Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(111 products)
- CDK(526 products)
- Cell Cycle Arrest(4 products)
- Chk(46 products)
- DYRK(49 products)
- Dynamin(26 products)
- Ferroptosis(225 products)
- HSP(179 products)
- Integrin(256 products)
- Kinesin(87 products)
- LIM Kinase(19 products)
- Microtubule Associated(283 products)
- PKC(111 products)
- PLK(25 products)
- ROCK(66 products)
- Rho(2 products)
- Wee1(14 products)
- c-Myc(76 products)
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Found 3756 products of "Cell Cycle/Checkpoint"
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CDK12-IN-6
CAS:CDK12-IN-6, a pyrazolotriazine, strongly inhibits CDK12 (IC50 1.19 μM at 2 mM ATP), but not CDK2/Cyclin E or CDK9/Cyclin T1 (both IC50 >20 μM).Formula:C20H21F2N9Color and Shape:SolidMolecular weight:425.448LY2812223
CAS:LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).Formula:C10H12N4O4SPurity:98%Color and Shape:SolidMolecular weight:284.29CCT241533 dihydrochloride
CAS:Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.Formula:C23H29Cl2FN4O4Color and Shape:SolidMolecular weight:515.41Isocytosine
CAS:Compound PDK0016, with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0016 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C4H5N3OColor and Shape:White To Off-White SolidMolecular weight:111.1Antibacterial agent 144
Antibacterial Agent 144 (compound 8e) exhibits superior efficacy against multi-resistant Staphylococcus aureus compared to Chloromycin and Amoxicillin.Formula:C26H23N7O3Color and Shape:SolidMolecular weight:481.51Flurocitabine HCl
CAS:Fluorocitabine HCl, a cytarabine analog, hydrolyzes into ara-FC and ara-FU, showing antitumor effects in leukemia and solid cancers.Formula:C9H11ClFN3O4Purity:99.23% - 99.76%Color and Shape:SoildMolecular weight:279.655'-ODMT cEt G Phosphoramidite (Amidite)
CAS:5'-ODMT cEt G Amidite is a safe, effective nucleic acid analog with strong antisense activity.Formula:C46H56N7O9PColor and Shape:SolidMolecular weight:881.95CDK7-IN-5
CAS:CDK7-IN-5, a CDK7 inhibitor with an IC 50 value of less than 100 nM, exhibits potent anticancer properties (WO2015154022A1, Compound 104).Formula:C34H45N9O2Color and Shape:SolidMolecular weight:611.795PROTAC CDK9 degrader-2
CAS:PROTAC CDK9 degrader-2, potent, selective, IC50 17 μM in MCF-7, wogonin-derived, targets CRBN.Formula:C39H36N6O10Purity:98%Color and Shape:SolidMolecular weight:748.74DSPE-PEG2000-cRGD
DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.Color and Shape:Odour SolidNUAK1-IN-1
NUAK1-IN-1 (Compound 9) is an inhibitor of NUAK1 with an IC50 of 5.012 nM, as well as a CDK4 inhibitor. It is suitable for research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.Formula:C25H30N6OColor and Shape:SolidMolecular weight:430.545CDK12/13-IN-2
CDK12/13-IN-2 (Compound 24) is a covalent inhibitor of CDK12 and CDK13, exhibiting IC50 values of 15.5 nM and 12.2 nM, respectively. It effectively inhibits the proliferation of breast cancer cells and can be utilized in the research of triple-negative breast cancer.Formula:C24H22FN7O2Color and Shape:SolidMolecular weight:459.48CD532 hydrochloride
CD532 hydrochloride, potent Aurora A inhibitor (IC50=45 nM), hampers MYCN protein, changes AURKA's shape, aids cancer research.Color and Shape:SolidLDV FITC
CAS:fluorescent ligand that binds to the α4β1 integrin (VLA-4)Formula:C69H81N11O17SPurity:98%Color and Shape:SolidMolecular weight:1368.53Anti-MRSA agent 7
Compound 12: a potent anti-MRSA, inhibits S. aureus/E. coli DNA gyrases/topo IV; IC50: 0.185-0.365/0.341-0.059 μM.Formula:C22H20BrF2N3O4Color and Shape:SolidMolecular weight:508.31N3,5-Dimethyl-2'-O-(2-methoxyethyl) uridine
<p>N3,5-Dimethyl-2’-O-(2-methoxyethyl) uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>Formula:C14H22N2O7Color and Shape:SolidMolecular weight:330.33Anti-EMMPRIN/CD147 Antibody
Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.Color and Shape:Odour LiquiddAURK-4
CAS:dAURK-4, a derivative of Alisertib, functions as a potent and selective degrader of AURKA (Aurora A), exhibiting anticancer properties [1].Formula:C52H52ClFN8O12Color and Shape:SolidMolecular weight:1035.4711H-Benzo[a]carbazole
CAS:11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.Formula:C16H11NPurity:99.14%Color and Shape:SolidMolecular weight:217.27Guanosine triphosphate
CAS:Guanosine triphosphate (GTP), a native nucleotide, and its derivatives may serve as specific inhibitors against COVID-19 [1].Formula:C10H16N5O14P3Color and Shape:SolidMolecular weight:523.18
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