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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3739 products of "Cell Cycle/Checkpoint"

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  • Ac-MRGDH-NH2


    <p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>
    Formula:C25H41N11O8S
    Color and Shape:Solid
    Molecular weight:655.727
  • Pyrindamycin A

    CAS:
    Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.
    Formula:C26H26ClN3O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:543.95
  • Anti-EMMPRIN/CD147 Antibody


    Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.
    Color and Shape:Odour Liquid
  • Barasertib

    CAS:
    AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.
    Formula:C26H31FN7O6P
    Purity:99.92% - 99.97%
    Color and Shape:Solid
    Molecular weight:587.54
  • 5'(R)-C-Methyl-5-fluorouridine


    5’(R)-C-Methyl-5-fluorouridine, a uridine analogue, possesses potential antiepileptic properties.
    Formula:C10H13FN2O6
    Color and Shape:Solid
    Molecular weight:276.22
  • (S)-DI-87

    CAS:
    <p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor,reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>
    Formula:C23H30N6O3S2
    Purity:99.42%
    Color and Shape:Soild
    Molecular weight:502.65
  • Lorutengitide

    CAS:
    <p>Lorutengitide is a transcription-regulating peptide with antiproliferative activity.</p>
    Formula:C30H50N8O12
    Color and Shape:Solid
    Molecular weight:714.764
  • dUTP trisodium

    CAS:
    <p>dUTP trisodium (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR.</p>
    Formula:C9H12N2Na3O14P3
    Purity:100.00%
    Color and Shape:Solid
    Molecular weight:534.09
  • 5'-O-DMT-Bz-rC

    CAS:
    <p>5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Formula:C37H35N3O8
    Color and Shape:Solid
    Molecular weight:649.69
  • Cytarabine triphosphate

    CAS:
    Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.
    Formula:C9H16N3O14P3
    Color and Shape:Solid
    Molecular weight:483.16
  • Aclacinomycin A

    CAS:
    Aclacinomycin A has a wide range of applications in life science related research.
    Formula:C42H53NO15
    Purity:99.43%
    Color and Shape:Solid
    Molecular weight:811.87
  • BLINK15


    BLINK15 is a blood-brain barrier-permeable Cdk5 inhibitor. It reduces CDK5 activity in CDK5/p35 (IC50= 29.34 nM) and CDK5/p25 (IC50= 12.08 nM) complexes. Additionally, BLINK15 exhibits antidiabetic and neuroprotective effects. It lowers blood glucose levels in type 2 diabetes (T2D) mice, enhances cognitive abilities, and diminishes neurodegenerative lesions.
    Color and Shape:Odour Solid
  • 5'-O-TBDMS-Bz-dA

    CAS:
    5’-O-TBDMS-Bz-dA is a nucleoside with protective and modification effects.
    Formula:C23H31N5O4Si
    Color and Shape:Solid
    Molecular weight:469.617
  • THK01

    CAS:
    <p>THK01: ROCK2 inhibitor (IC50=5.7nM), less effective on ROCK1 (923nM). Hinders breast cancer spread via ROCK2-STAT3. For cancer research.</p>
    Formula:C20H13N3O2
    Color and Shape:Solid
    Molecular weight:327.34
  • 5'-ODMT cEt G Phosphoramidite (Amidite)

    CAS:
    5'-ODMT cEt G Amidite is a safe, effective nucleic acid analog with strong antisense activity.
    Formula:C46H56N7O9P
    Color and Shape:Solid
    Molecular weight:881.95
  • Emicoron

    CAS:
    Importazole is an inhibitor of the transport receptor importin-β. It specifically inhibits importin-β likely by altering its interaction with RanGTP.
    Formula:C52H58N6O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:831.05
  • Thailanstatin C

    CAS:
    Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.
    Formula:C30H46ClNO9
    Color and Shape:Solid
    Molecular weight:600.15
  • DSPE-PEG5000-cRGD


    DSPE-PEG5000-cRGD is a PEG compound composed of DSPE and an αvβ3 targeting peptide (cRGD). The cRGD peptide has the ability to specifically bind to the αvβ3 present on the surfaces of numerous cancer cells and new vascular cells. DSPE-PEG5000-cRGD is useful for drug delivery applications.
    Color and Shape:Odour Solid
  • N1-Benzoyl pseudouridine


    N1-Benzoyl pseudouridine, a purine nucleoside analog, inhibits DNA synthesis and induces apoptosis to combat lymphoid cancers.
    Formula:C16H16N2O7
    Color and Shape:Solid
    Molecular weight:348.31
  • R-1479

    CAS:
    R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 μM for HCV RNA replication in the HCV subgenomic replicon system.
    Formula:C9H12N6O5
    Purity:98.11% - 99.95%
    Color and Shape:Solid
    Molecular weight:284.23