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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3764 products of "Cell Cycle/Checkpoint"

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  • DSPE-PEG5000-cRGD


    DSPE-PEG5000-cRGD is a PEG compound composed of DSPE and an αvβ3 targeting peptide (cRGD). The cRGD peptide has the ability to specifically bind to the αvβ3 present on the surfaces of numerous cancer cells and new vascular cells. DSPE-PEG5000-cRGD is useful for drug delivery applications.
    Color and Shape:Odour Solid
  • JWZ-5-13


    JWZ-5-13 is an effective CDK7 PROTAC degrader that significantly degrades CDK7 via the ubiquitin-proteasome system. JWZ-5-13 also exhibits antitumor activity.
    Formula:C54H66N10O6S
    Molecular weight:982.48875
  • K34c hydrochloride

    CAS:
    <p>K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.</p>
    Formula:C26H30ClN3O4
    Purity:99.76% - 99.89%
    Color and Shape:Soild
    Molecular weight:483.99
  • GSK-1070916

    CAS:
    GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM.
    Formula:C30H33N7O
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:507.63
  • BSJ-03-204

    CAS:
    BSJ-03-204 is a selective Cdk4/6 degrader.
    Formula:C43H48N10O8
    Color and Shape:Solid
    Molecular weight:832.9
  • 8-iso Prostaglandin F1β

    CAS:
    8-iso Prostaglandin F1β,inducet vasoconstrictor effects in (PA), (PV) and (MA) through the activation of TXA2R, tyrosine kinase and Rho kinase.
    Formula:C20H36O5
    Color and Shape:Solid
    Molecular weight:356.5
  • CPS2

    CAS:
    CPS2: potent, selective PROTAC CDK2 degrader. IC50=24nM, targets acute myeloid leukemia research.
    Formula:C38H42N12O10S2
    Color and Shape:Solid
    Molecular weight:890.94
  • DSPE-PEG2000-cRGD


    DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.
    Color and Shape:Odour Solid
  • Barasertib

    CAS:
    AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.
    Formula:C26H31FN7O6P
    Purity:99.92% - 99.97%
    Color and Shape:Solid
    Molecular weight:587.54
  • Mps1-IN-6


    Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1].
    Formula:C35H39N9O3
    Color and Shape:Solid
    Molecular weight:633.74
  • Nusinersen

    CAS:
    Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.
    Purity:98.62%
    Color and Shape:Solid
  • 5'(R)-C-Methyl-5-fluorouridine


    5’(R)-C-Methyl-5-fluorouridine, a uridine analogue, possesses potential antiepileptic properties.
    Formula:C10H13FN2O6
    Color and Shape:Solid
    Molecular weight:276.22
  • (S)-DI-87

    CAS:
    <p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor,reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>
    Formula:C23H30N6O3S2
    Purity:99.42%
    Color and Shape:Soild
    Molecular weight:502.65
  • IV-361

    CAS:
    IV-361, an orally active and selective CDK7 inhibitor with a Ki value of less than or equal to 50 nM, demonstrates potent anti-cancer activity (US20190256531A1
    Formula:C23H32FN5O2Si
    Color and Shape:Solid
    Molecular weight:457.625
  • 3'-Deoxyuridine-5'-triphosphate trisodium


    3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).
    Formula:C9H12N2Na3O14P3
    Color and Shape:Soild
    Molecular weight:534.08
  • Aclacinomycin A

    CAS:
    Aclacinomycin A has a wide range of applications in life science related research.
    Formula:C42H53NO15
    Purity:99.43%
    Color and Shape:Solid
    Molecular weight:811.87
  • 5-Methylcytidine 5′-triphosphate

    CAS:
    5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innate
    Formula:C10H18N3O14P3
    Color and Shape:Solid
    Molecular weight:497.18
  • Xanthosine-5'-Triphosphate

    CAS:
    <p>Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.</p>
    Formula:C10H15N4O15P3
    Color and Shape:Solid
    Molecular weight:524.164
  • 5'-O-DMT-PAC-dA

    CAS:
    <p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>
    Formula:C39H37N5O7
    Color and Shape:Solid
    Molecular weight:687.74
  • 6-Thioguanosine

    CAS:
    6-Thioguanosine (6-Mercaptoguanosine) is an active nucleoside and low molecular weight gel.6-Thioguanosine has immunosuppressive properties.
    Formula:C10H13N5O4S
    Purity:97.05%
    Color and Shape:Yellow-Green Powder
    Molecular weight:299.31