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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

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Found 3756 products of "Cell Cycle/Checkpoint"

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  • 5'-O-DMT-2'-O-TBDMS-Ac-rC

    CAS:
    5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.
    Formula:C38H47N3O8Si
    Color and Shape:Solid
    Molecular weight:701.892
  • DNA Gyrase-IN-6


    Agent 138: soluble benzothiazole, inhibits DNA gyrase/topoisomerase IV, targets Gram+ & Gram- bacteria, binds plasma proteins.
    Formula:C18H16Cl2N4O4S
    Color and Shape:Solid
    Molecular weight:455.32
  • PD-1/PD-L1-IN-50


    Compound LG-12, known chemically as PD-1/PD-L1-IN-50, is an inhibitor of PD-1/PD-L1. It enhances the secretion of IFN-γ, promotes the activation of CD8+ T cells, and activates T cell-mediated anti-tumor immunity.
    Color and Shape:Odour Solid
  • XT17


    XT17 is an anthrone compound with broad-spectrum antibacterial activity, exerting its effects by disrupting the cell wall and inhibiting DNA synthesis. It demonstrates weak hemolytic activity, low cytotoxicity to mammalian cell lines, and a low rate of resistance development. Additionally, XT17 shows in vivo efficacy in a mouse corneal infection model induced by Staphylococcus aureus or Pseudomonas aeruginosa. Further docking studies confirm that XT17 forms a stable complex with bacterial gyrase. XT17 is suitable for research in the field of anti-infective agents.
    Color and Shape:Odour Solid
  • Nogalamycin

    CAS:
    Nogalamycin is an anthracycline antibiotic with antitumor properties produced by soil bacteria Streptomyces nogalater.
    Formula:C39H49NO16
    Purity:98%
    Color and Shape:Solid
    Molecular weight:787.812
  • 4-Amino-1-(β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxamide


    4-Amino-1-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide is a purine nucleoside analog with broad antitumor activity against indolent lymphoid
    Formula:C12H15N5O5
    Color and Shape:Solid
    Molecular weight:309.28
  • Bz-rC Phosphoramidite

    CAS:
    <p>Bz-rC Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>
    Formula:C52H66N5O9PSi
    Color and Shape:Solid
    Molecular weight:964.185
  • Pseudorabies virus-IN-1


    <p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>
    Formula:C27H23ClF2N4O2
    Color and Shape:Solid
    Molecular weight:508.947
  • ONX 0801 trisodium

    CAS:
    ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor.
    Formula:C32H30N5Na3O10
    Color and Shape:Solid
    Molecular weight:713.58
  • c-Myc inhibitor 7

    CAS:
    c-Myc inhibitor 7 degrades c-MYC, CK1α, GSPT1, IKZF1/2/3 proteins in tumors, for research on related diseases.
    Formula:C35H30N6O5
    Color and Shape:Soild
    Molecular weight:614.65
  • 5'-O-TBDMS-N2-ibu-dG

    CAS:
    <p>5'-O-TBDMS-N2-ibu-dG: a nucleoside derivative with strong anti-BVDV activity, useful in lead compound synthesis.</p>
    Formula:C20H33N5O5Si
    Color and Shape:Solid
    Molecular weight:451.59
  • 1-(b-D-Xylofuranosyl)-N6-(p-methoxybenzyl) adenine


    1-(β-D-Xylofuranosyl)adenine is a purine analog with antitumor activity, inhibiting DNA synthesis and inducing apoptosis.
    Formula:C18H21N5O5
    Color and Shape:Solid
    Molecular weight:387.39
  • JB-11 isethionate

    CAS:
    JB-11 isethionate is a bioactive chemical.
    Formula:C21H29N5O7S
    Color and Shape:Solid
    Molecular weight:495.55
  • 3'-β-C-ethynyl-N6-(m-trifluoromethyl benzyl)adenosine


    3’-Beta-C-ethynyl-N6-(m-trifluoromethyl benzyl)adenosine is an adenosine analog.
    Formula:C20H18F3N5O4
    Color and Shape:Solid
    Molecular weight:449.38
  • R-BC154 acetate


    R-BC154 acetate: selective α9β1 antagonist, high-affinity integrin probe for α9β1/α4β1 activity study.
    Formula:C56H65N9O14S3
    Color and Shape:Solid
    Molecular weight:1184.36
  • L-5-Methyluridine

    CAS:
    L-5-Methyluridine, an L-configuration of 5-Methyluridine, is an endogenous methylated nucleoside present in human fluids.
    Formula:C10H14N2O6
    Color and Shape:Solid
    Molecular weight:258.23
  • DHFR-IN-9


    DHFR-IN-9 (compound 8A), a dihydrofolate reductase (DHFR) inhibitor, impedes purine and thymidylate biosynthesis, pivotal in cell proliferation and growth.
    Formula:C19H16N6S
    Color and Shape:Solid
    Molecular weight:360.44
  • EFdA-TP tetraammonium


    EFdA-TP tetraammonium is a potent HIV-1 RT inhibitor and DNA synthesis blocker, acting as an ICT or DCT.
    Formula:C12H27N9O12P3
    Color and Shape:Solid
    Molecular weight:601.31
  • Gly-Arg-Gly-Asp-Ser

    CAS:
    Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.
    Formula:C17H30N8O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:490.47
  • N1-(2-Methyl)propyl pseudouridine


    N1-(2-Methyl)propyl pseudouridine, a purine analog, targets lymphoid cancer by inhibiting DNA synthesis and inducing apoptosis.
    Formula:C13H20N2O6
    Color and Shape:Solid
    Molecular weight:300.31