
Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(109 products)
- CDK(522 products)
- Cell Cycle Arrest(4 products)
- Chk(46 products)
- DYRK(49 products)
- Dynamin(26 products)
- Ferroptosis(223 products)
- HSP(179 products)
- Integrin(256 products)
- Kinesin(83 products)
- LIM Kinase(19 products)
- Microtubule Associated(284 products)
- PKC(111 products)
- PLK(25 products)
- ROCK(67 products)
- Rho(2 products)
- Wee1(14 products)
- c-Myc(74 products)
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Found 3730 products of "Cell Cycle/Checkpoint"
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Bis-Pro-5FU
CAS:Bis-Pro-5FU enhances oral uptake and safety of 5-FU, an anti-cancer drug for colorectal and pancreatic tumors.Formula:C10H7FN2O2Color and Shape:SolidMolecular weight:206.17Fozivudine tidoxil
CAS:Fozivudine tidoxil, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Formula:C35H64N5O8PSColor and Shape:SolidMolecular weight:745.95Aditoprime
CAS:Aditoprime inhibits bacterial growth by blocking DHFR, effective against L.casei and E.coli with IC50 of 520/47 nM.Formula:C15H21N5O2Color and Shape:SolidMolecular weight:303.36(R)-Filanesib
CAS:(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).Formula:C20H22F2N4O2SColor and Shape:SolidMolecular weight:420.48CDK4/6-IN-8
CAS:CDK4/6-IN-8 (Compound 7p) is a selective inhibitor of CDK4 (IC50=5.01 nM) and CDK6 (IC50=3.97 nM).Formula:C18H18N6O5Color and Shape:SolidMolecular weight:398.37L-Fd4A
CAS:L-Fd4A (compound 36) is an adenine derivative with anti-HIV (EC50=1.5μM) and anti-HBV (EC50=1.7μM) effects, low cytotoxicity.Formula:C10H10FN5O2Color and Shape:SolidMolecular weight:251.222-Keto-D-galactose
CAS:2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.Formula:C6H10O6Purity:98%Color and Shape:SolidMolecular weight:178.14IMB-10
CAS:IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.Formula:C19H15NOS2Color and Shape:SolidMolecular weight:337.46MtTMPK-IN-6
CAS:MtTMPK-IN-6 inhibits M. tuberculosis thymidylate kinase with IC50 of 29 μM, promising for TB research.Formula:C23H25N3O3Color and Shape:SolidMolecular weight:391.46CAP-53194
CAS:CAP-53194 is a selective Plk1 inhibitor.Formula:C21H14N6O5Purity:98%Color and Shape:SolidMolecular weight:430.37CDK9-IN-14
CAS:CDK9-IN-14: Potent CDK9 inhibitor, IC50=6.92 nM, effective on MV-4-11 cells and in vivo tumors, low toxicity, minimal side effects.Formula:C21H23F2N3O4Color and Shape:SolidMolecular weight:419.42GSK-3008348
CAS:GSK-3008348 is an antagonist of integrin alpha(v)beta6.Formula:C29H37N5O2Purity:99.547%Color and Shape:SolidMolecular weight:487.64Mivobulin Isethionate
CAS:Mivobulin, a tubulin inhibitor (CI-980), may treat glioma, melanoma, prostate, and ovarian cancer, targeting colchicine-binding site.Formula:C19H25N5O6SPurity:98%Color and Shape:SolidMolecular weight:451.5Picoplatin
CAS:Picoplatin, an anti-cancer agent overcoming platinum resistance, alkylates DNA to block replication, transcription, and induce apoptosis.Formula:C6H10Cl2N2PtPurity:98%Color and Shape:SolidMolecular weight:376.14HHL-6
CAS:HHL-6 is a c-Fos and BDNF protein expression modulator.Formula:C19H26N2O3Color and Shape:SolidMolecular weight:330.42Poloxipan
CAS:Poloxipan inhibits PLK1 (IC50: 3.2µM), PLK2 (1.7µM), PLK3 (3µM); minimal effect on Chk2, STAT1, STAT5b, Lck.Formula:C14H10BrN3O3SColor and Shape:SolidMolecular weight:380.22Metralindole HCl
CAS:Metralindole is a reversible monoamine oxidase A (RIMA) inhibitor, it was investigated as a potential antidepressant.Formula:C15H18ClN3OPurity:98%Color and Shape:SolidMolecular weight:291.78HR22C16
CAS:HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.Formula:C23H23N3O3Color and Shape:SolidMolecular weight:389.45HIPP
CAS:HIPP is a highly selective inhibitor of antineoplastic CtBP.Formula:C9H9NO3Color and Shape:SolidMolecular weight:179.17NPD9948
CAS:NPD9948 is a competitive inhibitor of MTH1.Formula:C13H14N6Color and Shape:SolidMolecular weight:254.29LDN-209929
CAS:LDN-209929 2HCl is a potent and selective inhibitor of haspin kinase.Formula:C17H17ClN2OSColor and Shape:SolidMolecular weight:332.85DDD100097
CAS:DDD100097 is a N-myristoyltransferase inhibitor with potential inhibitory effects on Trypanosoma brucei, which can be used to study neurological disorders.Formula:C22H30Cl2F2N4O2SPurity:98.89%Color and Shape:SolidMolecular weight:523.47DYRKi
CAS:DYRKi is a nontoxic, DYRK1-selective inhibitor.Formula:C20H13F3N4O2SColor and Shape:SolidMolecular weight:430.4BIPM
CAS:BIPM inhibits ROCK2, alters SH-SY5Y cell migration, actin fibers, neurite length, and reduces cofilin phosphorylation.Formula:C23H22N2O3Color and Shape:SolidMolecular weight:374.43JA2131
CAS:JA2131: Small PARG inhibitor, IC50 0.4μM, induces DNA damage, stalls replication, kills cancer cells.Formula:C13H19N5O2S2Color and Shape:SolidMolecular weight:341.45ERCC1-XPF-IN-1
CAS:ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.Formula:C28H32ClN5O2Color and Shape:SolidMolecular weight:506.04Antibacterial agent 124
CAS:Antibacterial agent 124 inhibits Sa ProRS with an IC50 of 0.18 μM.Formula:C16H17ClFN3O2Color and Shape:SolidMolecular weight:337.78ML372
CAS:ML372 is a potent and selective SMN Modulator (EC50 = 12 nM, 325% increase inSMN2) with good potency, pharmacokinetics, tolerance, and CNS penetration.Formula:C18H20N2O4SColor and Shape:SolidMolecular weight:360.43BMS-587101
CAS:BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.Formula:C26H20Cl2N4O4SColor and Shape:SolidMolecular weight:555.43CDK7-IN-15
CAS:CDK7-IN-15, a pyrimidine-based potent CDK7 inhibitor, shows promise for various cancers with defective transcription.Formula:C21H24F4N6OSPurity:99.27%Color and Shape:SolidMolecular weight:484.51REV7/REV3L-IN-1
CAS:REV7/REV3L-IN-1 is a inhibitor of REV7/REV3L interaction(IC50 of 78 μM),Formula:C19H21N3O3SPurity:98%Color and Shape:SolidMolecular weight:371.45NSC47924
CAS:NSC47924 is a laminin receptor (LR) inhibitor.Formula:C18H17NO2Purity:98%Color and Shape:SolidMolecular weight:279.33AB-182
CAS:AB-182 is an aziridine derivative with antitumor activity.Formula:C11H22N3O4PColor and Shape:SolidMolecular weight:291.28Dyrk1A-IN-3
CAS:Dyrk1A-IN-3 is a selective DYRK1A inhibitor with an IC50 of 76 nM, useful for neurodegenerative disease research.Formula:C18H16N6Color and Shape:SolidMolecular weight:316.36Ro 43-5054
CAS:Ro 43-5054 is a small molecular, noncyclic peptidomimetic inhibitor.Formula:C24H27N5O7Purity:98%Color and Shape:SolidMolecular weight:497.5ROCK-IN-D1
CAS:ROCK-IN-D1 is an effective and selective inhibitor of ROCK.Formula:C22H27N5O2SPurity:98%Color and Shape:SolidMolecular weight:425.55Nucleoside-Analog-1
CAS:Nucleoside-Analog-1 is a 4′-Azidocytidine analogue, used to against Hepatitis C virus replication.Formula:C9H9N5O5Purity:98%Color and Shape:SolidMolecular weight:267.2SNX2-1-108
CAS:SNX2-1-108 is a selective CDK8 and CDK19 inhibitor.Formula:C21H16N4Purity:98%Color and Shape:SolidMolecular weight:324.38PKC-9
CAS:PKC-9 is a PKC-zeta inhibitor 9.Formula:C25H25N7Color and Shape:SolidMolecular weight:423.51LIMK-IN-14
CAS:LIMK-IN-14 is an effective and selective inhibitor of LIMK.Formula:C22H27N7O3Purity:98%Color and Shape:SolidMolecular weight:437.49Valategrast hydrochloride
CAS:Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.Formula:C30H33Cl4N3O4Purity:98%Color and Shape:SolidMolecular weight:641.41Denopterin
CAS:Denopterin is an antineoplastic agent.Formula:C21H23N7O6Purity:98%Color and Shape:SolidMolecular weight:469.45Tenofovir exalidex
CAS:Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistantFormula:C28H52N5O5PPurity:99.83%Color and Shape:SolidMolecular weight:569.721-Acetyl-3-o-toluyl-5-fluorouracil
CAS:<p>1-Acetyl-3-o-toluyl-5-fluorouracil is a potent antineoplastic agent.</p>Formula:C14H11FN2O4Purity:98%Color and Shape:SolidMolecular weight:290.25BPIC
CAS:BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.Formula:C27H20N2O5Color and Shape:SolidMolecular weight:452.46Rabacfosadine succinate
CAS:Rabacfosadine succinate is the acyclic nucleoside phosphonate PMEG double prodrug.Formula:C25H41N8O10PPurity:98%Color and Shape:SolidMolecular weight:644.623Thiamiprine
CAS:Thiamiprine is an agent with the activity of antineoplastic.Formula:C9H8N8O2SColor and Shape:SolidMolecular weight:292.28Meturedepa
CAS:Meturedepa is an antineoplastic agent.Formula:C11H22N3O3PPurity:98%Color and Shape:SolidMolecular weight:275.28CLK1-IN-2
CLK1-IN-2: Metabolically stable, Clk1-selective inhibitor; IC50=1.7nM; useful in tumor, Duchenne MD, HIV-1, influenza research.Formula:C16H12Cl2N2O2SColor and Shape:SolidMolecular weight:367.25TDRL-X80
CAS:TDRL-X80 inhibits XPA DNA binding; effective on single, double, and cisplatin-damaged DNA; IC50: 18-29 μM (FP), 21-39 μM (ELISA).Formula:C23H15ClN2O6Color and Shape:SolidMolecular weight:450.83
