CymitQuimica logo
Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

Show 10 more subcategories

Found 3730 products of "Cell Cycle/Checkpoint"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • PD-1/PD-L1-IN-53
    Targetmol
    + Info

    PD-1/PD-L1-IN-53

    CAS:
    <p>PD-1/PD-L1-IN-53 (compound B3) serves as an inhibitor targeting both the PD-1/PD-L1 and VISTA signaling pathways. It is utilized in cancer research.</p>
    Formula:C31H37N3O4
    Color and Shape:Solid
    Molecular weight:515.64

    Ref: TM-T200774

  • CymitQuimica logo
    Targetmol
    + Info

    2'-F-AMP

    CAS:
    2'-F-AMP is a nucleotide analogue used in the synthesis of oligonucleotides.
    Formula:C10H13FN5O6P
    Molecular weight:349.21

    Ref: TM-TSW-00945

  • CHK-IN-1
    Targetmol
    + Info

    CHK-IN-1

    CAS:
    CHK-IN-1 is a dual inhibitor of CHK1 and CHK2 with antiproliferative activity.
    Formula:C18H19ClFN5OS
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:407.89

    Ref: TM-T13148

  • CDK2-IN-30
    Targetmol
    + Info

    CDK2-IN-30

    CAS:
    <p>CDK2-IN-30 (Formula (I)) is a CDK2 inhibitor with an IC50 of ≤20 nM, utilized primarily in tumor research.</p>
    Formula:C18H25N7O3S
    Color and Shape:Solid
    Molecular weight:419.50

    Ref: TM-T200706

  • Polθ-IN-8
    Targetmol
    + Info

    Polθ-IN-8

    CAS:
    Polθ-IN-8 (example 77) is a DNA polymerase θ (Polθ) inhibitor with an IC50 for Polθ ATPase activity of less than 100 nM. Polθ-IN-8 is useful for researching diseases related to Polθ activity, such as cancer.
    Formula:C22H22ClN7O3S
    Color and Shape:Solid
    Molecular weight:499.97

    Ref: TM-T207723

  • Aurora B inhibitor 1
    Targetmol
    + Info

    Aurora B inhibitor 1

    CAS:
    Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor (Ki <0.010 uM) with potential anticancer activity for cancer research.
    Formula:C25H26ClF2N7O2
    Purity:98.37%
    Color and Shape:Solid
    Molecular weight:529.97

    Ref: TM-T12010

  • Ascofuranone
    Targetmol
    + Info

    Ascofuranone

    CAS:
    Ascofuranone is an inhibitor of the ubiquinol oxidase activity of Trypanosoma brucei mitochondrial alternative oxidase (TAO), as well as an inhibitor of HsDHODH
    Formula:C23H29ClO5
    Color and Shape:Solid
    Molecular weight:420.93

    Ref: TM-T69313

  • CDK7-IN-33
    Targetmol
    + Info

    CDK7-IN-33

    CAS:
    CDK7-IN-33 (Compound 148) is a CDK7 inhibitor with a Ki value of 21.75 nM. It suppresses the proliferation of A549 cells expressing CDK7WT, with a pIC50 of 7.37.
    Formula:C29H36N6O4S
    Color and Shape:Solid
    Molecular weight:564.699

    Ref: TM-T206088

  • CymitQuimica logo
    Targetmol
    + Info

    3-deoxy-3-fluoro-β-D-Ribofuranose 25

    CAS:
    Compound 25, β-D-Ribofuranose, 3-deoxy-3-fluoro-, 1,2-diacetate 5-(4-methylbenzoate), exhibits strong activity in inhibiting the growth of tumor cells [1].
    Formula:C17H19FO7
    Molecular weight:354.33

    Ref: TM-T87696

  • 5-Fluorouridine 5'-phosphate
    Targetmol
    + Info

    5-Fluorouridine 5'-phosphate

    CAS:
    5-Fluorouridine 5'-phosphate acts as an ODCase (uridine 5'-monophosphate decarboxylase) inhibitor, exhibiting a Ki value of 98 µM for human ODCase and 645 µM for Methanococcus jannaschii ODCase. This compound also shows inhibitory activity on leukemia and lymphoma cell lines, making it useful for cancer research studies.
    Formula:C9H12FN2O9P
    Color and Shape:Solid
    Molecular weight:342.172

    Ref: TM-T205644

  • Methyl 3-oxodecanoate
    Targetmol
    + Info

    Methyl 3-oxodecanoate

    CAS:
    <p>Methyl 3-oxodecanoate exhibits virulence factor activity against human pathogens and shows effects on Synechococcus elongatus (a species of fluorescent algae) as well as on culture supernatant. Additionally, Methyl 3-oxodecanoate inhibits DNA synthesis by suppressing protein synthesis at the translation initiation level.</p>
    Formula:C11H20O3
    Color and Shape:Solid
    Molecular weight:200.275

    Ref: TM-T206384

  • Norharmine
    Targetmol
    + Info

    Norharmine

    CAS:
    Norharmine is an analogue of harman and functions as an alkaloid. It serves as an inhibitor of both monoamine oxidase A (MAO-A) and DYRK1A. While it exhibits weak inhibitory activity against MAO-A, it has certain inhibitory effects on DYRK1A.
    Formula:C12H10N2O
    Color and Shape:Solid
    Molecular weight:198.221

    Ref: TM-T204194

  • WEE1-IN-10
    Targetmol
    + Info

    WEE1-IN-10

    CAS:
    WEE1-IN-10 is a Wee1 kinase inhibitor that inhibits the growth of LOVO cells, such as pancreatic cancer, malignant melanoma, and malignant glioma.
    Formula:C28H30Cl2N8O
    Purity:98.18%
    Color and Shape:Solid
    Molecular weight:565.5

    Ref: TM-T89365

  • Z4P
    Targetmol
    + Info

    Z4P

    CAS:
    Z4P, an IRE1 inhibitor with blood-brain barrier permeability (BBB), inhibited glioblastoma growth and recurrence in combination with Temozolomide.
    Formula:C19H24N2O2
    Purity:98.99%
    Color and Shape:Solid
    Molecular weight:312.41

    Ref: TM-T87658

  • DDO-6079
    Targetmol
    + Info

    DDO-6079

    CAS:
    DDO-6079 is an efficient CDC37 inhibitor. It suppresses the HSP90-CDC37 and CDC37-CDK4/6 chaperone complexes by binding to an allosteric site on CDC37. Additionally, DDO-6079 reduces the thermal stability of CDK6.
    Formula:C18H13ClN2O3
    Color and Shape:Solid
    Molecular weight:340.76

    Ref: TM-T204112

  • MY05
    Targetmol
    + Info

    MY05

    CAS:
    MY05 selectively targets c-MYC within cells and disrupts the interaction between MYC and MAX. It binds to intracellular c-MYC, modulating its thermal stability, reducing the transcriptional targets of c-MYC, and exhibiting anticancer activity (TNBC, triple-negative breast cancer).
    Formula:C19H11ClN4O
    Color and Shape:Solid
    Molecular weight:346.77

    Ref: TM-T206537

  • 2-CEES
    Targetmol
    + Info

    2-CEES

    CAS:
    2-CEES is a mustard gas analogue that only forms DNA monoadducts. It induces centromere amplification in both human and mouse cells and can lead to chromosome instability.
    Formula:C4H9ClS
    Color and Shape:Solid
    Molecular weight:124.632

    Ref: TM-T204286

  • 2-Amino-2'-fluoro-2'-deoxyadenosine
    Targetmol
    + Info

    2-Amino-2'-fluoro-2'-deoxyadenosine

    CAS:
    <p>2-Amino-2'-fluoro-2'-deoxyadenosine is a component of nucleic acids.</p>
    Formula:C10H13FN6O3
    Color and Shape:Solid
    Molecular weight:284.25

    Ref: TM-TSW-00955

  • PCNA-IN-1
    Targetmol
    + Info

    PCNA-IN-1

    CAS:
    PCNA-IN-1 (Compound 11) is an inhibitor of the PCNA/PIP-box interaction, with an IC50 greater than 50 μM. It is applicable in cancer research.
    Formula:C19H18I3NO3
    Color and Shape:Solid
    Molecular weight:689.065

    Ref: TM-T204170

  • 2′-F-UDP
    Targetmol
    + Info

    2′-F-UDP

    CAS:
    2′-F-UDP is a nucleotide analogue used in the synthesis of oligonucleotides.
    Formula:C9H13FN2O11P2
    Color and Shape:Solid
    Molecular weight:406.15

    Ref: TM-TSW-00958