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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3726 products of "Cell Cycle/Checkpoint"

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  • NRTT-IN-1

    CAS:
    <p>NRTT-IN-1 (Compound 1) is an inhibitor of the nucleoside reverse transcriptase translocation (NRTT), effectively blocking HIV DNA synthesis and viral replication.</p>
    Formula:C28H24FN5O5
    Color and Shape:Solid
    Molecular weight:529.519
  • Aurora A inhibitor 1

    CAS:
    Aurora A inhibitor 1: potent, selective, targets cancer-linked Aurora A overexpression, potential for cancer research. (WO2021147974A1, 49)
    Formula:C25H28ClF2N5O2
    Color and Shape:Solid
    Molecular weight:503.97
  • Sovesudil hydrochloride


    Sovesudil (PHP-201) HCl: potent local ROCK inhibitor; targets ROCK I/II (IC50: 3.7/2.3 nM); lowers IOP, non-congesting.
    Formula:C23H23ClFN3O3
    Color and Shape:Solid
    Molecular weight:443.9
  • Zeltociclib

    CAS:
    <p>Zeltociclib is an inhibitor of cyclin-dependent kinases (CDKs) with anti-tumor properties.</p>
    Formula:C18H20F3N4O2P
    Color and Shape:Solid
    Molecular weight:412.346
  • Anticancer agent 29


    <p>Compound E/Z-6f, anticancer, IC50: CDK2 (0.054 μM), CDK1 (0.127 μM), CDK4 (0.129 μM), CDK6 (0.396 μM).</p>
    Formula:C22H15ClFNO
    Color and Shape:Solid
    Molecular weight:363.81
  • LNA-AMP

    CAS:
    LNA-AMP is a nucleotide analog used in the synthesis of oligonucleotides.
    Formula:C11H14N5O7P
    Color and Shape:Solid
    Molecular weight:359.23
  • CDK2 degrader 4

    CAS:
    <p>CDK2 degrader4 (compound 104) is a potent degrader of CDK2, showing promise for cancer research applications.</p>
    Formula:C23H26ClN3O5
    Color and Shape:Solid
    Molecular weight:459.923
  • WRN inhibitor 13

    CAS:
    WRN inhibitor 13 is an inhibitor of the WRN helicase with a pIC50 value ranging from 6 to 7.
    Formula:C16H20N2O5S
    Color and Shape:Solid
    Molecular weight:352.405
  • Dyrk1A/B-IN-1


    Dyrk1A/B-IN-1 (3n) is a potent DYRK1A/B inhibitor, cell-permeable, with Ki values of 67.8 nM (1A) and 237.9 nM (1B), IC50s of 1.1 and 0.8 μM.
    Formula:C21H17N3O2S2
    Color and Shape:Solid
    Molecular weight:407.51
  • PLK1-IN-5

    CAS:
    PLK1-IN-5, a potent PLK1 inhibitor, has an IC50 of less than 500 nM and demonstrates anticancer effects (WO2008113711A1; compound I-4) [1].
    Formula:C28H39N7O3
    Color and Shape:Solid
    Molecular weight:521.65
  • GR 122222X

    CAS:
    GR 122222X is an inhibitor of topoisomerase II.
    Formula:C26H35N5O11S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:625.65
  • Z4P

    CAS:
    Z4P, an IRE1 inhibitor with blood-brain barrier permeability (BBB), inhibited glioblastoma growth and recurrence in combination with Temozolomide.
    Formula:C19H24N2O2
    Purity:98.99%
    Color and Shape:Solid
    Molecular weight:312.41
  • CDK2-IN-31

    CAS:
    CDK2-IN-31 (compound I-125A) is an inhibitor of CDK2 and is utilized in cancer research.
    Formula:C37H52N6O5
    Color and Shape:Solid
    Molecular weight:660.85
  • BRD-7880

    CAS:
    BRD-7880 is a potent and highly specific inhibitor of aurora kinases B and C.
    Formula:C32H38N4O7
    Color and Shape:Solid
    Molecular weight:590.67
  • Antibacterial agent 110


    Compound 4e, an antibacterial against P. aeruginosa, disrupts cell membranes (MIC: 1 μg/ml).
    Formula:C22H21N5O4S
    Color and Shape:Solid
    Molecular weight:451.5
  • Dyrk1A-IN-8

    CAS:
    Dyrk1A-IN-8 is an active molecule that can be used in life science related research. The CAS number of Dyrk1A-IN-8 is 101578-13-6.
    Formula:C17H21N3O
    Color and Shape:Solid
    Molecular weight:283.37
  • Cdc7-IN-11

    CAS:
    Cdc7-IN-11 is a potent inhibitor of Cdc7 (IC50 ≤ 1 nM) and can be used in the study of proliferative diseases.
    Formula:C20H22F2N4O2S
    Color and Shape:Solid
    Molecular weight:420.48
  • MtTMPK-IN-7


    MtTMPK-IN-7 inhibits MtbTMPK (IC50: 47 μM), active against M. brevis (MIC: 2.3-4.7 μM), useful for tuberculosis research.
    Formula:C27H29ClN6O3
    Color and Shape:Solid
    Molecular weight:521.01
  • DYRK1-IN-1

    CAS:
    DYRK1-IN-1: Selective DYRK1A inhibitor with IC50 of 220 nM, good permeability, CNS penetrant for research, no P-glycoprotein issues.
    Formula:C12H12N6
    Color and Shape:Solid
    Molecular weight:240.26
  • Elacytarabine

    CAS:
    Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors.
    Formula:C27H45N3O6
    Purity:97.69%
    Color and Shape:Solid
    Molecular weight:507.66