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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3764 products of "Cell Cycle/Checkpoint"

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  • Cytarabine triphosphate

    CAS:
    Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.
    Formula:C9H16N3O14P3
    Color and Shape:Solid
    Molecular weight:483.16
  • PKMYT1-IN-6


    PKMYT1-IN-6 (compound 98) is an inhibitor of PKMYT1, exhibiting an IC50 of less than 50nM.
    Color and Shape:Odour Solid
  • 3'-Deoxyuridine-5'-triphosphate trisodium


    3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).
    Formula:C9H12N2Na3O14P3
    Color and Shape:Soild
    Molecular weight:534.08
  • DHFR-IN-21


    DHFR-IN-21 (compound 5p) is an inhibitor of dihydrofolate reductase.
    Color and Shape:Odour Solid
  • Netropsin

    CAS:
    Netropsin: polypeptide from Streptomyces, with antibiotic/antiviral properties, binds to A-T DNA regions, effective on Gram-positive/negative bacteria.
    Formula:C18H26N10O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:430.46
  • 3'-β-C-Methyl-2-thiouridine


    3’-β-C-Methyl-2-thiouridine, a purine nucleoside analog, exhibits extensive antitumor activity, particularly against indolent lymphoid malignancies.
    Formula:C10H14N2O5S
    Color and Shape:Solid
    Molecular weight:274.29
  • CDK12-IN-6

    CAS:
    CDK12-IN-6, a pyrazolotriazine, strongly inhibits CDK12 (IC50 1.19 μM at 2 mM ATP), but not CDK2/Cyclin E or CDK9/Cyclin T1 (both IC50 >20 μM).
    Formula:C20H21F2N9
    Color and Shape:Solid
    Molecular weight:425.448
  • 5'-O-DMT-PAC-dA

    CAS:
    <p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>
    Formula:C39H37N5O7
    Color and Shape:Solid
    Molecular weight:687.74
  • 6-Thioguanosine

    CAS:
    6-Thioguanosine (6-Mercaptoguanosine) is an active nucleoside and low molecular weight gel.6-Thioguanosine has immunosuppressive properties.
    Formula:C10H13N5O4S
    Purity:97.05%
    Color and Shape:Yellow-Green Powder
    Molecular weight:299.31
  • Uridine triphosphate 13C9,15N2 sodium

    CAS:
    Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.
    Formula:C9H1415N2NaO15P3
    Color and Shape:Solid
    Molecular weight:517.04
  • ROCK-IN-32

    CAS:
    ROCK-IN-32 is an effective Rho-kinase inhibitor.
    Formula:C20H17Cl2N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:402.27
  • Etrolizumab

    CAS:
    MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.
    Purity:98.9% (SDS-PAGE); 96.6% (SEC-HPLC) - 98.9% (SDS-PAGE); 96.6% (SEC-HPLC)
    Color and Shape:Liquid
  • 7-Deazaxanthine

    CAS:
    7-Deazaxanthine (7DX) is an inhibitor of thymidine phosphorylase (TPase) and reduces TPase activity in a concentration-dependent manner, with an IC50 value of 40 μM. Additionally, 7-Deazaxanthine exhibits significant anti-angiogenic properties.
    Formula:C6H5N3O2
    Color and Shape:Solid
    Molecular weight:151.12
  • Thailanstatin C

    CAS:
    Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.
    Formula:C30H46ClNO9
    Color and Shape:Solid
    Molecular weight:600.15
  • 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

    CAS:
    dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.
    Formula:C10H14N5Na2O8P
    Color and Shape:Solid
    Molecular weight:409.202
  • DSPE-PEG1000-cRGD


    DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.
    Color and Shape:Odour Solid
  • CDK9-IN-25


    <p>CDK9-IN-25 (compound 4a), an imidazopyrazine derivative, functions as a CDK9 inhibitor with an IC50 of 0.24 μM.</p>
    Formula:C15H16FN5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:285.32
  • Erythromycin glutamate

    CAS:
    Erythromycin glutamate is a macrolide bacteriostatic antibiotic. This antibiotic is metabolized through the liver and inhibits cytochrome enzyme P450A 3A41.
    Formula:C42H76N2O17
    Purity:98%
    Color and Shape:Solid
    Molecular weight:881.067
  • Chk1-IN-6

    CAS:
    <p>Chk1-IN-6 is a potent, selective, and orally bioavailable CHK1 inhibitor candidate.</p>
    Formula:C16H18F3N7
    Color and Shape:Solid
    Molecular weight:365.364
  • CBR-2092

    CAS:
    CBR-2092 is a DNA-directed RNA polymerase and DNA topoisomerase inhibitor.
    Formula:C65H81FN6O15
    Color and Shape:Solid
    Molecular weight:1205.388