN-1
CAS:CTPS1-IN-1 is a cytidine-5′ triphosphate synthase 1 (CTPS1) inhibitor with potential antitumor activity and can be used to study autoimmune diseases.Formula:C21H22N6O4S2Purity:99.46%Color and Shape:SolidMolecular weight:486.57VCPIP1-IN-1
CAS:VCPIP1-IN-1 is a VCPIP1 inhibitor used in cancer research.Formula:C13H15ClN2O2Purity:99.3%Color and Shape:SolidMolecular weight:266.72Ref: TM-T88664
1mg47.00€5mg92.00€10mg145.00€25mg281.00€50mg447.00€100mg715.00€200mg964.00€1mL*10mM (DMSO)101.00€LY3143921 hydrate
CAS:LY3143921 ((S)-Example 2) hydrate is an orally active CDC7 kinase inhibitor with broad in vitro anticancer activity [1].Formula:C16H14FN5O2Purity:98.43%Color and Shape:SolidMolecular weight:327.31SR 11302
CAS:SR 11302 is an inhibitor of activator protein-1 (AP-1).Formula:C26H32O2Purity:98.65%Color and Shape:SolidMolecular weight:376.53Ref: TM-T23384
1mg93.00€5mg137.00€10mg205.00€25mg356.00€50mg587.00€100mg888.00€1mL*10mM (DMSO)150.00€INCB086550
CAS:INCB086550 (PD-1/PD-L1-IN-8) (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM.Formula:C41H39N7O4Purity:98.49%Color and Shape:SolidMolecular weight:693.79Bicyclomycin benzoate
CAS:Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.Formula:C19H22N2O8Color and Shape:SolidMolecular weight:406.39Troxacitabine
CAS:Troxacitabine, a DNA polymerase inhibitor, is potentially used for the treatment of acute myeloid leukemia (AML). In comparison with gemcitabine, troxacitabine was equally active against MiaPaCa and was more efficacious against Panc-01.Formula:C8H11N3O4Purity:98%Color and Shape:SolidMolecular weight:213.195'-O-DMT-N6-ibu-dA
CAS:5'-O-DMT-N6-ibu-dA can be utilized in the synthesis of oligodeoxyribonucleotides.Formula:C35H37N5O6Color and Shape:SolidMolecular weight:623.71Ethynylcytidine
CAS:Ethynylcytidine is a nucleoside antimetabolite.Formula:C11H13N3O5Purity:98%Color and Shape:SolidMolecular weight:267.24Tanuxiciclib
CAS:Tanuxiciclib is a cyclin dependent kinase (CDK) inhibitor, specifically designed to interfere with cell cycle progression by inhibiting the activity of CDKs, which are crucial regulators of cell division.Formula:C15H13FN6OColor and Shape:SolidMolecular weight:312.308Formycin A
CAS:Formycin A shows antitumor and antiviral activities. Formycin A , a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM.Formula:C10H13N5O4Purity:98%Color and Shape:SolidMolecular weight:267.24NSC639828
CAS:NSC639828 is an efficient inhibitor of DNA polymerase α, exhibiting a remarkable IC50 value of 70 μM. Additionally, NSC639828 demonstrates substantial antitumor activity, making it a promising candidate for cancer research.Formula:C18H13BrClN5O3Color and Shape:SolidMolecular weight:462.69GSK-3/CDK5/CDK2-IN-1
CAS:GSK-3/CDK5/CDK2-IN-1 is an imidazole derivative compound that inhibits cdk5, cdk2, and GSK-3.it has demonstrated applications in cancer research and the study of neurodegenerative diseases [1].Formula:C21H22N4O2Color and Shape:SolidMolecular weight:362.4333BrB-PP1
CAS:3BrB-PP1 is an ATP-competitive analog that exhibits specific inhibitory activity towards protein kinase, particularly effective against protein kinases with mutations in the ATP-binding pocket, such as the Thr97 mutation within Sty1's ATP-binding pocket.Formula:C16H18BrN5Color and Shape:SolidMolecular weight:360.2592'-Deoxy-2'-fluoro-5-iodouridine
CAS:2'-Deoxy-2'-fluoro-5-iodouridine is a nucleoside, specifically a fluoro-modified and halo-nucleoside.Formula:C9H10FIN2O5Color and Shape:SolidMolecular weight:372.09PLK1-IN-6
PLK1-IN-6: potent, selective PLK1 inhibitor, IC50 = 0.45 nM, hinders cancer cell growth.
Formula:C28H37N9O3Color and Shape:SolidMolecular weight:547.655'-DMT-3'-TBDMS-ibu-rG
CAS:5'-DMT-3'-TBDMS-ibu-rG is a modified nucleoside employed in deoxyribonucleic acid (DNA) synthesis.Formula:C41H51N5O8SiColor and Shape:SolidMolecular weight:769.96N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine
CAS:N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine, catalog number T66118 and CAS number 64325-78-6, is a valuable organic compound for life sciences research.Formula:C38H35N5O6Color and Shape:SolidMolecular weight:657.727MitoE10
CAS:MitoE10 is an effective mitochondrial targeting antioxidant.Formula:C42H55O5PSColor and Shape:SolidMolecular weight:702.92Ribocil-C
CAS:Ribocil-C is a selective inhibitor of the bacterial riboflavin riboswitch, a synthetic analogue of flavin mononucleotide (FMN), inhibits bacterial cell growth.Formula:C21H21N7OSPurity:98%Color and Shape:SolidMolecular weight:419.56-Amino-5-nitropyridin-2-one
CAS:6-Amino-5-nitropyridin-2-one, a pyridine derivative, serves as a nucleobase within hachimoji DNA, where it is specifically paired with 5-aza-7-deazaguanine.Formula:C5H5N3O3Purity:98%Color and Shape:SolidMolecular weight:155.11Tibremciclib
CAS:Tibremciclib is a cyclin-dependent kinase 4 (CDK4) inhibitor that exhibits antineoplastic properties [1].
Formula:C28H32F2N8Purity:98%Color and Shape:SolidMolecular weight:518.6PHI-101
CAS:PHI-101 is a checkpoint kinase 2 (Chk2) inhibitor that can be used for the study of refractory acute myeloid leukemia (AML) and ovarian cancer.
Formula:C19H19FN4O2SPurity:99.4%Color and Shape:SolidMolecular weight:386.44YK-2168
CAS:YK-2168 is a differentiated selective inhibitor of CDK9.
Formula:C16H18ClN5Color and Shape:SolidMolecular weight:315.80Ref: TM-T200769
Discontinued product
