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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3730 products of "Cell Cycle/Checkpoint"

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  • Pseudorabies virus-IN-1


    <p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>
    Formula:C27H23ClF2N4O2
    Color and Shape:Solid
    Molecular weight:508.947
  • Catumaxomab

    CAS:
    <p>Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.</p>
    Purity:95%
    Color and Shape:Liquid
  • STX-100


    PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.
    Purity:97.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.3% (SDS-PAGE); 97.5% (SEC-HPLC)
    Color and Shape:Odour Liquid
  • JAMM protein inhibitor 2 

    CAS:
    JAMM inhibitor 2 targets thrombin, Rpn11, MMP2 with IC50s 10, 46, 89 μM, aids cancer research.
    Formula:C21H26N2O2
    Purity:98.57%
    Color and Shape:Solid
    Molecular weight:338.44
  • Mumefural

    CAS:
    <p>Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.</p>
    Formula:C12H12O9
    Color and Shape:Solid
    Molecular weight:300.22
  • Obtustatin


    <p>Potent α1β1 integrin inhibitor, 0.8 nM IC50 for IV collagen binding. Selective over other integrins. Inhibits FGF2 angiogenesis; antitumor in mouse models.</p>
    Formula:C184H284N52O57S8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4393.07
  • 5-Iminodaunorubicin

    CAS:
    5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.
    Formula:C27H30N2O9
    Color and Shape:Solid
    Molecular weight:526.54
  • N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine


    <p>N4-Benzoyl-3'-O-DMT cytidine analog inhibits DNA methyltransferases like Zebularine.</p>
    Formula:C41H43N3O9
    Color and Shape:Solid
    Molecular weight:721.79
  • SMS 121

    CAS:
    SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.
    Formula:C20H21NO5
    Purity:98.29%
    Color and Shape:Soild
    Molecular weight:355.38
  • 6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

    CAS:
    6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, exhibits a broad spectrum of biochemical and
    Formula:C11H15N5O4
    Color and Shape:Solid
    Molecular weight:281.27
  • Farletuzumab

    CAS:
    <p>Farletuzumab (MORAb-003), a humanized antibody, inhibits FRα-expressing cell growth for cancer research.</p>
    Purity:> 95%
    Color and Shape:Liquid
    Molecular weight:145.36 kDa
  • CTP Synthetase-IN-1 Ammonium salt


    <p>CTP Synthetase-IN-1 Ammonium salt is a CTPS inhibitor with potential antibacterial, anti-inflammatory, and antitumor activity for the study of SARS-CoV-2 viral infections</p>
    Formula:C20H22F3N7O3S2
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:529.56
  • TAS-119

    CAS:
    TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95
    Formula:C23H22Cl2FN5O3
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:506.36
  • WAY-647802

    CAS:
    <p>WAY-647802 is a CDK inhibitor.</p>
    Formula:C11H14N4O3
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:250.25
  • Eesperamicin A1

    CAS:
    Esperamicin A1, a powerful antitumor drug, comes from Actinomadura verrucosospora.
    Formula:C59H80N4O22S4
    Color and Shape:Solid
    Molecular weight:1325.54
  • Echistatin

    CAS:
    Potent αVβ3 integrin blocker, stops osteoclast binding & bone loss, hinders platelet aggregation. Ki=0.27 nM, IC50s: 0.1 nM (bone), 30 nM (platelets).
    Formula:C217H341N71O74S9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:5417.1
  • Clofarabine-5'-diphosphate

    CAS:
    Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.
    Formula:C10H13ClFN5O9P2
    Color and Shape:Solid
    Molecular weight:463.64
  • Erythromycin thiocyanate

    CAS:
    Erythromycin thiocyanate, a macrolide from Streptomyces erythreus, binds 50S ribosomes, halting protein synthesis in bacteria.
    Formula:C38H68N2O13S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:793.02
  • 5'-O-DMTr-2',2'-difluoro-dC(Bz)-methyl phosphonamidite


    5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite is a purine nucleoside analog with extensive antitumor activity against indolent lymphoid malignancies.
    Formula:C44H49F2N4O7P
    Color and Shape:Solid
    Molecular weight:814.85
  • NUAK1-IN-1


    NUAK1-IN-1 (Compound 9) is an inhibitor of NUAK1 with an IC50 of 5.012 nM, as well as a CDK4 inhibitor. It is suitable for research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.
    Formula:C25H30N6O
    Color and Shape:Solid
    Molecular weight:430.545