
Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(111 products)
- CDK(525 products)
- Cell Cycle Arrest(4 products)
- Chk(46 products)
- DYRK(49 products)
- Dynamin(26 products)
- Ferroptosis(224 products)
- HSP(180 products)
- Integrin(256 products)
- Kinesin(86 products)
- LIM Kinase(19 products)
- Microtubule Associated(284 products)
- PKC(111 products)
- PLK(25 products)
- ROCK(66 products)
- Rho(2 products)
- Wee1(14 products)
- c-Myc(75 products)
Show 10 more subcategories
Found 3749 products of "Cell Cycle/Checkpoint"
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A 65281
CAS:A 65281: antibacterial isothiazoloquinolone, inhibits P4-unknotting, induces DNA breakage via topoisomerase II.Formula:C17H16F2N4O2SPurity:98%Color and Shape:SolidMolecular weight:378.4FUBP1-IN-2
CAS:FUBP1-IN-2 hinders FUBP1, affects c-Myc and p21 expression, and depletes polyamines.Formula:C26H26ClN3O4Color and Shape:SolidMolecular weight:479.96DNA Gyrase-IN-4
CAS:DNA Gyrase-IN-4 inhibits DNA cyclooxygenase (IC50: 0.13 μM) and is effective against Salmonella and E. coli.Formula:C22H15Cl2NO4SColor and Shape:SolidMolecular weight:460.33NSC 625987
CAS:Cyclin-dependent kinase (cdk) 4 inhibitorFormula:C15H13NO2SPurity:98%Color and Shape:SolidMolecular weight:271.33Cdc7-IN-13
CAS:Cdc7-IN-13 (compound 84) is a highly potent CDC7 inhibitor, exhibiting an IC50 value of <1 nM. This compound holds promise for cancer research [1].Formula:C18H20N4O2SColor and Shape:SolidMolecular weight:356.44Capzimin
CAS:<p>Capzimin is a selective inhibitor of proteasome isopeptidase Rpn11.</p>Formula:C30H24N6O2S4Purity:98.31% - 99.32%Color and Shape:SolidMolecular weight:628.81(E/Z)-BIO-acetoxime
CAS:(E/Z)-BIO-acetoxime: potent GSK-3 α/β inhibitor; IC50: GSK-3α/β 10nM, CDK5/p25 2.4μM, CDK2/A 4.3μM, CDK1/B 63μM.Formula:C18H12BrN3O3Color and Shape:SolidMolecular weight:398.21Zaurategrast ethyl ester
CAS:Zaurategrast ethyl ester, an α4β1/α4β7 integrin antagonist prodrug of CT7758, treats inflammatory/autoimmune conditions.Formula:C28H29BrN4O3Purity:98%Color and Shape:SolidMolecular weight:549.46β-catenin-IN-3
CAS:β-catenin-IN-3 is a selective and potent β-catenin inhibitor (KD: 54.96 nM) that targets a cryptic regulatory site of β-catenin and significantly reduces theFormula:C19H20Br2N2OSColor and Shape:SolidMolecular weight:484.255-Ethynyluridine
CAS:5-Ethynyluridine marks new RNA for RICK, capturing proteins on various RNAs, even nonpolyadenylated types.Formula:C11H12N2O6Purity:99.78%Color and Shape:SolidMolecular weight:268.22BzDANP
CAS:BzDANP is a modulator of pre-miR-29a maturation by Dicer.Formula:C18H24N6Color and Shape:SolidMolecular weight:324.42Lysine-methotrexate
CAS:Lysine-methotrexate is an anticancer drug. It is an inhibitor of dihydrofolate reductase.Formula:C21H27N9O3Purity:98%Color and Shape:SolidMolecular weight:453.55-OHdU
CAS:<p>5-OHdU (5-OHdU) is a major oxidation product of 2'-Deoxycytidine and can be incorporated into DNA in vitro.</p>Formula:C9H12N2O6Purity:99.5%Color and Shape:SolidMolecular weight:244.2BAY-958
CAS:BAY-958 is a potent and selective inhibitor of PTEFb/CDK9.Formula:C17H16FN5O3SPurity:98%Color and Shape:SolidMolecular weight:389.4L 703014
CAS:L 703014 is an antagonist of the fibrinogen receptor.Formula:C24H34N4O4Purity:98%Color and Shape:SolidMolecular weight:442.55SEC inhibitor KL-2
CAS:KL-2: potent SEC inhibitor, selectively disrupts AFF4-CCNT1, dose-dependent, Ki: 1.50 μM.Formula:C17H13ClFNO3Purity:99.86%Color and Shape:SolidMolecular weight:333.74BRD9185
CAS:BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.Formula:C23H21F6N3O2Purity:98%Color and Shape:SolidMolecular weight:485.42DHODH-IN-1
CAS:<p>DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.</p>Formula:C21H20F3N3O2Purity:99.76%Color and Shape:SolidMolecular weight:403.4CID 5951923
CAS:CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.Formula:C16H18N2O7SPurity:99.95%Color and Shape:SolidMolecular weight:382.39Aurora A/PKC-IN-1
CAS:Aurora A/PKC-IN-1 inhibits AurA (IC50: 6.9 nM), PKCα (IC50: 16.9 nM), and hinders breast cancer cell growth and spread.Formula:C16H14N6OSe2Color and Shape:SolidMolecular weight:464.24APC 366
CAS:APC 366: Mast cell tryptase inhibitor, Ki 7.1 μM. Reduces EAR, LAR, BHR in allergic asthma (sheep model).Formula:C22H28N6O4Purity:99.8%Color and Shape:SolidMolecular weight:440.5CCT245737(S)
CAS:CCT245737(S) is a highly selective oral checkpoint kinase 1 (CHK1) inhibitor.Formula:C16H16F3N7OColor and Shape:SolidMolecular weight:379.34Photoregulin3
CAS:Photoregulin3 is a inhibitor of rod photoreceptor gene expression, potentially though Nr2e3 modulation.Formula:C22H23N3O3Color and Shape:SolidMolecular weight:377.44DAP-81
CAS:DAP-81, a diaminopyrimidine, inhibits Plk1 (IC50: 0.9 nM), disrupts microtubules, causes monopolar spindles; in preclinical studies.Formula:C25H20N6O4Color and Shape:SolidMolecular weight:468.46CDK4/6-IN-9
CAS:CDK4/6-IN-9 selectively inhibits CDK4/6 (IC50: 905 nM); potential for MM research.Formula:C22H23FN8Color and Shape:SolidMolecular weight:418.47Cdc7-IN-4
CAS:Cdc7-IN-4 is a potent inhibitor of Cdc7 kinase.Formula:C22H24F3N5O4Purity:98%Color and Shape:SolidMolecular weight:479.45HBV-IN-16
CAS:HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).Formula:C22H20ClNO4Color and Shape:SolidMolecular weight:397.852-Fluoroadenine
CAS:<p>2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.</p>Formula:C5H4FN5Purity:98.84% - 99.62%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:153.12CDK7-IN-12
CAS:CDK7-IN-12 inhibits CDK7 to control transcription and cell cycle, halting tumor growth in vitro/vivo with cancer research potential.Formula:C20H19F3N6Color and Shape:SolidMolecular weight:400.4Chlorasquin
CAS:Chlorasquin is a dihydrofolate reductase inhibitor.Formula:C20H19ClN6O5Purity:98%Color and Shape:SolidMolecular weight:458.86ROCK-IN-4
CAS:ROCK-IN-4: Inhibits ROCK, sustains NO release, disrupts F-actin, hinders HTM cell respiration, aids glaucoma research.Formula:C20H26ClFN4O7SColor and Shape:SolidMolecular weight:520.96Crisnatol mesylate
CAS:Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.Formula:C24H27NO5SColor and Shape:SolidMolecular weight:441.54CDK-IN-10
CAS:CDK-IN-10 is a cell cycle protein-dependent kinase (CDK) inhibitor with potential anticancer activity for cancer research.Formula:C18H18N4O2Purity:97.07%Color and Shape:SolidMolecular weight:322.36GR 144053 trihydrochloride
CAS:platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonistFormula:C18H30Cl3N5O2Purity:98%Color and Shape:SolidMolecular weight:454.82AM-TS23
CAS:AM-TS23 is used as a DNA polymerase lambda and beta inhibitor.Formula:C17H12N2O3S3Purity:98%Color and Shape:SolidMolecular weight:388.48BOP sodium
CAS:BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.Formula:C25H29N3NaO7SColor and Shape:SolidMolecular weight:538.57NSC666715
CAS:NSC666715 is the strand-displacement activity of DNA polymerase inhibitor.Formula:C15H13Cl2N5O2S2Purity:98%Color and Shape:SolidMolecular weight:430.33Werner syndrome RecQ helicase-IN-3
CAS:Potent WRN inhibitor, Werner syndrome RecQ helicase-IN-3, is orally active with 0.06 µM IC50; exhibits antiproliferative and anticancer effects.Formula:C31H30ClF3N8O5Color and Shape:SolidMolecular weight:687.07ML366
CAS:ML366 is a Vibrio cholerae Quorum Sensing inhibitor Acting via the LuxO response regulator.Formula:C17H19N3O4Purity:98%Color and Shape:SolidMolecular weight:329.35Zaurategrast ethyl ester sulfate
CAS:Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.Formula:C56H60Br2N8O10SPurity:98%Color and Shape:SolidMolecular weight:1197.01Mps-BAY2b
CAS:Mps-BAY2b is a novel MPS1 inhibitor.Formula:C20H23N5OColor and Shape:SolidMolecular weight:349.43Beaucage reagent
CAS:Beaucage reagent, which is found to be effective in causing DNA cleavage.Formula:C7H4O3S2Purity:98.50%Color and Shape:White To Off-White PowderMolecular weight:200.23Indirubin-5-sulfonate
CAS:Indirubin-5-sulfonate inhibits GSK-3β & CDKs with IC50: 55/35/150/300/65 nM for CDK1/B, 2/A&E, 4/D1, 5/p35.Formula:C16H10N2O5SPurity:98%Color and Shape:SolidMolecular weight:342.33Cdc7-IN-9
CAS:Cdc7-IN-9 can be used for the research of cancer which is a potent inhibitor of Cdc7 [1].Formula:C15H17N5OSColor and Shape:SolidMolecular weight:315.39HBX28258
CAS:HBX28258, a human USP7 inhibitor, binds covalently and selectively deactivates USP7 in colon cancer and kidney cells.Formula:C26H30ClN3OPurity:98%Color and Shape:SolidMolecular weight:435.99Erythromycin hydrochloride
CAS:Erythromycin hydrochloride is an inhibitor of protein translation and mammalian mRNA splicing. It inhibits growth of gram negative and gram positiove bacteria.Formula:C37H68ClNO13Color and Shape:SolidMolecular weight:770.39GSK317354A
CAS:GSK317354A is a GRK2 inhibitor.Formula:C25H18F4N6OColor and Shape:SolidMolecular weight:494.44NSC 693868
CAS:CDKs and GSK-3 inhibitorFormula:C9H7N5Purity:98%Color and Shape:SolidMolecular weight:185.19Y-9738
CAS:<p>Y-9738 is an agent of hypolipidemic.</p>Formula:C15H16ClNO4Purity:98%Color and Shape:SolidMolecular weight:309.74
